Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Terence C.W. Poon"'
Autor:
Pengwei Zhang, Irene L. Ang, Melody M.T. Lam, Rui Wei, Kate M.K. Lei, Xingwang Zhou, Henry H.N. Lam, Qing‐Yu He, Terence C.W. Poon
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/50d3ab4987e6494d80614720654767fc
Autor:
Yue-Sun Cheung, Henry L.Y. Chan, John Wong, Kit-Fai Lee, Terence C.W. Poon, Nathalie Wong, Paul B.S. Lai
Publikováno v:
Asian Journal of Surgery, Vol 31, Iss 2, Pp 41-49 (2008)
We aimed to evaluate the role of elevated perioperative alanine aminotransferase (ALT) as a surrogate marker of hepatitis activity in determining the risk of recurrence and survival in hepatitis B-related hepatocellular carcinoma (HCC) after curative
Externí odkaz:
https://doaj.org/article/0b8d3b1ba3284cbeb6a75a396ec6651b
Autor:
Wei Zhou, Kin Yip Tam, Shan Yu, Qingyu Zhang, Alice S.T. Wong, Terence C.W. Poon, Yufei Jiao, Leo T. O. Lee, Yaojun Ju, Sally K. Y. To
Publikováno v:
Oncogene. 40:97-111
As a result of the hostile microenvironment, metabolic alterations are required to enable the malignant growth of cancer cells. To understand metabolic reprogramming during metastasis, we conducted shotgun proteomic analysis of highly metastatic (HM)
Autor:
Irene L. Ang, Simon Ming-Yuen Lee, Qiwen Liao, Terence C.W. Poon, Gandhi Rádis-Baptista, Guiyi Gong, Shirley W. I. Siu, Kate M. K. Lei, Clarence T. T. Wong
Publikováno v:
Archives of Toxicology. 93:1745-1767
Venoms from marine animals have been recognized as a new emerging source of peptide-based therapeutics. Several peptide toxins from sea anemone have been investigated as therapeutic leads or pharmacological tools. Venom complexity should be further h
Autor:
Shuo Yang, Lipeng Zhu, Jie Liu, Guangyu Zhou, Xuanjun Zhang, Yubin Liu, Qi Zhao, Zhen Yuan, Kai Miao, Guofang Ma, Chu-Xia Deng, Terence C.W. Poon, Irene L. Ang, Fengjuan Zhang, Hoi Man Ng
Publikováno v:
Chemical communications (Cambridge, England). 55(95)
In this study, we constructed bioconjugates of targeting immune checkpoint B7-H3 antibody and chlorin e6 to treat non-small cell lung cancer under the guidance of spectroscopic photoacoustic and fluorescence imaging. The B7-H3-Ce6 conjugates could di
Autor:
Xiaowen Guan, Terence C.W. Poon, Jianming Zeng, Bing Zhu, Hailin Wang, Xianju Wang, Ruiyu Xie, Un Lam Choi, Xuanjun Zhang, Jun Xiong, Gang Li, Qiang Dong, Hongjie Zhang, Melody M. T. Lam, Ting Zhang
Publikováno v:
Epigenetics & Chromatin
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-17 (2019)
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-17 (2019)
Background TET-mediated oxidation of 5-mC participates in both passive and active DNA demethylation, which exerts a significant influence on diverse biological processes. Mass spectrometry has identified multiple phosphorylation sites of TET2. Howeve
Autor:
Melody M. T. Lam, Kate M. K. Lei, Wan Chan, Pengwei Zhang, Rui Wei, Irene L. Ang, Terence C.W. Poon
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Fragmentation reactions of protonated α-amino acids (AAs) were studied previously using tandem mass spectrometry (MS/MS) of unit mass resolution. Isobaric fragmentation products and minor fragmentation products could have been overlooked or misannot
Autor:
Rui Wei, Wan Chan, Pengwei Zhang, Terence C.W. Poon, Melody M. T. Lam, Irene L. Ang, Kate M. K. Lei
Publikováno v:
Molecules
Volume 24
Issue 4
Molecules, Vol 24, Iss 4, p 747 (2019)
Volume 24
Issue 4
Molecules, Vol 24, Iss 4, p 747 (2019)
Cystine is an important biomolecule in living systems. Although collision-induced dissociation (CID)-based tandem mass spectrometry (MS/MS) is commonly applied for identification and quantification of cystine in both biomedical and nutritional studie
Autor:
Alice S.T. Wong, Melody M. T. Lam, Shan Yu, Terence C.W. Poon, Qingyu Zhang, Yufei Jiao, Litao Sun, Leo T. O. Lee
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-18 (2019)
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-18 (2019)
Background Angiotensin II (ANGII) and its receptor (AGTR1) have been proposed as significant contributors to metastasis in multiple cancers. Further, high AGTR1 levels are associated with poor epithelial ovarian cancer (EOC) outcomes. However, the me
Autor:
Zhizhen Chen, Jie Liu, Dezhi Li, Wu Su, Gui-yang Yao, Qi Zhao, Zhongyu Zhu, Bing-Nan Han, Dimiter S. Dimitrov, Terence C.W. Poon, Rui Wei
Publikováno v:
mAbs. 10(5)
Site-specific conjugation of small molecules to antibody molecules is a promising strategy for generation of antibody-drug conjugates. In this report, we describe the successful synthesis of a novel bifunctional molecule, 6-(azidomethyl)-2-pyridineca