Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Tenzin Passang"'
Autor:
Sruthi Ravindranathan, Tenzin Passang, Jian-Ming Li, Shuhua Wang, Rohan Dhamsania, Michael Brandon Ware, Mohammad Y. Zaidi, Jingru Zhu, Maria Cardenas, Yuan Liu, Sanjeev Gumber, Brian Robinson, Anish Sen-Majumdar, Hanwen Zhang, Shanmuganathan Chandrakasan, Haydn Kissick, Alan B. Frey, Susan N. Thomas, Bassel F. El-Rayes, Gregory B. Lesinski, Edmund K. Waller
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Poor antitumor response of pancreatic cancer to immunotherapies is a major barrier to effective disease management. Herein we show that pancreatic cancers overexpress vasoactive intestinal peptide, and pharmacological inhibition of its signaling sign
Externí odkaz:
https://doaj.org/article/954e43b7b1f84c9eb8712e29586d1565
Autor:
Hanwen Zhang, Tenzin Passang, Sruthi Ravindranathan, Ramireddy Bommireddy, Mohammad Raheel Jajja, Lily Yang, Periasamy Selvaraj, Chrystal M. Paulos, Edmund K. Waller
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In the past decades, advances in the use of adoptive cellular therapy to treat cancer have led to unprecedented responses in patients with relapsed/refractory or late-stage malignancies. However, cellular exhaustion and senescence limit the efficacy
Externí odkaz:
https://doaj.org/article/2761c9d9689e4781abddac2165544691
Autor:
Yuan Liu, Susan Thomas, Mohammad Zaidi, Shuhua Wang, Haydn Kissick, Gregory Lesinski, Alan Frey, Sruthi Ravindranathan, Edmund Waller, Michael Ware, Bassel El-rayes, Rohan Dhamsania, Jingru Zhu, Anish Majumdar, Brian Robinson, Maria Cardenas, Tenzin Passang Fnu, Jian Ming Li, Sanjeev Gumber, Shanmuganathan Chandrakasan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/ef457d1db40045839ffa75158ef24e6a
Autor:
Heather Lin, Ruby Freeman, Alysa Evans, Tenzin Passang Fnu, Tongrui Liu, Elyse Christensen, Raymond Fei, Tanisha Sinha, Sruthi Ravindranathan, Lily Yang, Edmund Waller, Sarwish Rafiq
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Tenzin Passang, Sruthi Ravindranathan, Jian-Ming Li, Shuhua Wang, Michael Brandon Ware, Hanwen Zhang, Gregory B. Lesinski, Edmund K. Waller
Publikováno v:
Cancer Research. 82:C007-C007
Current immune checkpoint therapies including anti-CTLA-4 and anti-PD1 have limited efficacy in the treatment of pancreatic ductal adenocarcinoma (PDAC), largely due to a paucity of effector T cells within the tumor microenvironment (TME). In our stu
Autor:
Shuhua Wang, Tenzin Passang, Yiwen Li, Hanwen Zhang, Pankoj Kumar Das, Kevin Chen, Christopher R. Funk, Edmund K. Waller
Publikováno v:
Blood. 140:10219-10220
Autor:
Jian-Ming LI, Tenzin Passang, Pankoj Kumar Das, Shuhua Wang, Anish Sen-Majumdar, Nikolaos Papadantoonakis, Cynthia R. Giver, Edmund K. Waller
Publikováno v:
Blood. 140:4955-4956
Autor:
Edmund K. Waller, Maria Cardenas, Gregory B. Lesinski, Bassel F. El-Rayes, Jingru Zhu, Mohammad Y. Zaidi, Shuhua Wang, Brian S. Robinson, Michael B. Ware, Susan N. Thomas, Yuan Liu, Tenzin Passang Fnu, Shanmuganathan Chandrakasan, Sruthi Ravindranathan, Jian-Ming Li, Alan B. Frey, Rohan K. Dhamsania, Sanjeev Gumber, Anish Majumdar, Haydn T. Kissick
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundPaucity of T cells in the immune privileged tumor microenvironment (TME) of pancreatic ductal adenocarcinoma (PDAC) is a major reason that PDAC is refractory to immune checkpoint blockade.1 In this study, we show that human PDAC tumors over
Autor:
Sruthi Ravindranathan, Tenzin Passang, Jian-Ming Li, Shuhua Wang, Rohan Dhamsania, Michael Brandon Ware, Mohammad Y. Zaidi, Jingru Zhu, Maria Cardenas, Yuan Liu, Sanjeev Gumber, Brian Robinson, Anish Sen-Majumdar, Hanwen Zhang, Shanmuganathan Chandrakasan, Haydn Kissick, Alan B. Frey, Susan N. Thomas, Bassel F. El-Rayes, Gregory B. Lesinski, Edmund K. Waller
Publikováno v:
Nature communications. 13(1)
A paucity of effector T cells within tumors renders pancreatic ductal adenocarcinoma (PDAC) resistant to immune checkpoint therapies. While several under-development approaches target immune-suppressive cells in the tumor microenvironment, there is l
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