Management and outcome of patients with Wilms’ Tumour (Nephroblastoma) at the Moi Teaching and Referral Hospital, Eldoret, Kenya

Autor: Tenge, CN, Were, PA, Aluoch, LH, Wekesa, JW, Patel, K, Kuremu, RT

Publikováno v: East African Medical Journal; Vol 89, No 4 (2012); 121-127

Background: Wilms’ tumour is a common malignant neoplasm of the kidney and is ranked among the top six solid tumours in children in Kenya. Despite its rapid growth and therefore debilitating effects on its victims, it is one tumour that has shown g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=78975075580c::771111bc99829db713d54471af681bd8
https://www.ajol.info/index.php/eamj/article/view/89598

Human leukocyte antigen-DQA1*04:01 and rs2040406 variants are associated with elevated risk of childhood Burkitt lymphoma.

Autor: Liu Z; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Luo Y; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.; Center for Data Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Rheumatology, Immunology, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kirimunda S; College of Health Sciences, Makerere University, Kampala, Uganda., Verboom M; Institute of Transfusion Medicine and Transplant Engineering, Hanover, Germany., Onabajo OO; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Gouveia MH; Center for Research on Genomics & Global Health, NHGRI, National Institutes of Health, Bethesda, MD, USA., Ogwang MD; St. Mary's Hospital, Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Kerchan P; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; Kuluva Hospital, Arua, Uganda., Reynolds SJ; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Tenge CN; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; Moi University College of Health Sciences, Eldoret, Kenya., Were PA; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya., Kuremu RT; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; Moi University College of Health Sciences, Eldoret, Kenya., Wekesa WN; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; Moi University College of Health Sciences, Eldoret, Kenya., Masalu N; Bugando Medical Center, Mwanza, Tanzania., Kawira E; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; Shirati Health, Education, and Development Foundation, Shirati, Tanzania., Kinyera T; St. Mary's Hospital, Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Otim I; St. Mary's Hospital, Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Legason ID; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; Kuluva Hospital, Arua, Uganda., Nabalende H; St. Mary's Hospital, Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Dhudha H; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; Shirati Health, Education, and Development Foundation, Shirati, Tanzania., Ayers LW; Department of Pathology, The Ohio State University, Columbus, OH, USA., Bhatia K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Goedert JJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Cole N; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Luo W; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Liu J; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Manning M; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Hicks B; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Prokunina-Olsson L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Chagaluka G; Departments of Pediatrics and Surgery, Kamuzu University of Health Sciences (formerly College of Medicine), University of Malawi, Blantyre, Malawi., Johnston WT; Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK., Mutalima N; Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK.; Cancer Epidemiology Unit, University of Oxford, Oxford, UK., Borgstein E; Departments of Pediatrics and Surgery, Kamuzu University of Health Sciences (formerly College of Medicine), University of Malawi, Blantyre, Malawi., Liomba GN; Departments of Pediatrics and Surgery, Kamuzu University of Health Sciences (formerly College of Medicine), University of Malawi, Blantyre, Malawi., Kamiza S; Departments of Pediatrics and Surgery, Kamuzu University of Health Sciences (formerly College of Medicine), University of Malawi, Blantyre, Malawi., Mkandawire N; Departments of Pediatrics and Surgery, Kamuzu University of Health Sciences (formerly College of Medicine), University of Malawi, Blantyre, Malawi., Mitambo C; National Health Sciences Research Committee, Research Department, Ministry of Health, Lilongwe, Malawi., Molyneux EM; Departments of Pediatrics and Surgery, Kamuzu University of Health Sciences (formerly College of Medicine), University of Malawi, Blantyre, Malawi., Newton R; Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK., Hsing AW; Stanford Cancer Institute, Stanford University, Stanford, CA, USA., Mensah JE; University of Ghana Medical School, Accra, Ghana., Adjei AA; University of Ghana Medical School, Accra, Ghana., Hutchinson A; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Yeager M; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Blasczyk R; Institute of Transfusion Medicine and Transplant Engineering, Hanover, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA., Raychaudhuri S; Center for Data Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Rheumatology, Immunology, and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mbulaiteye SM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. mbulaits@mail.nih.gov.

Publikováno v: Communications biology [Commun Biol] 2024 Jan 05; Vol. 7 (1), pp. 41. Date of Electronic Publication: 2024 Jan 05.

Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa.

Autor: Zhou W; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Fischer A; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany., Ogwang MD; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu, Uganda., Luo W; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Kerchan P; EMBLEM Study, Kuluva Hospital, Arua, Uganda., Reynolds SJ; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Tenge CN; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya., Were PA; EMBLEM Study, Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya., Kuremu RT; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya., Wekesa WN; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya., Masalu N; EMBLEM Study, Bugando Medical Center, Mwanza, Tanzania., Kawira E; EMBLEM Study, Shirati Health, Education, and Development Foundation, Shirati, Tanzania., Kinyera T; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Otim I; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Legason ID; EMBLEM Study, Kuluva Hospital, Arua, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Nabalende H; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Ayers LW; Department of Pathology, The Ohio State University, Columbus, OH, USA., Bhatia K; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA., Goedert JJ; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA., Gouveia MH; Center for Research on Genomics & Global Health, NHGRI, National Institutes of Health, Bethesda, MD, USA., Cole N; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Hicks B; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Jones K; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Hummel M; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Berlin, Germany.; Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, D-10117, Berlin, Germany., Schlesner M; Biomedical Informatics, Data Mining and Data Analytics, University of Augsburg, Augsburg, Germany., Chagaluka G; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Mutalima N; Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK.; Cancer Epidemiology Unit, University of Oxford, Oxford, UK., Borgstein E; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Liomba GN; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Kamiza S; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Mkandawire N; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Mitambo C; Research Department, Ministry of Health, P.O. Box 30377, Lilongwe 3, Malawi., Molyneux EM; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Newton R; Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK., Glaser S; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany., Kretzmer H; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany., Manning M; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Hutchinson A; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Hsing AW; Stanford Cancer Institute, Stanford University, Stanford, Palo Alto, CA, USA., Tettey Y; Department of Pathology, University of Ghana Medical School, College of Health Sciences, P.O. Box KB 52, Korle-Bu, Accra, Ghana., Adjei AA; Department of Pathology, University of Ghana Medical School, College of Health Sciences, P.O. Box KB 52, Korle-Bu, Accra, Ghana., Chanock SJ; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Siebert R; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany., Yeager M; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Prokunina-Olsson L; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA., Machiela MJ; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA., Mbulaiteye SM; Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA. mbulaits@mail.nih.gov.

