Harnessing biomaterial architecture to drive anticancer innate immunity.

Autor: Davis MA; Department of Biomedical Engineering, Boston University, Boston, Massachusetts, 02215, USA. mtep@bu.edu., Cho E; Department of Biomedical Engineering, Boston University, Boston, Massachusetts, 02215, USA. mtep@bu.edu., Teplensky MH; Department of Biomedical Engineering, Boston University, Boston, Massachusetts, 02215, USA. mtep@bu.edu.; Department of Materials Science and Engineering, Boston University, Boston, Massachusetts, 02215, USA.

Publikováno v: Journal of materials chemistry. B [J Mater Chem B] 2023 Nov 29; Vol. 11 (46), pp. 10982-11005. Date of Electronic Publication: 2023 Nov 29.

Multi-antigen spherical nucleic acid cancer vaccines.

Autor: Teplensky MH; Department of Chemistry and International Institute for Nanotechnology, Northwestern University, Evanston, IL, USA., Evangelopoulos M; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA., Dittmar JW; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA., Forsyth CM; Department of Chemistry and International Institute for Nanotechnology, Northwestern University, Evanston, IL, USA.; Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, USA., Sinegra AJ; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA., Wang S; Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, USA., Mirkin CA; Department of Chemistry and International Institute for Nanotechnology, Northwestern University, Evanston, IL, USA. chadnano@northwestern.edu.; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA. chadnano@northwestern.edu.; Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, USA. chadnano@northwestern.edu.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2023 Jul; Vol. 7 (7), pp. 911-927. Date of Electronic Publication: 2023 Jan 30.

Modular Nucleic Acid Scaffolds for Synthesizing Monodisperse and Sequence-Encoded Antibody Oligomers.

Autor: Winegar PH; Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.; International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.; These authors contributed equally., Figg CA; Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.; International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.; These authors contributed equally., Teplensky MH; Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.; International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA., Ramani N; International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.; Department of Materials Science and Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA., Mirkin CA; Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.; International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.; Department of Materials Science and Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.; Lead contact.

Publikováno v: Chem [Chem] 2022 Nov 10; Vol. 8 (11), pp. 3018-3030. Date of Electronic Publication: 2022 Aug 05.

Spherical nucleic acids as an infectious disease vaccine platform.

Autor: Teplensky MH; Department of Chemistry, Northwestern University, Evanston, IL 60208.; International Institute for Nanotechnology, Northwestern University, Evanston, IL 60208., Distler ME; Department of Chemistry, Northwestern University, Evanston, IL 60208.; International Institute for Nanotechnology, Northwestern University, Evanston, IL 60208., Kusmierz CD; Department of Chemistry, Northwestern University, Evanston, IL 60208.; International Institute for Nanotechnology, Northwestern University, Evanston, IL 60208., Evangelopoulos M; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208., Gula H; Howard T. Ricketts Laboratory, Department of Microbiology, University of Chicago, Chicago, IL 60637., Elli D; Howard T. Ricketts Laboratory, Department of Microbiology, University of Chicago, Chicago, IL 60637., Tomatsidou A; Howard T. Ricketts Laboratory, Department of Microbiology, University of Chicago, Chicago, IL 60637., Nicolaescu V; Howard T. Ricketts Laboratory, Department of Microbiology, University of Chicago, Chicago, IL 60637., Gelarden I; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611., Yeldandi A; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611., Batlle D; Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611., Missiakas D; Howard T. Ricketts Laboratory, Department of Microbiology, University of Chicago, Chicago, IL 60637., Mirkin CA; Department of Chemistry, Northwestern University, Evanston, IL 60208.; International Institute for Nanotechnology, Northwestern University, Evanston, IL 60208.; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Apr 05; Vol. 119 (14), pp. e2119093119. Date of Electronic Publication: 2022 Mar 21.

Spherical Nucleic Acid Vaccine Structure Markedly Influences Adaptive Immune Responses of Clinically Utilized Prostate Cancer Targets.

Autor: Teplensky MH; Department of Chemistry and the International Institute for Nanotechnology, Northwestern University, Evanston, IL, 60208, USA., Dittmar JW; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA., Qin L; Department of Medicine, Division of Hematology and Oncology, Northwestern University, Chicago, IL, 60611, USA., Wang S; Interdisciplinary Biological Sciences Program, Northwestern University, Evanston, IL, 60208, USA., Evangelopoulos M; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA., Zhang B; Department of Medicine, Division of Hematology and Oncology, Northwestern University, Chicago, IL, 60611, USA., Mirkin CA; Department of Chemistry and the International Institute for Nanotechnology, Northwestern University, Evanston, IL, 60208, USA.; Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2021 Nov; Vol. 10 (22), pp. e2101262. Date of Electronic Publication: 2021 Sep 08.