Novel hepatitis B virus reverse transcriptase mutations in patients with sustained viremia despite long-term tenofovir treatment

Autor: Anni Winckelmann, Ulrik Fahnøe, Priyanka Shukla Bajpai, Magnus Illum Dalegaard, Andreas Lundh, Lene Ryom, Jens Bukh, Nina Weis

Publikováno v: University of Southern Denmark
Winckelmann, A, Fahnoe, U, Bajpai, P, Dalegaard, M I, Lundh, A, Ryom, L, Bukh, J & Weis, N 2021, ' Novel Hepatitis B Virus Reverse Transcriptase Mutations in Patients With Sustained Viremia Despite Long-Term Tenofovir Treatment ', Hepatology, vol. 74, no. Suppl. 1, pp. 488A-489A . < https://aasldpubs.onlinelibrary.wiley.com/doi/epdf/10.1002/hep.32188 >
Winckelmann, A, Fahnøe, U, Bajpai, P S, Dalegaard, M I, Lundh, A, Ryom, L, Bukh, J & Weis, N 2022, ' Novel hepatitis B virus reverse transcriptase mutations in patients with sustained viremia despite long-term tenofovir treatment ', Journal of Clinical Virology, vol. 150-151, 105159 . https://doi.org/10.1016/j.jcv.2022.105159

Background: Chronic hepatitis B virus (HBV) treatment consists of nucleos(t)ide analogues to suppress viral replication. The HBV inhibitor tenofovir has a high barrier to resistance, however, evidence of virus-escape is emerging. This study investiga

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https://pubmed.ncbi.nlm.nih.gov/35487093

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