Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Teng-Wei Zhu"'
Autor:
Lin-Kun An, Lian-Quan Gu, Teng-Wei Zhu, Jian-Wen Chen, Le-Mao Yu, Qian Yu, Zhi-Shu Huang, Hui Yang
Publikováno v:
European Journal of Medicinal Chemistry. 152:195-207
Our previous studies reveal that indolizinoquinolinedione scaffold is a base to develop novel DNA topoisomerase IB (TOP1) catalytic inhibitors. In this work, twenty-three novel indolizinoquinolinedione derivatives were synthesized. TOP1-mediated rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22f4064f31c75a0170e356d8b3d5b3d
https://doi.org/10.1016/j.ejmech.2018.04.040
https://doi.org/10.1016/j.ejmech.2018.04.040
Autor:
Hao-Wen Wang, Lin-Kun An, Jian-Wen Chen, Le-Mao Yu, Ding Li, Zhi-Shu Huang, Lei Shi, Lu-Xia Wang, Hui Yang, Teng-Wei Zhu, Lian-Quan Gu
Publikováno v:
European journal of medicinal chemistry. 127
In our previous research, 9-bromo indolizinoquinoline-5,12-dione 1 has been found to be a good anti-MRSA agent. However, it had very low bioavailability in vivo possibly due to its low solubility in water. In order to obtain the derivatives with high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b380251e125a012d525eecc49c7b640b
https://pubmed.ncbi.nlm.nih.gov/28061346
https://pubmed.ncbi.nlm.nih.gov/28061346
Publikováno v:
MATEC Web of Conferences; 8/5/2018, Vol. 186, p1-6, 6p