Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Terence C. Owen"'
Publikováno v:
Journal of Chromatographic Science; July 1970, Vol. 8 Issue: 7 pD24-D24, 1p
Autor:
Robert D. Kendig, David J. Merkler, Robert Malka, Geoffrey H. Chew, Kathleen A. Merkler, Benjamin J. Wilcox, Jodi Dusi, Casey C. Cosner, Neil R. McIntyre, Edward W. Lowe, Paul C. Kline, Lamar Galloway, Mindy Romero, Natalie Carballo, Laura E. Baumgart, Lawrence King, Sarah E. Carpenter, Alexander S. Asser, Terence C. Owen, Andrew B. Lowe
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:10061-10074
Peptidyl alpha-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of alpha-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human dis
Autor:
Terence C. Owen
Publikováno v:
Bioorganic Chemistry. 36:156-160
Thiols, simple and complex, including polypeptide and protein thiols, react rapidly and selectively with esters of propiolic acid under very mild conditions (aqueous buffer, room temperature, pH 7) to give thioacrylates. These stable derivatives exhi
Publikováno v:
Berg, K, Andersen, H & Owen, T C 2004, ' The regulation of rhinovirus infection in vitro by IL-8, HuIFN-alpha, and TNF-alpha ', APMIS Supplementum, vol. 112, no. 3, pp. 172-82 . https://doi.org/10.1111/j.1600-0463.2004.apm1120303.x
The influence of three important cytokines (IL-8, TNF-alpha, and HuIFN-alpha) on ongoing rhinovirus infections has been examined in vitro, individually or as combinations. TNF-alpha was able to transform traces of HRV infections into full-blown infec
Publikováno v:
Journal of Immunological Methods. 157:233-240
A new tetrazolium compound, MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3- carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt), has recently been described which in the presence of phenazine methosulfate (PMS) is reduced by living cells to y
Publikováno v:
Natural Toxins. 1:303-307
The cytotoxicity of Fusarium mycotoxins was evaluated using a trichothecene sensitive cell line (BHK-21, baby hamster kidney cells) in combination with the MTT-cleavase test as an end-point measurement. Cells tended to be more sensitive to the type A
Autor:
Joseph K. Leone, Terence C. Owen
Publikováno v:
ChemInform. 24
Autor:
Terence C. Owen
Publikováno v:
Journal of Heterocyclic Chemistry. 27:987-990
Acidity constants (pKa) of the hydroxyl groups of the quaternary heterocyclonium carbinols 2-hydroxymethyl-1-methylpyridinium and 2-(1-hydroxyethyl)-1,3-dimethylbenzimidazolium ions are 11.5 ± 0.5. Acidity constants of the corresponding gem diols, t
Autor:
David J. Merkler, Terence C. Owen
Publikováno v:
Medical hypotheses. 62(3)
The title enzyme, peptidylglycine alpha-hydroxylating monooxygenase (PHM), is essential to the in vivo generation of a wide variety of physiologically significant alpha-amidated peptide hormones from the corresponding C-terminal glycine-extended proh
Autor:
Terence C. Owen, David J. Austin
Publikováno v:
The Journal of Organic Chemistry. 58:756-758