Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Terence D Sanger"'
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250001 (2021)
The design of myocontrolled devices faces particular challenges in children with dyskinetic cerebral palsy because the electromyographic signal for control contains both voluntary and involuntary components. We hypothesized that voluntary and involun
Externí odkaz:
https://doaj.org/article/a64e85b265a842f08d3f2a39e71d088c
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125461 (2015)
The role of motor uncertainty in discrete or static space tasks, such as pointing tasks, has been investigated in many experiments. These studies have shown that humans hold an internal representation of intrinsic and extrinsic motor uncertainty and
Externí odkaz:
https://doaj.org/article/28769ae374744c50bc43df0175a6981d
Publikováno v:
Frontiers in Human Neuroscience, Vol 8 (2015)
For children with severe cerebral palsy (CP), social and emotional interactions can be significantly limited due to impaired speech motor function. However, if it is possible to extract continuous voluntary control signals from the electromyograph (E
Externí odkaz:
https://doaj.org/article/86f0254ce39545edbe9aa16ea959fec8
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139988 (2015)
Fitts' Law describes the speed-accuracy trade-off of human movements, and it is an elegant strategy that compensates for random and uncontrollable noise in the motor system. The control strategy during targeted movements may also take into account th
Externí odkaz:
https://doaj.org/article/8d0ed3da2e0743e3a08594679eb64922
Publikováno v:
Frontiers in Computational Neuroscience, Vol 8 (2014)
The lack of multi-scale empirical measurements (e.g. recording simultaneously from neurons, muscles, whole body, etc.) complicates understanding of sensorimotor function in humans. This is particularly true for the understanding of development during
Externí odkaz:
https://doaj.org/article/e6d68efd3e3a4838806ad8dcf5255613
Autor:
Jaya Nataraj, Jennifer A. MacLean, Jordan Davies, Joshua Kurtz, Amanda Salisbury, Mark A. Liker, Terence D. Sanger, Joffre Olaya
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
IntroductionMitochondrial Enoyl CoA Reductase Protein-Associated Neurodegeneration (MEPAN) syndrome is a rare inherited metabolic condition caused by MECR gene mutations. This gene encodes a protein essential for fatty acid synthesis, and defects cau
Externí odkaz:
https://doaj.org/article/e05f0f45e2144e75be61ecadb6e7c08a
Autor:
Jennifer A. MacLean, Jaya Nataraj, Jordan Davies, Aleksandra Zakharova, Joshua Kurtz, Mark A. Liker, Joffre Olaya, Terence D. Sanger
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2023)
IntroductionDeep brain stimulation (DBS) is a well-documented therapy for dystonia utilized in many adult and pediatric movement disorders. Pedunculopontine nucleus (PPN) has been investigated as a DBS target primarily in adult patients with dystonia
Externí odkaz:
https://doaj.org/article/9da1ee1babf54ab2ab0cd2f6aca45b80
Autor:
Jennifer A. MacLean, Terence D. Sanger
Publikováno v:
Brain Stimulation, Vol 16, Iss 2, Pp 558-560 (2023)
Externí odkaz:
https://doaj.org/article/9c0259b73a704082822e021ae6110372
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionBenzodiazepines (BDZs) are commonly used to treat the symptoms of movement disorders; however, deep brain stimulation (DBS) has become a popular treatment for these disorders. Previous studies have investigated the effects of BDZ on corti
Externí odkaz:
https://doaj.org/article/c80debd605984096a2c3a10019d499c1
Autor:
Estefania Hernandez-Martin, Maral Kasiri, Sumiko Abe, Jennifer MacLean, Joffre Olaya, Mark Liker, Jason Chu, Terence D. Sanger
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107066- (2023)
Summary: The rate model of basal ganglia function predicts that muscle activity in dystonia is due to disinhibition of thalamus resulting from decreased inhibitory input from pallidum. We seek to test this hypothesis in children with dyskinetic cereb
Externí odkaz:
https://doaj.org/article/de1163fe29074120b325fcfff17ac327