Zobrazeno 1 - 10
of 804
pro vyhledávání: '"Ter protein"'
Autor:
Vincenzo Costanzo, Karina Zadorozhny, Luca Pellegrini, Lumir Krejci, Arun Mouli Kolinjivadi, Anna De Antoni, Alberto Ciccia, Vincenzo Sannino, Mairi L. Kilkenny, Hervé Técher, Rong Shen, G. Baldi
Publikováno v:
Molecular Cell
Summary Brca2 deficiency causes Mre11-dependent degradation of nascent DNA at stalled forks, leading to cell lethality. To understand the molecular mechanisms underlying this process, we isolated Xenopus laevis Brca2. We demonstrated that Brca2 prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b845cdc9cb12d2c6f65a7763d12a360
Publikováno v:
Current Genetics. 63:607-611
Chromosome replication in Eubacteria is initiated by initiator protein(s) binding to specific sites within the replication origin, oriC. Recently, initiator protein binding to chromosomal regions outside the origin has attracted renewed attention; as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a4da6618fefd52cc376c023b94501c
https://doi.org/10.1007/s00294-016-0671-6
https://doi.org/10.1007/s00294-016-0671-6
Publikováno v:
Current Biology. 26:3257-3268
ETAA1 (Ewing tumor-associated antigen 1), also known as ETAA16, was identified as a tumor-specific antigen in the Ewing family of tumors. However, the biological function of this protein remains unknown. Here, we report the identification of ETAA1 as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eea1b5015d19e96c83a862ad90f37cf
https://doi.org/10.1016/j.cub.2016.10.030
https://doi.org/10.1016/j.cub.2016.10.030
Autor:
Peter H. von Hippel, Brett Israels, Davis Jose, John P. Gillies, Wonbae Lee, Andrew H. Marcus
Publikováno v:
Nucleic Acids Research
Gene 32 protein (gp32) is the single-stranded (ss) DNA binding protein of the bacteriophage T4. It binds transiently and cooperatively to ssDNA sequences exposed during the DNA replication process and regulates the interactions of the other sub-assem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5e8e4ba912efd949552c52bad7e79d
https://doi.org/10.1093/nar/gkw863
https://doi.org/10.1093/nar/gkw863
Publikováno v:
Genomics Data, Vol 7, Iss, Pp 162-165 (2016)
Genomics Data
Genomics Data
The genome of the budding yeast Saccharomyces cerevisiae is sequenced and the location and dynamic of activation of DNA replication origins are known. G1 synchronized yeast cells can be released into S-phase in the presence of hydroxyurea (HU) (1), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4368172a90bc2a7909e51bb0564625
Publikováno v:
Biochemical and Biophysical Research Communications. 470:546-551
Arrest of replication fork progression is one of the most common causes for increasing the genomic instability. In bacteria, PriA, a conserved DEXH-type helicase, plays a major role in recognition of the stalled forks and restart of DNA replication.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f9ff54d7b22af76b03d91e0dcd13f5
https://doi.org/10.1016/j.bbrc.2016.01.108
https://doi.org/10.1016/j.bbrc.2016.01.108
Publikováno v:
Virology. 489:212-222
The vaccinia virus I3L gene encodes a single-stranded DNA binding protein (SSB) that is essential for virus DNA replication and is conserved in all Chordopoxviruses. The I3 protein contains a negatively charged C-terminal tail that is a common featur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fba3ed7cff57ac9fab518d794f51ea2
Autor:
Karla A. Mettrick, Ian Grainge
Publikováno v:
Nucleic Acids Research
Replication of chromosomal DNA must be carried out to completion in order for a cell to proliferate. However, replication forks can stall during this process for a variety of reasons, including nucleoprotein 'roadblocks' and DNA lesions. In these cir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dcd6b6c1f41b16aa8c9b0e4ada03625
http://europepmc.org/articles/PMC4737137
http://europepmc.org/articles/PMC4737137
Autor:
Ildiko Hajdu, Nicholas A. Willis, Alexander P. Boardman, Richard O. Adeyemi, Andrew E. H. Elia, Elizabeth Lowry, Steven P. Gygi, Stephen J. Elledge, Ralph Scully, David C. Wang
Publikováno v:
Molecular Cell. 60:280-293
We have used quantitative proteomics to profile ubiquitination in the DNA damage response (DDR). We demonstrate that RPA, which functions as a protein scaffold in the replication stress response, is multiply ubiquitinated upon replication fork stalli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f1a817d06797a9d2cde847e4d2d9ec
https://doi.org/10.1016/j.molcel.2015.09.011
https://doi.org/10.1016/j.molcel.2015.09.011
Autor:
Ken-ichi Mizuno, Andrea Keszthelyi, Yasukazu Daigaku, Izumi Miyabe, Saed Mohebi, Johanne M. Murray, Meliti Skouteri, Antony M. Carr, Thomas A. Kunkel
Publikováno v:
Nature structural & molecular biology
To maintain genetic stability DNA must be replicated only once and replication completed even when individual replication forks are inactivated. Because fork inactivation is common, the passive convergence of an adjacent fork is insufficient to rescu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4196a98fbf6a108bf1d340f7b8b7748c
http://europepmc.org/articles/PMC4655445
http://europepmc.org/articles/PMC4655445