Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Teodor G, Păunescu"'
Autor:
Api Chewcharat, Elizabeth A. Phipps, Khushboo Bhatia, Sahir Kalim, Andrew S. Allegretti, Meghan E. Sise, Teodor G. Păunescu, Rituvanthikaa Seethapathy, Sagar U. Nigwekar
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Olfactory and gustatory changes may contribute to poor appetite and food aversion in chronic kidney disease (CKD), though the prevalence of olfactory and gustatory dysfunction is not known in the CKD population. Methods We conduct
Externí odkaz:
https://doaj.org/article/c73b930bc28b4bc79638299cef05f7d6
Autor:
Kenji Tsuji, Teodor G. Păunescu, Hani Suleiman, Dongping Xie, Fahmy A. Mamuya, Jeffrey H. Miner, Hua A. Jenny Lu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Helium ion scanning microscopy (HIM) is a novel technology that directly visualizes the cell surface ultrastructure without surface coating. Despite its very high resolution, it has not been applied extensively to study biological or patholo
Externí odkaz:
https://doaj.org/article/7e560862969a41ccb11700805fd53622
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131719 (2015)
In renal collecting duct (CD) principal cells (PCs), vasopressin (VP) acts through its receptor, V2R, to increase intracellular cAMP leading to phosphorylation and apical membrane accumulation of the water channel aquaporin 2 (AQP2). The trafficking
Externí odkaz:
https://doaj.org/article/762737926adc46528aa63a0ec67e9a6f
Autor:
William L Rice, Alfred N Van Hoek, Teodor G Păunescu, Chuong Huynh, Bernhard Goetze, Bipin Singh, Larry Scipioni, Lewis A Stern, Dennis Brown
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57051 (2013)
Helium ion scanning microscopy is a novel imaging technology with the potential to provide sub-nanometer resolution images of uncoated biological tissues. So far, however, it has been used mainly in materials science applications. Here, we took advan
Externí odkaz:
https://doaj.org/article/66da959dc9f44ca69e61c1d90bdc155e
Autor:
Teodor G Păunescu, Steven Rodriguez, Eric Benz, Mary McKee, Robert Tyszkowski, Mark W Albers, Dennis Brown
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45395 (2012)
The vacuolar proton-pumping ATPase (V-ATPase) is the main mediator of intracellular organelle acidification and also regulates transmembrane proton (H(+)) secretion, which is necessary for an array of physiological functions fulfilled by organs such
Externí odkaz:
https://doaj.org/article/b53394e4450f421786fc7c2e09d57506
Autor:
Ming Huang, Teodor G. Păunescu, Baoxue Yang, Kenji Tsuji, Dongping Xie, Hua A. Jenny Lu, Fahmy A. Mamuya, Onju Ham, Limin Su, Lei Lei
Publikováno v:
American Journal of Physiology-Renal Physiology. 314:F306-F316
Aquaporin-2 (AQP2) is a water channel protein expressed in principal cells (PCs) of the kidney collecting ducts (CDs) and plays a critical role in mediating water reabsorption and urine concentration. AQP2 undergoes both regulated trafficking mediate
Autor:
James M. Daley, Kenji Tsuji, Jeffrey H. Miner, Hua A. Jenny Lu, Teodor G. Păunescu, Hani Suleiman, Diane E. Capen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
The glomerulus exercises its filtration barrier function by establishing a complex filtration apparatus consisting of podocyte foot processes, glomerular basement membrane and endothelial cells. Disruption of any component of the glomerular filtratio
Autor:
Heyu Ji, Hua A. Jenny Lu, William Jin, Huihui Huang, Ming Huang, Junying Yuan, Teodor G. Păunescu, Diane E. Capen, Yin Xia
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Gentamicin is a potent aminoglycoside antibiotic that targets gram-negative bacteria, but nephrotoxicity limits its clinical application. The cause of gentamicin-induced AKI has been attributed mainly to apoptosis of the proximal tubule c
Autor:
Diane E. Capen, Dongping Xie, Shuai Zhu, Teodor G. Păunescu, Ming Huang, Kenji Tsuji, Onju Ham, Huihui Huang, Baoxue Yang, Jinzhao He, Hua A. Jenny Lu, William Jin, Weining Lu
Publikováno v:
J Am Soc Nephrol
Background Necroptosis is a newly discovered cell death pathway that plays a critical role in AKI. The involvement of integrin-linked kinase (ILK) in necroptosis has not been studied. Methods We performed experiments in mice with an Ilk deletion in c
Publikováno v:
The FASEB Journal. 32