Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tenna V. Henriksen"'
Autor:
Tenna V. Henriksen, Thomas Reinert, Emil Christensen, Himanshu Sethi, Karin Birkenkamp‐Demtröder, Mikail Gögenur, Ismail Gögenur, Bernhard G. Zimmermann, The IMPROVE Study Group, Lars Dyrskjøt, Claus L. Andersen
Publikováno v:
Molecular Oncology, Vol 14, Iss 8, Pp 1670-1679 (2020)
Detection of circulating tumor DNA (ctDNA) post‐treatment is an emerging marker of residual disease. ctDNA constitutes only a minor fraction of the cell‐free DNA (cfDNA) circulating in cancer patients, complicating ctDNA detection. This is exacer
Externí odkaz:
https://doaj.org/article/1a0853f72d514abf8dadcf4dce6648a3
Autor:
Nadia Øgaard, Thomas Reinert, Tenna V. Henriksen, Amanda Frydendahl, Emilie Aagaard, Mai-Britt W. Ørntoft, Marie Ø. Larsen, Anders R. Knudsen, Frank V. Mortensen, Claus L. Andersen
Publikováno v:
Øgaard, N, Reinert, T, Henriksen, T V, Frydendahl, A, Aagaard, E, Ørntoft, M B W, Larsen, M, Knudsen, A R, Mortensen, F V & Andersen, C L 2022, ' Tumour-agnostic circulating tumour DNA analysis for improved recurrence surveillance after resection of colorectal liver metastases : A prospective cohort study ', European Journal of Cancer, vol. 163, pp. 163-176 . https://doi.org/10.1016/j.ejca.2021.12.026
Purpose: Nearly 50% of patients recur within two years after curatively intended resection of colorectal cancer liver metastasis (CRLM). The optimal surveillance strategy is unknown due to the lack of evidence. Here, we explored the potential for imp
Autor:
Lene Hjerrild Iversen, Claus L. Andersen, Derrick Renner, Thomas Reinert, Ole Thorlacius-Ussing, Desamparados Roda, Tenna V Henriksen, Alexey Aleshin, Andrés Cervantes, Noelia Tarazona, Per Vadgaard Andersen, Shruti Sharma, Susana Roselló, J.A. Carbonell-Asins, Dina Hafez, Anders Husted Madsen, Uffe S. Løve, Kåre Andersson Gotschalck, Amanda Frydendahl, Marisol Huerta, F. Gimeno-Valiente, Himanshu Sethi
Publikováno v:
Henriksen, T V, Tarazona, N, Frydendahl, A, Reinert, T, Gimeno-Valiente, F, Carbonell-Asins, J A, Sharma, S, Renner, D, Hafez, D, Roda, D, Huerta, M, Roselló, S, Madsen, A H, Løve, U S, Andersen, P V, Thorlacius-Ussing, O, Iversen, L H, Gotschalck, K A, Sethi, H, Aleshin, A, Cervantes, A & Andersen, C L 2022, ' Circulating Tumor DNA in Stage III Colorectal Cancer, beyond Minimal Residual Disease Detection, toward Assessment of Adjuvant Therapy Efficacy and Clinical Behavior of Recurrences ', Clinical Cancer Research, vol. 28, no. 3, pp. 507-517 . https://doi.org/10.1158/1078-0432.CCR-21-2404
Clinical cancer research : an official journal of the American Association for Cancer Research
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Clinical cancer research : an official journal of the American Association for Cancer Research
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Purpose: Sensitive methods for risk stratification, monitoring therapeutic efficacy, and early relapse detection may have a major impact on treatment decisions and patient management for stage III colorectal cancer patients. Beyond assessing the pred
Autor:
