The Difference in Serum Metabolomic Profiles between the Good and Poor Outcome Groups at 3 Months in the Early and Late Phases of Aneurysmal Subarachnoid Hemorrhage.

Autor: Orban B; Department of Neurosurgery, Medical School, University of Pecs, 7632 Pecs, Hungary., Tengölics R; Metabolomics Lab, Biological Research Centre, Hungarian Research Network, 6726 Szeged, Hungary.; Core Facilities, Biological Research Centre, Hungarian Research Network, 6726 Szeged, Hungary.; Hungarian Centre of Excellence for Molecular Medicine-Biological Research Centre Metabolic Systems Biology Lab, 6726 Szeged, Hungary., Zavori L; Emergency Department, Saudi German Hospital, Dubai 391093, United Arab Emirates., Simon D; Department of Immunology and Biotechnology, Medical School, University of Pecs, 7632 Pecs, Hungary., Erdo-Bonyar S; Department of Immunology and Biotechnology, Medical School, University of Pecs, 7632 Pecs, Hungary., Molnar T; Department of Anaesthesiology and Intensive Care, Medical School, University of Pecs, 7632 Pecs, Hungary., Schwarcz A; Department of Neurosurgery, Medical School, University of Pecs, 7632 Pecs, Hungary., Csecsei P; Department of Neurosurgery, Medical School, University of Pecs, 7632 Pecs, Hungary.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 15; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 15.

The metabolic domestication syndrome of budding yeast.

Autor: Tengölics R; Hungarian Centre of Excellence for Molecular Medicine - Biological Research Centre Metabolic Systems Biology Lab, Szeged 6726, Hungary.; Synthetic and System Biology Unit, National Laboratory of Biotechnology, Institute of Biochemistry, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary.; Metabolomics Lab, Core facilities, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary., Szappanos B; Hungarian Centre of Excellence for Molecular Medicine - Biological Research Centre Metabolic Systems Biology Lab, Szeged 6726, Hungary.; Synthetic and System Biology Unit, National Laboratory of Biotechnology, Institute of Biochemistry, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary.; Department of Biotechnology, University of Szeged, Szeged 6726, Hungary., Mülleder M; Charité Universitätsmedizin, Core Facility High-Throughput Mass Spectrometry, Berlin 10117, Germany., Kalapis D; Hungarian Centre of Excellence for Molecular Medicine - Biological Research Centre Metabolic Systems Biology Lab, Szeged 6726, Hungary.; Synthetic and System Biology Unit, National Laboratory of Biotechnology, Institute of Biochemistry, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary., Grézal G; Hungarian Centre of Excellence for Molecular Medicine - Biological Research Centre Metabolic Systems Biology Lab, Szeged 6726, Hungary.; Synthetic and System Biology Unit, National Laboratory of Biotechnology, Institute of Biochemistry, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary., Sajben C; Metabolomics Lab, Core facilities, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary., Agostini F; Department of Biochemistry, Charité Universitätsmedizin, Berlin 10117, Germany., Mokochinski JB; Synthetic and System Biology Unit, National Laboratory of Biotechnology, Institute of Biochemistry, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary., Bálint B; Institute of Biochemistry, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary., Nagy LG; Institute of Biochemistry, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary., Ralser M; Department of Biochemistry, Charité Universitätsmedizin, Berlin 10117, Germany.; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, United Kingdom., Papp B; Hungarian Centre of Excellence for Molecular Medicine - Biological Research Centre Metabolic Systems Biology Lab, Szeged 6726, Hungary.; Synthetic and System Biology Unit, National Laboratory of Biotechnology, Institute of Biochemistry, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary.; National Laboratory for Health Security, Biological Research Centre, Hungarian Research Network, Szeged 6726, Hungary.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Mar 12; Vol. 121 (11), pp. e2313354121. Date of Electronic Publication: 2024 Mar 08.

