Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Teodora Nikolova"'
Autor:
Max J. Carlsson, Anastasia S. Vollmer, Philipp Demuth, Daniel Heylmann, Diana Reich, Caroline Quarz, Birgit Rasenberger, Teodora Nikolova, Thomas G. Hofmann, Markus Christmann, Julia A. Fuhlbrueck, Simone Stegmüller, Elke Richling, Alexander T. Cartus, Jörg Fahrer
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-15 (2022)
Abstract Liver cancer is one of the most frequent tumor entities worldwide, which is causally linked to viral infection, fatty liver disease, life-style factors and food-borne carcinogens, particularly aflatoxins. Moreover, genotoxic plant toxins inc
Externí odkaz:
https://doaj.org/article/c606c1d1550a4850a16f00ca5d673cd2
Autor:
Henning Formes, Joana P. Bernardes, Amrit Mann, Franziska Bayer, Giulia Pontarollo, Klytaimnistra Kiouptsi, Katrin Schäfer, Sebastian Attig, Teodora Nikolova, Thomas G. Hofmann, Jörn M. Schattenberg, Hristo Todorov, Susanne Gerber, Philip Rosenstiel, Tobias Bopp, Felix Sommer, Christoph Reinhardt
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103092- (2021)
Summary: The gut microbiota affects remote organ functions but its impact on organotypic endothelial cell (EC) transcriptomes remains unexplored. The liver endothelium encounters microbiota-derived signals and metabolites via the portal circulation.
Externí odkaz:
https://doaj.org/article/ee0261277c8044a4afde1def618b2469
Autor:
Anja Göder, Claudia Emmerich, Teodora Nikolova, Nicole Kiweler, Maria Schreiber, Toni Kühl, Diana Imhof, Markus Christmann, Thorsten Heinzel, Günter Schneider, Oliver H. Krämer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Checkpoint kinases control cell cycle progression via the regulation of many key regulators. Here the authors demonstrate how HDAC1 and HDAC2 modulate checkpoint kinase signalling via the suppression of PR130, a regulatory subunit of the trimeric ser
Externí odkaz:
https://doaj.org/article/1ced4836ae484e558c659722b88a91e8
Autor:
Julian Fauß, Bettina Sprang, Petra Leukel, Clemens Sommer, Teodora Nikolova, Florian Ringel, Ella L. Kim
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 7 (2021)
Aldehyde dehydrogenase 1 isoforms A1 and A3 have been implicated as functional biomarkers associated with distinct molecular subtypes of glioblastoma and glioblastoma stem cells. However, the exact roles of these isoforms in different types of glioma
Externí odkaz:
https://doaj.org/article/91db099f54f04f62aa928d3de050d0a5
Autor:
Teodora Nikolova, Bernd Kaina, Kerstin Borgmann, Mengwan Wang, Nadine Piecha, Andrea Piée-Staffa, Nancy Berte
Structures of CCNU and HR inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd7ea25c69df8cabfa5b66788ba6249
https://doi.org/10.1158/1535-7163.22506594
https://doi.org/10.1158/1535-7163.22506594
PDF file - 78 KB, Apoptosis and necrosis rates of cell death data for glioblastoma and malignant melanoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfe7913f1c6675a7a1406700ce0c356
https://doi.org/10.1158/1535-7163.22499812
https://doi.org/10.1158/1535-7163.22499812
Autor:
Teodora Nikolova, Bernd Kaina, Kerstin Borgmann, Mengwan Wang, Nadine Piecha, Andrea Piée-Staffa, Nancy Berte
Malignant gliomas exhibit a high level of intrinsic and acquired drug resistance and have a dismal prognosis. First- and second-line therapeutics for glioblastomas are alkylating agents, including the chloroethylating nitrosoureas (CNU) lomustine, ni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fce105862f01cb99f2b33a6059b2ad7
https://doi.org/10.1158/1535-7163.c.6538440.v1
https://doi.org/10.1158/1535-7163.c.6538440.v1
PDF file - 53 KB, Doubling times for selected cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798c20d3728e6fc491a27e04abd3cca7
https://doi.org/10.1158/1535-7163.22499818.v1
https://doi.org/10.1158/1535-7163.22499818.v1
The major cytotoxic DNA adduct induced by temozolomide and other methylating agents used in malignant glioma and metastasized melanoma therapy is O6-methylguanine (O6-MeG). This primary DNA damage is converted by mismatch repair into secondary lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c48dc11dfe708612e31a50f496cacc38
https://doi.org/10.1158/1535-7163.c.6536269
https://doi.org/10.1158/1535-7163.c.6536269
PDF file - 78 KB, Apoptosis and necrosis rates of cell death data for fibroblasts and lymphoblastoid cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2e4929ae5bc398e7055530af034060
https://doi.org/10.1158/1535-7163.22499815
https://doi.org/10.1158/1535-7163.22499815