Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Teppei Fujikawa"'
Autor:
Takuya Yoshida, Mina Fujitani, Scotlynn Farmer, Ami Harada, Zhen Shi, Jenny J. Lee, Arely Tinajero, Ashish K. Singha, Teppei Fujikawa
Publikováno v:
Molecular Metabolism, Vol 77, Iss , Pp 101792- (2023)
Objective: To adapt to metabolically challenging environments, the central nervous system (CNS) orchestrates metabolism of peripheral organs including skeletal muscle. The organ-communication between the CNS and skeletal muscle has been investigated,
Externí odkaz:
https://doaj.org/article/172aaafc424a45f8acff900cdcf87233
Publikováno v:
Molecular Metabolism, Vol 73, Iss , Pp 101745- (2023)
Background: Neuroplasticity refers to the brain's ability to undergo functional and structural changes in response to diverse challenges. Converging evidence supports the notion that exercise serves as a metabolic challenge, triggering the release of
Externí odkaz:
https://doaj.org/article/c6fff76d01654589955d0d3e9da3735f
Autor:
Teppei Fujikawa, Yun-Hee Choi, Dong Joo Yang, Dong Min Shin, Jose Donato, Daisuke Kohno, Charlotte E. Lee, Carol F. Elias, Syann Lee, Ki Woo Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 4, Pp 1-9 (2019)
Metabolism: Enzymatic subunit essential to brain’s glucose responses A particular subunit of a critical signaling enzyme is needed for neurons inside the brain’s hypothalamus to properly regulate energy metabolism. Ki Woo Kim from Yonsei Universi
Externí odkaz:
https://doaj.org/article/140c2a65c43e419cb301c26994d328f7
Autor:
Ashish Singha, Juan Pablo Palavicini, Meixia Pan, Scotlynn Farmer, Darleen Sandoval, Xianlin Han, Teppei Fujikawa
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Leptin is a potent endocrine hormone produced by adipose tissue and regulates a broad range of whole-body metabolism such as glucose and lipid metabolism, even without insulin. Central leptin signaling can lower hyperglycemia in insulin-deficient rod
Externí odkaz:
https://doaj.org/article/cfc92c31dbac45a0bbdd6e77bf8cd508
Autor:
Jason G. Anderson, Giorgio Ramadori, Rafael M. Ioris, Mirco Galiè, Eric D. Berglund, Katie C. Coate, Teppei Fujikawa, Stefania Pucciarelli, Benedetta Moreschini, Augusto Amici, Cristina Andreani, Roberto Coppari
Publikováno v:
Molecular Metabolism, Vol 4, Iss 11, Pp 846-856 (2015)
Objective: Available treatment for obesity and type 2 diabetes mellitus (T2DM) is suboptimal. Thus, identifying novel molecular target(s) exerting protective effects against these metabolic imbalances is of enormous medical significance. Sirt6 loss-
Externí odkaz:
https://doaj.org/article/342ca602a10d4d6e8cd7632471dd0105
Autor:
Alexandre Caron, Heather M Dungan Lemko, Carlos M Castorena, Teppei Fujikawa, Syann Lee, Caleb C Lord, Newaz Ahmed, Charlotte E Lee, William L Holland, Chen Liu, Joel K Elmquist
Publikováno v:
eLife, Vol 7 (2018)
Leptin is critical for energy balance, glucose homeostasis, and for metabolic and neuroendocrine adaptations to starvation. A prevalent model predicts that leptin’s actions are mediated through pro-opiomelanocortin (POMC) neurons that express lepti
Externí odkaz:
https://doaj.org/article/24478469d7784efb8a6ac25e389c9bb8
Autor:
Teppei Fujikawa, Carlos M Castorena, Mackenzie Pearson, Christine M Kusminski, Newaz Ahmed, Pavan K Battiprolu, Ki Woo Kim, Syann Lee, Joseph A Hill, Philipp E Scherer, William L Holland, Joel K Elmquist
Publikováno v:
eLife, Vol 5 (2016)
Exercise has numerous beneficial metabolic effects. The central nervous system (CNS) is critical for regulating energy balance and coordinating whole body metabolism. However, a role for the CNS in the regulation of metabolism in the context of the e
Externí odkaz:
https://doaj.org/article/6d58bf1dd8944b4c95eeb7c5c29d4ec8
Autor:
Joel K. Elmquist, Amanda G. Arnold, Madison Granier, Charlotte E. Lee, Jiwon Lee, Teppei Fujikawa, Carlos M. Castorena, Natalie J. Michael, Arely Salazar Tinajero, Alexandre Caron, William L. Holland, Syann Lee, Chelsea Limboy, Newaz Ahmed, Chen Liu, Jay D. Horton, Simeng Wang
Publikováno v:
Am J Physiol Endocrinol Metab
Cannabinoid 1 receptor (CB1R) inverse agonists reduce body weight and improve several parameters of glucose homeostasis. However, these drugs have also been associated with deleterious side effects. CB1R expression is widespread in the brain and in p
Autor:
Sakie Katsumura, Nadeem Siddiqui, Michael Rock Goldsmith, Jaime H. Cheah, Teppei Fujikawa, Genki Minegishi, Atsushi Yamagata, Yukako Yabuki, Kaoru Kobayashi, Mikako Shirouzu, Takeshi Inagaki, Tim H.-M. Huang, Nicolas Musi, Ivan Topisirovic, Ola Larsson, Masahiro Morita
Publikováno v:
Cell Metab
Hepatokines, secretory proteins from the liver, mediate inter-organ communication to maintain a metabolic balance between food intake and energy expenditure. However, molecular mechanisms by which hepatokine levels are rapidly adjusted following stim
Autor:
Takuya Yoshida, Scotlynn Farmer, Ami Harada, Zhen Shi, Jenny J. Lee, Arely Tinajero, Ashish K. Singha, Teppei Fujikawa
To adapt to metabolically challenging environments, the central nervous system (CNS) orchestrates metabolism of peripheral organs including skeletal muscle. The organ-communication between the CNS and skeletal muscle has been investigated, yet our un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f47b8a3d898c892a7893cb1e8fc141c
https://doi.org/10.1101/2022.04.01.486756
https://doi.org/10.1101/2022.04.01.486756