Výsledky vyhledávání - "Teodoro Zornoza"

N-Acetylcysteine normalizes brain oxidative stress and neuroinflammation observed after protracted ethanol abstinence: a preclinical study in long-term ethanol-experienced male rats

Autor: Sandra Fernández-Rodríguez, María José Cano-Cebrián, Claudia Esposito-Zapero, Salvador Pérez, Consuelo Guerri, Teodoro Zornoza, Ana Polache

Publikováno v: Psychopharmacology. 240:725-738

Rationale Using a preclinical model based on the Alcohol Deprivation Effect (ADE), we have reported that N-Acetylcysteine (NAC) can prevent the relapse-like drinking behaviour in long-term ethanol-experienced male rats. Objectives To investigate if c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41fd0cffcb214c5610a216e1e4191b90
https://doi.org/10.1007/s00213-023-06311-z

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Akademický článek

The Effects of N-Acetylcysteine on the Rat Mesocorticolimbic Pathway: Role of mGluR5 Receptors and Interaction with Ethanol

Autor: Sandra Fernández-Rodríguez, Claudia Esposito-Zapero, Teodoro Zornoza, Ana Polache, Luis Granero, María José Cano-Cebrián

Publikováno v: Pharmaceuticals, Vol 14, Iss 6, p 593 (2021)

N-acetylcysteine (NAC) is a prodrug that is marketed as a mucolytic agent and used for the treatment of acetaminophen overdose. Over the last few decades, evidence has been gathered that suggests the potential use of NAC as a new pharmacotherapy for

Externí odkaz: https://doaj.org/article/41ac3723eaa5499a94eee1ab27b46167

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The Effects of N-Acetylcysteine on the Rat Mesocorticolimbic Pathway: Role of mGluR5 Receptors and Interaction with Ethanol

Autor: Ana Polache, Luis Granero, Teodoro Zornoza, Claudia Esposito-Zapero, Sandra Fernández-Rodríguez, M. J. Cano-Cebrián

Publikováno v: Pharmaceuticals
Fernández Rodríguez, Sandra Esposito-Zapero, Claudia Zornoza Sabina, Teodoro Polache Vengut, Ana Granero Maciá, Luis Cano Cebrián, María José 2021 The Effects of N-Acetylcysteine on the Rat Mesocorticolimbic Pathway: Role of mGluR5 Receptors and Interaction with Ethanol Pharmaceuticals 14(6) 593 1 12
Pharmaceuticals, Vol 14, Iss 593, p 593 (2021)
RODERIC. Repositorio Institucional de la Universitat de Valéncia
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a81d5b835c052eb1e0e62e1a5a3c3f6
http://europepmc.org/articles/PMC8233914

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Efficacy of N-acetylcysteine in the prevention of alcohol relapse-like drinking: Study in long-term ethanol-experienced male rats

Autor: Luis Granero, Lucía Hipólito, M. J. Cano-Cebrián, Ana Polache, Sandra Fernández-Rodríguez, Teodoro Zornoza

Publikováno v: Cano-Cebrián MJ, Fernández-Rodríguez S, Hipólito L, Granero L, Polache A, Zornoza T. Efficacy of N-acetylcysteine in the prevention of alcohol relapse-like drinking: Study in long-term ethanol-experienced male rats. J Neurosci Res. 2021 Feb;99(2):638-648.
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname

Alcohol use disorders are chronic and highly relapsing disorders, thus alcoholic patients have a high rate of recidivism for drug use even after long periods of abstinence. The literature points to the potential usefulness of N-acetylcysteine (NAC) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec3c3c81079acdbba70fda610cbfe89
https://hdl.handle.net/10550/81571

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Regional differences in mu-opioid receptor-dependent modulation of basal dopamine transmission in rat striatum

Autor: Yolanda Campos-Jurado, M. J. Cano-Cebrián, Lucía Martí-Prats, Luis Granero, Teodoro Zornoza, Ana Polache

Publikováno v: Neuroscience Letters. 638:102-108

The nigrostriatal dopamine system is implicated in the regulation of reward and motor activity. Dopamine (DA) release in dorsal striatum (DS) is controlled by the firing rate of DA neurons in substantia nigra pars compacta. However, influences at ter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e3f2308595e1d73852018d3e95bda6
https://doi.org/10.1016/j.neulet.2016.12.024

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Activation of MORs in the VTA induces changes on cFos expression in different projecting regions: Effect of inflammatory pain

Autor: Luis Granero, Teodoro Zornoza, Ana Polache, Lucía Hipólito, Carmen Agustín-Pavón, Yolanda Campos-Jurado, Marta Igual-Lopez, Félix Padilla

Publikováno v: Neurochemistry international. 131

Chronic pain is a worldwide major health problem and many pain-suffering patients are under opioid based therapy. Epidemiological data show that pain intensity correlates with the risk of misuse of prescription opioids, and other drugs of abuse inclu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f508b435c1a879e0d85d0b1d0a7c2a
https://pubmed.ncbi.nlm.nih.gov/31419453

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Antidepressant efficacy of a selective organic cation transporter blocker in a mouse model of depression

Autor: Teodoro Zornoza, Franck Louis, Sara Rezai Amin, Rodolphe Alves de Sousa, Patrick M. Dansette, Carole Gruszczynski, Sophie Gautron, Vincent Vialou, Alejandro Orrico-Sanchez, Basile Coutens, Nicolas Pietrancosta, Francine Acher, Bruno P. Guiard, Laetitia Chausset-Boissarie, Assia Hessani, Bruno Giros

Publikováno v: Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2019, ⟨10.1038/s41380-019-0548-4⟩
Molecular Psychiatry, 2020, 25 (6), pp.1245-1259. ⟨10.1038/s41380-019-0548-4⟩

International audience; Current antidepressants act principally by blocking monoamine reuptake by high-affinity transporters in the brain. However, these antidepressants show important shortcomings such as slow action onset and limited efficacy in ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359a2c1742a246517d0a349fbbcb63e7
https://hal.archives-ouvertes.fr/hal-02351247

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Acetaldehyde sequestration by d-penicillamine prevents ethanol relapse-like drinking in rats: evidence from an operant self-administration paradigm

Autor: Lucía Martí-Prats, Ana Polache, Luis Granero, Teodoro Zornoza, José Antonio López-Moreno

Publikováno v: Psychopharmacology. 232:3597-3606

Previous experiments in our laboratory have shown that d-penicillamine (DP) (acetaldehyde sequestering agent) is able to block the increase in ethanol consumption observed after a period of imposed deprivation (the so-called alcohol deprivation effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd88665c7d7ceaf318955d0da071ae0
https://doi.org/10.1007/s00213-015-4011-1

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