Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tenzin Kunchok"'
Autor:
Keene L Abbott, Ahmed Ali, Bradley I Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D Landis, Rachel A Hongo, Kirsten L Young, Tenzin Kunchok, Christopher S Nabel, Kayla D Crowder, Johnathan R Kent, Maria Lucia L Madariaga, Rakesh K Jain, Kathryn E Beckermann, Caroline A Lewis, Clary B Clish, Alexander Muir, W Kimryn Rathmell, Jeffrey Rathmell, Matthew G Vander Heiden
Publikováno v:
eLife, Vol 13 (2024)
The tumor microenvironment is a determinant of cancer progression and therapeutic efficacy, with nutrient availability playing an important role. Although it is established that the local abundance of specific nutrients defines the metabolic paramete
Externí odkaz:
https://doaj.org/article/3b4cd2338c48457fa0f024644fdf44e6
Publikováno v:
MicrobiologyOpen, Vol 12, Iss 5, Pp n/a-n/a (2023)
Abstract The oral cavity is colonized by a plethora of bacteria, fungi, and archaea, including streptococci of the mitis group (MSG) and the yeast Candida albicans. This study aims to investigate the role of streptococcal species in the development o
Externí odkaz:
https://doaj.org/article/07eeaa98b38a486aa8ec921c2eceb0b0
Autor:
Vaishnavi V. Phadnis, Jamie Snider, Venkateshwari Varadharajan, Iyappan Ramachandiran, Amy A. Deik, Zon Weng Lai, Tenzin Kunchok, Elinor Ng Eaton, Carolin Sebastiany, Anna Lyakisheva, Kyle D. Vaccaro, Juliet Allen, Zhong Yao, Victoria Wong, Betty Geng, Kipp Weiskopf, Clary B. Clish, J. Mark Brown, Igor Stagljar, Robert A. Weinberg, Whitney S. Henry
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113023- (2023)
Summary: Ferroptosis is a form of regulated cell death with roles in degenerative diseases and cancer. Excessive iron-catalyzed peroxidation of membrane phospholipids, especially those containing the polyunsaturated fatty acid arachidonic acid (AA),
Externí odkaz:
https://doaj.org/article/f1a03612f457448787c70b44eca61b6d
Autor:
Mark R Sullivan, Laura V Danai, Caroline A Lewis, Sze Ham Chan, Dan Y Gui, Tenzin Kunchok, Emily A Dennstedt, Matthew G Vander Heiden, Alexander Muir
Publikováno v:
eLife, Vol 8 (2019)
Cancer cell metabolism is heavily influenced by microenvironmental factors, including nutrient availability. Therefore, knowledge of microenvironmental nutrient levels is essential to understand tumor metabolism. To measure the extracellular nutrient
Externí odkaz:
https://doaj.org/article/9527455619a74344a76fc049642a495d
Akademický článek
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Autor:
Keene L. Abbott, Ahmed Ali, Dominick Casalena, Brian T. Do, Raphael Ferreira, Jaime H. Cheah, Christian K. Soule, Amy Deik, Tenzin Kunchok, Daniel R. Schmidt, Steffen Renner, Sophie E. Honeder, Michelle Wu, Sze Ham Chan, Tenzin Tseyang, Daniel Greaves, Peggy P. Hsu, Christopher W. Ng, Chelsea J. Zhang, Ali Farsidjani, Iva Monique T. Gramatikov, Nicholas J. Matheson, Caroline A. Lewis, Clary B. Clish, Matthew G. Rees, Jennifer A. Roth, Lesley Mathews Griner, Alexander Muir, Douglas S. Auld, Matthew G. Vander Heiden
SUMMARYA challenge for screening new candidate drugs to treat cancer is that efficacy in cell culture models is not always predictive of efficacy in patients. One limitation of standard cell culture is a reliance on non-physiological nutrient levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::121795f51a2d3bf410bf9d8120ac9c3b
https://doi.org/10.1101/2023.02.25.529972
https://doi.org/10.1101/2023.02.25.529972
Autor:
Dr. Prasurjya Bora, Dr. Tanu Nangia, Dr. Aditya Saxena, Dr. Tenzin Kunchok, Dr. Aayushi Sangal
Publikováno v:
International Journal of Applied Dental Sciences. 8:384-391
Autor:
Mangalhara, Kailash Chandra, Varanasi, Siva Karthik, Johnson, Melissa A., Burns, Mannix J., Rojas, Gladys R., Esparza Moltó, Pau B., Sainz, Alva G., Tadepalle, Nimesha, Abbott, Keene L., Mendiratta, Gaurav, Dan Chen, Farsakoglu, Yagmur, Tenzin Kunchok, Hoffmann, Filipe Araujo, Parisi, Bianca, Rincon, Mercedes, Vander Heiden, Matthew G., Bosenberg, Marcus, Hargreaves, Diana C., Kaech, Susan M.
Publikováno v:
Science; 9/22/2023, Vol. 381 Issue 6664, p1316-1323, 8p, 5 Diagrams
Autor:
Caroline A. Lewis, Tong Zhang, David M. Sabatini, Navdeep S. Chandel, Antonia Henne, Hans-Georg Sprenger, Andrew L. Cangelosi, Tenzin Kunchok, Jessica B. Spinelli, Julian M. Roessler, Kendall J. Condon, Jessica L. Mann, Anna M. Puszynska, Paul C. Rosen
Publikováno v:
Science. 374:1227-1237
For electrons to continuously enter and flow through the mitochondrial electron transport chain (ETC), they must ultimately land on a terminal electron acceptor (TEA), which is known to be oxygen in mammals. Paradoxically, we find that complex I and
Autor:
Vaishnavi V. Phadnis, Jamie Snider, Victoria Wong, Kyle D. Vaccaro, Tenzin Kunchok, Juliet Allen, Zhong Yao, Betty Geng, Kipp Weiskopf, Igor Stagljar, Whitney S. Henry, Robert A. Weinberg
SummaryFerroptosis is a form of regulated cell death with roles in degenerative diseases and cancer. Ferroptosis is driven by excessive iron-dependent peroxidation of membrane phospholipids, especially those containing the polyunsaturated fatty acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c350d6bcaabf573451dccf47e9bb2c
https://doi.org/10.1101/2022.09.01.506096
https://doi.org/10.1101/2022.09.01.506096