Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination (U-Act-Early): a multicentre, randomised, double-blind, double-dummy, strategy trial

Autor: Bijlsma, Johannes W J, Welsing, Paco M J, Woodworth, Thasia G, Middelink, Leonie M, Pethö-Schramm, Attila, Bernasconi, Corrado, Borm, Michelle E A, Wortel, Cornelis H, ter Borg, Evert Jan, Jahangier, Z Nazira, van der Laan, Willemijn H, Bruyn, George A W, Baudoin, Paul, Wijngaarden, Siska, Vos, Petra A J M, Bos, Reinhard, Starmans, Mirian J F, Griep, Eduard N, Griep-Wentink, Joanna R M, Allaart, Cornelia F, Heurkens, Anton H M, Teitsma, Xavier M, Tekstra, Janneke, Marijnissen, Anne Carien A, Lafeber, Floris P J, Jacobs, Johannes W G

Publikováno v: In The Lancet 23-29 July 2016 388(10042):343-355

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Necessity of TNF-alpha inhibitor discontinuation in rheumatoid arthritis is predicted by smoking and number of previously used biological DMARDs

Autor: Cuppen, Bart V.J., Jacobs, Johannes W.G., ter Borg, Evert Jan, Marijnissen, Anne C.A., Bijlsma, Johannes W.J., Lafeber, Floris P.J.G., van Laar, Jacob M.

Publikováno v: Cuppen, B V J, Jacobs, J W G, ter Borg, E J, Marijnissen, A C A, Bijlsma, J W J, Lafeber, F P J G, van Laar, J M & on behalf of all SRU investigators 2017, ' Necessity of TNF-alpha inhibitor discontinuation in rheumatoid arthritis is predicted by smoking and number of previously used biological DMARDs ', Clinical and Experimental Rheumatology, vol. 35, no. 2, pp. 221-228 .
Clinical and Experimental Rheumatology, 35(2), 221-228. Clinical and Experimental Rheumatology S.A.S.
Clinical and Experimental Rheumatology, 35(2), 221. Clinical and Experimental Rheumatology S.A.S.

Objective Despite the success of TNF-alpha inhibitor (TNFi) treatment in rheumatoid arthritis (RA), a substantial number of patients necessitate discontinuation. Prediction thereof would be clinically relevant and guide the decision whether to start

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aa28dd18ce8668f9418e43cb9e4027d5
https://research.vumc.nl/en/publications/efac7f16-ada1-438d-a6a4-df8bc1057080

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