Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers.

Autor: Pittet LF; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Messina NL; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Orsini F; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Moore CL; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Abruzzo V; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Barry S; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Bonnici R; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Bonten M; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Campbell J; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Croda J; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Dalcolmo M; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Gardiner K; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Gell G; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Germano S; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Gomes-Silva A; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Goodall C; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Gwee A; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Jamieson T; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Jardim B; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Kollmann TR; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Lacerda MVG; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Lee KJ; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Lucas M; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Lynn DJ; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Manning L; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Marshall HS; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., McDonald E; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Munns CF; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Nicholson S; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., O'Connell A; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., de Oliveira RD; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Perlen S; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Perrett KP; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Prat-Aymerich C; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Richmond PC; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Rodriguez-Baño J; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Dos Santos G; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., da Silva PV; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Teo JW; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Villanueva P; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Warris A; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Wood NJ; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Davidson A; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain., Curtis N; From the Infectious Diseases Group (L.F.P., N.L.M., V.A., R.B., K.G., G.G., S.G., C.G., A.G., T.J., E.M., S.P., J.W.T., P.V., N.C.), Melbourne Children's Trials Centre (F.O., C.L.M., K.J.L., K.P.P., A.D.), and the Clinical Epidemiology and Biostatistics Unit (F.O., C.L.M., K.J.L.), Murdoch Children's Research Institute, the Department of Paediatrics, University of Melbourne (L.F.P., N.L.M., A.G., K.J.L., K.P.P., P.V., N.C.), the Infectious Diseases Unit (L.F.P., A.G., P.V., N.C.), Research Operations (K.G.), and the Department of Allergy and Immunology (K.P.P.), Royal Children's Hospital Melbourne, and the Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity (S.N.), Parkville, VIC, Precision Medicine Theme, South Australian Health and Medical Research Institute (S.B., D.J.L.), the Department of Thoracic Medicine, Royal Adelaide Hospital (S.B.), and Adelaide Medical School and Robinson Research Institute, University of Adelaide (H.S.M.), Adelaide, SA, Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute (T.R.K., L.M., P.C.R.), the Department of Immunology, PathWest, Queen Elizabeth II Medical Centre (M.L.), the Department of Immunology, Sir Charles Gairdner Hospital (M.L.), and the Department of Immunology and General Paediatrics, Perth Children's Hospital (M.L., P.C.R.), Nedlands, WA, the University of Western Australia Medical School, Perth (M.L., L.M., P.C.R.), Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA (D.J.L.), the Department of Infectious Diseases, Fiona Stanley Hospital, Murdoch, WA (L.M.), the Vaccinology and Immunology Research Trials Unit, Women's and Children's Health Network, North Adelaide, SA (H.S.M.), the Department of Endocrinology and Diabetes, Children's Hospital at Westmead (C.F.M.), Sydney Children's Hospitals Network (N.J.W.), and the National Centre for Immunisation Research and Surveillance of Vaccine Preventable Disease (N.J.W.), Westmead, NSW, and the Faculty of Medicine and Health, University of Sydney, Sydney (C.F.M., N.J.W.) - all in Australia; the Infectious Diseases Unit, Department of Pediatrics, Gynecology, and Obstetrics, Faculty of Medicine, University of Geneva and University Hospitals of Geneva, Geneva (L.F.P.); the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (M.B., C.P.-A.); Exeter Collaboration for Academic Primary Care (J. Campbell) and Exeter Clinical Trials Unit (A.O.), University of Exeter Medical School, and the Medical Research Council Centre for Medical Mycology, University of Exeter (A.W.) - both in Exeter, United Kingdom; Fiocruz Mato Grosso do Sul, Fundação Oswaldo Cruz (J. Croda), and Universidade Federal de Mato Grosso do Sul (J. Croda, R.D.O., P.V.S.), Campo Grande, Helio Fraga Reference Center, Oswaldo Cruz Foundation Ministry of Health (M.D., G.S.), Catholic University (M.D.), and Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (A.G.-S.), Rio de Janeiro, and the Institute of Clinical Research Carlos Borborema, Doctor Heitor Vieira Dourado Tropical Medicine Foundation (B.J., M.V.G.L.), and Instituto Leônidas and Maria Deane, Oswaldo Cruz Foundation Ministry of Health (M.V.G.L.), Manaus - all in Brazil; the Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT (J. Croda); University of Texas Medical Branch, Galveston (M.V.G.L.); and Institut d'Investigació Germans Trias i Pujol, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Barcelona (C.P.-A.), the Division of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, and the Department of Medicine, University of Seville, Biomedicines Institute of Seville-Consejo Superior de Investigaciones Científicas, Seville (J.R.-B.), and CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid (J.R.-B.) - all in Spain.

