Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Tengqian Sun"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/729f5c7d933b400ea40caf8b6501371a
Publikováno v:
ACS Central Science, Vol 7, Iss 12, Pp 2009-2020 (2021)
Externí odkaz:
https://doaj.org/article/1157346d751749abbdb598b2fb113fae
Autor:
Xin Zhou, Yanghao Zhong, Olivia Molinar-Inglis, Maya T. Kunkel, Mingyuan Chen, Tengqian Sun, Jiao Zhang, John Y.-J. Shyy, JoAnn Trejo, Alexandra C. Newton, Jin Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The role of mTORC1 at the lysosome is well established, but mTORC1 is known to be active in other cellular locations. Here, the authors develop Akt-STOPS to inhibit Akt specifically in the nucleus and identify a new regulatory mode for mTORC1 distinc
Externí odkaz:
https://doaj.org/article/328e1750a1694424bd2ac2b272c85bfe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Abstract Genetically encoded Förster Resonance Energy Transfer (FRET)-based biosensors are powerful tools to illuminate spatiotemporal regulation of cell signaling in living cells, but the utility of the red spectrum for biosensing was limited due t
Externí odkaz:
https://doaj.org/article/60e52827acdd49bbad631b9bd047a4e2
Autor:
Jeremy N. Rich, Qi Xie, Stephen C. Mack, Tao Huan, Hu Cang, J. Mark Brown, Paul S. Mischel, Andrew E. Sloan, Junfeng Bi, Derrick Lee, Linjie Zhao, Zhen Dong, Guoxin Zhang, Zhe Zhu, Qing Ye, Xiuxing Wang, Briana C. Prager, Li Jiang, Shruti Bhargava, Deguan Lv, Megan Wolf, Qiulian Wu, Anthony D. Gromovsky, Tengqian Sun, Leo J.Y. Kim, Reilly L. Kidwell, Ryan C. Gimple
Glioblastoma ranks among the most aggressive and lethal of all human cancers. Functionally defined glioma stem cells (GSC) contribute to this poor prognosis by driving therapeutic resistance and maintaining cellular heterogeneity. To understand the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::017cd35c1fa2651dd17a65cd82a1e4bb
https://doi.org/10.1158/2159-8290.c.6548195.v1
https://doi.org/10.1158/2159-8290.c.6548195.v1
Autor:
Jeremy N. Rich, Qi Xie, Stephen C. Mack, Tao Huan, Hu Cang, J. Mark Brown, Paul S. Mischel, Andrew E. Sloan, Junfeng Bi, Derrick Lee, Linjie Zhao, Zhen Dong, Guoxin Zhang, Zhe Zhu, Qing Ye, Xiuxing Wang, Briana C. Prager, Li Jiang, Shruti Bhargava, Deguan Lv, Megan Wolf, Qiulian Wu, Anthony D. Gromovsky, Tengqian Sun, Leo J.Y. Kim, Reilly L. Kidwell, Ryan C. Gimple
Supplementary Methods 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b946addf979fc82ed3af498a5bc5d241
https://doi.org/10.1158/2159-8290.22536647.v1
https://doi.org/10.1158/2159-8290.22536647.v1
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
Genetically encoded Förster Resonance Energy Transfer (FRET)-based biosensors are powerful tools to illuminate spatiotemporal regulation of cell signaling in living cells, but the utility of the red spectrum for biosensing was limited due to a lack
Publikováno v:
The FASEB Journal. 35
Autor:
Stephen C. Mack, Leo J.Y. Kim, Hu Cang, Zhen Dong, Deguan Lv, Jeremy N. Rich, Megan E Wolf, Reilly L. Kidwell, Qi Xie, Tao Huan, Qing Ye, J. Mark Brown, Xiuxing Wang, Tengqian Sun, Junfeng Bi, Guoxin Zhang, Derrick Lee, Ryan C. Gimple, Andrew E. Sloan, Zhe Zhu, Shruti Bhargava, Anthony D. Gromovsky, Linjie Zhao, Briana C. Prager, Li Jiang, Qiulian Wu, Paul S. Mischel
Publikováno v:
Cancer Discovery. 9:1248-1267
Glioblastoma ranks among the most aggressive and lethal of all human cancers. Functionally defined glioma stem cells (GSC) contribute to this poor prognosis by driving therapeutic resistance and maintaining cellular heterogeneity. To understand the m
Autor:
Alexandra C. Newton, Yanghao Zhong, Xin Zhou, Olivia Molinar-Inglis, Mingyuan Chen, Jiao Zhang, John Y.-J. Shyy, Maya T. Kunkel, Tengqian Sun, Jin Zhang, JoAnn Trejo
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol 11, iss 1
The mechanistic target of rapamycin complex 1 (mTORC1) integrates growth, nutrient and energy status cues to control cell growth and metabolism. While mTORC1 activation at the lysosome is well characterized, it is not clear how this complex is regula