Tenna V Henriksen, Simon O Drue, Amanda Frydendahl, Christina Demuth, Mads H Rasmussen, Thomas Reinert, Jakob S Pedersen, Claus L Andersen
Publikováno v:
Henriksen, T V, Drue, S O, Frydendahl, A, Demuth, C, Rasmussen, M H, Reinert, T, Pedersen, J S & Andersen, C L 2022, ' Error Characterization and Statistical Modeling Improves Circulating Tumor DNA Detection by Droplet Digital PCR ', Clinical Chemistry, vol. 68, no. 5, pp. 657-667 . https://doi.org/10.1093/clinchem/hvab274
Background Droplet digital PCR (ddPCR) is a widely used and sensitive application for circulating tumor DNA (ctDNA) detection. As ctDNA is often found in low abundance, methods to separate low-signal readouts from noise are necessary. We aimed to cha
Autor:
Mai-Britt Worm Ørntoft, Ib Jarle Christensen, Hans Jørgen Nielsen, Tenna V Henriksen, Thomas Reinert, Sarah Østrup Jensen, Linnea Ferm, Nadia Øgaard, Ole Halfdan Larsen, Claus L. Andersen
Publikováno v:
Ørntoft, M-B W, Jensen, S Ø, Øgaard, N, Henriksen, T V, Ferm, L, Christensen, I J, Reinert, T, Larsen, O H, Nielsen, H J & Andersen, C L 2021, ' Age-stratified reference intervals unlock the clinical potential of circulating cell-free DNA as a biomarker of poor outcome for healthy individuals and patients with colorectal cancer ', International Journal of Cancer, vol. 148, no. 7, pp. 1665-1675 . https://doi.org/10.1002/ijc.33434
International Journal of Cancer
Ørntoft, M B W, Jensen, S Ø, Øgaard, N, Henriksen, T V, Ferm, L, Christensen, I J, Reinert, T, Larsen, O H, Nielsen, H J & Andersen, C L 2021, ' Age-stratified reference intervals unlock the clinical potential of circulating cell-free DNA as a biomarker of poor outcome for healthy individuals and patients with colorectal cancer ', International Journal of Cancer, pp. 1665-1675 . https://doi.org/10.1002/ijc.33434
International Journal of Cancer
Ørntoft, M B W, Jensen, S Ø, Øgaard, N, Henriksen, T V, Ferm, L, Christensen, I J, Reinert, T, Larsen, O H, Nielsen, H J & Andersen, C L 2021, ' Age-stratified reference intervals unlock the clinical potential of circulating cell-free DNA as a biomarker of poor outcome for healthy individuals and patients with colorectal cancer ', International Journal of Cancer, pp. 1665-1675 . https://doi.org/10.1002/ijc.33434
Circulating cell‐free DNA (cfDNA) has spurred much interest as a biomarker in oncology. However, inter‐ and intra‐individual cfDNA levels vary greatly. Consequently, in order to base clinical decisions on cfDNA measurements, normal reference in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa7779f1c4b2bae995bd0cc9d363708
https://pure.au.dk/portal/da/publications/agestratified-reference-intervals-unlock-the-clinical-potential-of-circulating-cellfree-dna-as-a-biomarker-of-poor-outcome-for-healthy-individuals-and-patients-with-colorectal-cancer(e8da8c89-4f6d-4edd-9cdc-3bb0ba56127b).html
https://pure.au.dk/portal/da/publications/agestratified-reference-intervals-unlock-the-clinical-potential-of-circulating-cellfree-dna-as-a-biomarker-of-poor-outcome-for-healthy-individuals-and-patients-with-colorectal-cancer(e8da8c89-4f6d-4edd-9cdc-3bb0ba56127b).html
Autor:
J.A. Carbonell-Asins, Marisol Huerta, Susana Roselló, Lene Hjerrild Iversen, Claus L. Andersen, Ole Thorlacius-Ussing, Tenna V Henriksen, Alexey Aleshin, Andrés Cervantes, Uffe S. Løve, Kåre Andersson Gotschalck, Noelia Tarazona, Thomas Reinert, Shruti Sharma, Amanda Frydendahl, Derrick Renner, Himanshu Sethi, Desamparados Roda
Publikováno v:
Henriksen, T V V, Tarazona, N, Frydendahl, A, Reinert, T, Carbonell-Asins, J A, Sharma, S, Renner, D, Roda, D, Huerta, M, Rosello, S, Gotschalck, K A, Iversen, L H, Love, U S, Thorlacius-Ussing, O, Sethi, H, Aleshin, A, Cervantes, A & Andersen, C L 2021, ' Serial circulating tumor DNA analysis to assess recurrence risk, benefit of adjuvant therapy, growth rate and early relapse detection in stage III colorectal cancer patients ', Journal of Clinical Oncology, vol. 39, no. Suppl. 15, 3540 . https://doi.org/10.1200/JCO.2021.39.15suppl.3540
3540 Background: Challenges in the postoperative management of stage III colorectal cancer include: 1) selection of high-risk patients for adjuvant chemotherapy (ACT), 2) lack of markers to assess ACT efficacy, 3) assessment of recurrence risk after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea9df70c61807d6f8933ef2eba3e6b4
https://vbn.aau.dk/da/publications/6d1b9bc2-00a9-4742-93ec-9400d179fc18
https://vbn.aau.dk/da/publications/6d1b9bc2-00a9-4742-93ec-9400d179fc18
Publikováno v:
Reinert, T, Henriksen, T V, Aleshin, A, Zimmermann, B & Andersen, C L 2021, ' Plasma-only ctDNA-guided MRD detection in patients with CRC : letter ', Clinical Cancer Research, vol. 27, no. 23, pp. 6613 . https://doi.org/10.1158/1078-0432.CCR-21-2735
Below we express our concerns about the article authored by Parikh and colleagues, investigating the performance of a tumor-uninformed ctDNA assay (Guardant Health, Reveal) for MRD detection in patients with colorectal cancer ([1][1]). The authors pr
Autor:
Lene Hjerrild Iversen, Shruti Sharma, N. Tarazona, Svetlana Shchegrova, Thomas Reinert, Andrés Cervantes, Anders Husted Madsen, Antony Tin, J.A. Carbonell-Asins, M. Huerta, Alexey Aleshin, Tenna V Henriksen, Claus L. Andersen, Susana Roselló, Kåre Andersson Gotschalck, Bernhard Zimmermann, Himanshu Sethi, H.-T. Wu, Desamparados Roda
Publikováno v:
Annals of Oncology. 31:S419-S420
Autor:
Thomas Reinert, Katrine Stribolt, Zoe June Assaf, Lene Hjerrild Iversen, Matthew Rabinowitz, Ryan Swenerton, Ramya Srinivasan, Samantha Navarro, Lars Dyrskjøt, Claus L. Andersen, Tenna V Henriksen, Anne-Sofie Kannerup, Søren Vang, Alexander Olson, Shruti Goel, Alexey Aleshin, Michael Knudsen, Scott Dashner, Styrmir Sigurjonsson, Mustafa Balcioglu, Emil Christensen, Anders Husted Madsen, Cheng-Ho Jimmy Lin, Raheleh Salari, Paul Billings, Himanshu Sethi, Søren Krag, Mads Rasmussen, Søren Laurberg, Shruti Sharma, Bernhard Zimmermann, Svetlana Shchegrova, Amanda Frydendahl Boll Johansen, Antony Tin, Dina Hafez, Hsin-Ta Wu, Iver Nordentoft, Kåre Gotschalck Sunesen
Publikováno v:
Reinert, T, Henriksen, T V, Christensen, E, Sharma, S, Salari, R, Sethi, H, Knudsen, M, Nordentoft, I, Wu, H-T, Tin, A S, Heilskov Rasmussen, M, Vang, S, Shchegrova, S, Frydendahl Boll Johansen, A, Srinivasan, R, Assaf, Z, Balcioglu, M, Olson, A, Dashner, S, Hafez, D, Navarro, S, Goel, S, Rabinowitz, M, Billings, P, Sigurjonsson, S, Dyrskjøt, L, Swenerton, R, Aleshin, A, Laurberg, S, Husted Madsen, A, Kannerup, A-S, Stribolt, K, Palmelund Krag, S, Iversen, L H, Gotschalck Sunesen, K, Lin, C-H J, Zimmermann, B G & Lindbjerg Andersen, C 2019, ' Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer ', JAMA Oncology, vol. 5, no. 8, pp. 1124-1131 . https://doi.org/10.1001/jamaoncol.2019.0528
Importance: Novel sensitive methods for detection and monitoring of residual disease can improve postoperative risk stratification with implications for patient selection for adjuvant chemotherapy (ACT), ACT duration, intensity of radiologic surveill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59acf069d0b5229abc11521aab11d94
https://pure.au.dk/ws/files/197692926/jamaoncology_reinert_2019_oi_190019.pdf
https://pure.au.dk/ws/files/197692926/jamaoncology_reinert_2019_oi_190019.pdf
Autor:
Lene Hjerrild Iversen, Ole Thorlacius-Ussing, Tenna V Henriksen, Marisol Huerta, Alexey Aleshin, Claus L. Andersen, Derrick Renner, Susana Roselló, Anders Husted Madsen, Thomas Reinert, Per Vadgaard Andersen, Andrés Cervantes, Shruti Sharma, Himanshu Sethi, Uffe S. Løve, Kåre Andersson Gotschalck, J.A. Carbonell-Asins, N. Tarazona, Desamparados Roda
Publikováno v:
Henriksen, T V, Tarazona, N, Reinert, T, Carbonell-Asins, J A, Renner, D, Sharma, S, Roda, D, Huerta, M, Roselló, S, Iversen, L H, Gotschalck, K A, Madsen, A H, Andersen, P V, Thorlacius-Ussing, O, Løve, U S, Sethi, H, Aleshin, A, Cervantes, A & Andersen, C L 2021, ' Circulating tumor DNA analysis for assessment of recurrence risk, benefit of adjuvant therapy, and early relapse detection after treatment in colorectal cancer patients. ', Journal of Clinical Oncology, vol. 39, no. 3 Suppl., pp. 11 . https://doi.org/10.1200/JCO.2021.39.3_suppl.11
Henriksen V, T, Tarazona, N, Reinert, T, Carbonell-Asins, J A, Renner, D, Sharma, S, Roda, D, Huerta, M, Rosello, S, Iversen, L H, Gotschalck, K A, Madsen, A H, Andersen, P V, Thorlacius-Ussing, O, Love, U S, Sethi, H, Aleshin, A, Cervantes, A & Andersen, C L 2021, ' Circulating tumor DNA analysis for assessment of recurrence risk, benefit of adjuvant therapy, and early relapse detection after treatment in colorectal cancer patients ', Journal of Clinical Oncology, vol. 39, no. Suppl. 3, pp. 11-11 . < https://ascopubs.org/doi/abs/10.1200/JCO.2021.39.3_suppl.11 >
Henriksen V, T, Tarazona, N, Reinert, T, Carbonell-Asins, J A, Renner, D, Sharma, S, Roda, D, Huerta, M, Rosello, S, Iversen, L H, Gotschalck, K A, Madsen, A H, Andersen, P V, Thorlacius-Ussing, O, Love, U S, Sethi, H, Aleshin, A, Cervantes, A & Andersen, C L 2021, ' Circulating tumor DNA analysis for assessment of recurrence risk, benefit of adjuvant therapy, and early relapse detection after treatment in colorectal cancer patients ', Journal of Clinical Oncology, vol. 39, no. Suppl. 3, pp. 11-11 . < https://ascopubs.org/doi/abs/10.1200/JCO.2021.39.3_suppl.11 >
11 Background: Timely detection of recurrence, as well as identification of patients at high risk of recurrence after surgery and after completion of adjuvant therapy, are major challenges in the treatment of colorectal cancer (CRC). Postsurgical cir