Publikováno v: The New England journal of medicine [N Engl J Med] 2023 Apr 27; Vol. 388 (17), pp. 1582-1596.

Targeted Antibacterial Strategy Based on Reactive Oxygen Species Generated from Dioxygen Reduction Using an Organoruthenium Complex.

Autor: Weng C; Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore., Shen L; Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore., Teo JW; Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore., Lim ZC; Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore., Loh BS; Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore., Ang WH; Department of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore.; NUS Graduate School - Integrative Sciences and Engineering Programme, National University of Singapore, 21 Lower Kent Ridge Road, Singapore 119077, Singapore.

Publikováno v: JACS Au [JACS Au] 2021 Sep 07; Vol. 1 (9), pp. 1348-1354. Date of Electronic Publication: 2021 Sep 07 (Print Publication: 2021).

In Vitro Three-Dimensional Accuracy of Digital Implant Impressions: The Effect of Implant Angulation.

Autor: Chia VA, Esguerra RJ, Teoh KH, Teo JW, Wong KM, Tan KB

Publikováno v: The International journal of oral & maxillofacial implants [Int J Oral Maxillofac Implants] 2017 Mar/Apr; Vol. 32 (2), pp. 313–321. Date of Electronic Publication: 2017 Feb 23.

Development and evaluation of a multiplex real-time PCR for the detection of IMP, VIM, and OXA-23 carbapenemase gene families on the BD MAX open system.

Autor: Teo JW; National University Hospital, Department of Laboratory Medicine, Division of Microbiology, Singapore, 119074, Republic of Singapore. Electronic address: Jeanette_Teo@nuhs.edu.sg., La MV; National Public Health Laboratory, Ministry of Health, 3 Biopolis Drive, Synapse #05-14/16, Singapore, 138623, Republic of Singapore., Lin RT; National University Hospital, Department of Laboratory Medicine, Division of Microbiology, Singapore, 119074, Republic of Singapore; National Public Health Laboratory, Ministry of Health, 3 Biopolis Drive, Synapse #05-14/16, Singapore, 138623, Republic of Singapore.

Publikováno v: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2016 Dec; Vol. 86 (4), pp. 358-361. Date of Electronic Publication: 2016 Aug 26.

Emergence of a New Delhi metallo-β-lactamase-1-producing Pseudomonas aeruginosa in Singapore.

Autor: Teo JW; Department of Laboratory Medicine, Division of Microbiology, National University Hospital, Singapore 119074, Republic of Singapore., La MV; National Public Health Laboratory, Ministry of Health, Synapse, Singapore 138623, Republic of Singapore., Jureen R; Department of Laboratory Medicine, Division of Microbiology, National University Hospital, Singapore 119074, Republic of Singapore., Lin RT; Department of Laboratory Medicine, Division of Microbiology, National University Hospital, Singapore 119074, Republic of Singapore.; National Public Health Laboratory, Ministry of Health, Synapse, Singapore 138623, Republic of Singapore.

Publikováno v: Emerging microbes & infections [Emerg Microbes Infect] 2015 Nov 25; Vol. 4 (11), pp. e72. Date of Electronic Publication: 2015 Nov 25.