Publikováno v: Nature communications [Nat Commun] 2023 Dec 06; Vol. 14 (1), pp. 8081. Date of Electronic Publication: 2023 Dec 06.

Burkitt lymphoma risk shows geographic and temporal associations with Plasmodium falciparum infections in Uganda, Tanzania, and Kenya.

Autor: Broen K; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109.; Center for Social Epidemiology and Population Health, School of Public Health, University of Michigan, Ann Arbor, MI 48109., Dickens J; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109.; Center for Social Epidemiology and Population Health, School of Public Health, University of Michigan, Ann Arbor, MI 48109., Trangucci R; Department of Statistics, University of Michigan, Ann Arbor, MI 48109., Ogwang MD; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu.; African Field Epidemiology Network, Kampala, Uganda., Tenge CN; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.; Academic Model Providing Access To Healthcare, Eldoret, Kenya., Masalu N; EMBLEM Study, Bugando Medical Center, Mwanza, Tanzania., Reynolds SJ; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892., Kawira E; Epidemiology of Burkitt Lymphoma in East-African Children and Minors (EMBLEM) Study, Shirati Health and Educational Foundation, Shirati, Tanzania., Kerchan P; African Field Epidemiology Network, Kampala, Uganda.; EMBLEM Study, Kuluva Hospital, Arua, Uganda., Were PA; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.; Academic Model Providing Access To Healthcare, Eldoret, Kenya., Kuremu RT; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.; Academic Model Providing Access To Healthcare, Eldoret, Kenya., Wekesa WN; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.; Academic Model Providing Access To Healthcare, Eldoret, Kenya., Kinyera T; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu.; African Field Epidemiology Network, Kampala, Uganda., Otim I; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu.; African Field Epidemiology Network, Kampala, Uganda., Legason ID; African Field Epidemiology Network, Kampala, Uganda.; EMBLEM Study, Kuluva Hospital, Arua, Uganda., Nabalende H; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu.; African Field Epidemiology Network, Kampala, Uganda., Buller ID; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.; Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892., Ayers LW; Department of Pathology,The Ohio State University, Columbus, OH 43210., Bhatia K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892., Biggar RJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892., Goedert JJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892., Wilson ML; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109., Mbulaiteye SM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892., Zelner J; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109.; Center for Social Epidemiology and Population Health, School of Public Health, University of Michigan, Ann Arbor, MI 48109.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Jan 10; Vol. 120 (2), pp. e2211055120. Date of Electronic Publication: 2023 Jan 03.

Inverse association of falciparum positivity with endemic Burkitt lymphoma is robust in analyses adjusting for pre-enrollment malaria in the EMBLEM case-control study.

Autor: Peprah S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Infections and Immunoepidemiology Branch, 9609 Medical Center Dr, Rm. 6E-118, MSC 3330, Bethesda, MD, 20892, USA., Ogwang MD; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu & African Field Epidemiology Network, Kampala, Uganda., Kerchan P; EMBLEM Study, Kuluva Hospital, Arua & African Field Epidemiology Network, Kampala, Uganda., Reynolds SJ; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Tenge CN; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.; Moi Teaching and Referral Hospital (MTRH), Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya., Were PA; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.; Moi Teaching and Referral Hospital (MTRH), Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya., Kuremu RT; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.; Moi Teaching and Referral Hospital (MTRH), Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya., Wekesa WN; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya.; Moi Teaching and Referral Hospital (MTRH), Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya., Masalu N; EMBLEM Study, Bugando Medical Center, Mwanza, Tanzania., Kawira E; EMBLEM Study, Shirati Health and Educational Foundation, Shirati, Tanzania., Otim I; EMBLEM Study, St. Mary's Hospital, Lacor, Gulu & African Field Epidemiology Network, Kampala, Uganda., Legason ID; EMBLEM Study, Kuluva Hospital, Arua & African Field Epidemiology Network, Kampala, Uganda., Ayers LW; Department of Pathology, The Ohio State University, Columbus, OH, USA., Bhatia K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Infections and Immunoepidemiology Branch, 9609 Medical Center Dr, Rm. 6E-118, MSC 3330, Bethesda, MD, 20892, USA., Goedert JJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Infections and Immunoepidemiology Branch, 9609 Medical Center Dr, Rm. 6E-118, MSC 3330, Bethesda, MD, 20892, USA., Pfeiffer RM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Infections and Immunoepidemiology Branch, 9609 Medical Center Dr, Rm. 6E-118, MSC 3330, Bethesda, MD, 20892, USA., Mbulaiteye SM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Infections and Immunoepidemiology Branch, 9609 Medical Center Dr, Rm. 6E-118, MSC 3330, Bethesda, MD, 20892, USA. mbulaits@mail.nih.gov.

Publikováno v: Infectious agents and cancer [Infect Agent Cancer] 2021 Jun 07; Vol. 16 (1), pp. 40. Date of Electronic Publication: 2021 Jun 07.