Chloroplast phosphate transporter CrPHT4-7 regulates phosphate homeostasis and photosynthesis in Chlamydomonas.

Autor: Tóth D; Institute of Plant Biology, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary.; Doctoral School of Biology, University of Szeged, H-6722 Szeged, Hungary., Kuntam S; Institute of Plant Biology, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary., Ferenczi Á; Institute of Molecular Plant Sciences, School of Biological Sciences, King's Buildings, University of Edinburgh, Edinburgh EH9 3BF, UK., Vidal-Meireles A; Institute of Plant Biology, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary., Kovács L; Institute of Plant Biology, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary., Wang L; Department of Molecular Biology, Princeton University, Lewis Thomas Laboratory, Princeton, NJ 08544, USA., Sarkadi Z; Institute of Biochemistry, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary.; Hungarian Centre of Excellence for Molecular Medicine-Biological Research Centre Metabolic Systems Biology Research Group, H-6726 Szeged, Hungary., Migh E; Institute of Biochemistry, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary., Szentmihályi K; Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, H-1117 Budapest, Hungary., Tengölics R; Hungarian Centre of Excellence for Molecular Medicine-Biological Research Centre Metabolic Systems Biology Research Group, H-6726 Szeged, Hungary.; Metabolomics Lab, Core Facilities, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary., Neupert J; Max Planck Institute of Molecular Plant Physiology, D-14476 Potsdam-Golm, Germany., Bock R; Max Planck Institute of Molecular Plant Physiology, D-14476 Potsdam-Golm, Germany., Jonikas MC; Department of Molecular Biology, Princeton University, Lewis Thomas Laboratory, Princeton, NJ 08544, USA.; Howard Hughes Medical Institute, Princeton University, Lewis Thomas Laboratory, Princeton, NJ 08544, USA., Molnar A; Institute of Molecular Plant Sciences, School of Biological Sciences, King's Buildings, University of Edinburgh, Edinburgh EH9 3BF, UK., Tóth SZ; Institute of Plant Biology, HUN-REN Biological Research Centre, H-6726 Szeged, Hungary.

Publikováno v: Plant physiology [Plant Physiol] 2024 Feb 29; Vol. 194 (3), pp. 1646-1661.

Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan.

Autor: Correia-Melo C; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany. Electronic address: claramelo85@gmail.com., Kamrad S; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK., Tengölics R; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Eötvös Loránd Research Network, Szeged 6726, Hungary; HCEMM-BRC Metabolic Systems Biology Lab, Szeged 6726, Hungary., Messner CB; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Precision Proteomics Center, Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, 7265 Davos, Switzerland., Trebulle P; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Townsend S; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Jayasree Varma S; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Freiwald A; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany; Core Facility - High Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Heineike BM; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK; Quantitative Gene Expression Research Group, MRC London Institute of Medical Sciences (LMS), London W12 0HS, UK; Quantitative Gene Expression Research Group, Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London SW2 2AZ, UK., Campbell K; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK., Herrera-Dominguez L; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK., Kaur Aulakh S; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK., Szyrwiel L; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Yu JSL; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK., Zelezniak A; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden; Randall Centre for Cell & Molecular Biophysics, King's College London, New Hunt's House, Guy's Campus, London SE1 1UL, UK; Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius 10257, Lithuania., Demichev V; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Mülleder M; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK; Core Facility - High Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany., Papp B; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Eötvös Loránd Research Network, Szeged 6726, Hungary; HCEMM-BRC Metabolic Systems Biology Lab, Szeged 6726, Hungary., Alam MT; Department of Biology, College of Science, United Arab Emirates University, P.O.Box 15551, Al-Ain, United Arab Emirates., Ralser M; The Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK; Department of Biochemistry, Charité - Universitätsmedizin Berlin, 10117 Berlin, Germany; The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK. Electronic address: markus.ralser@charite.de.

Publikováno v: Cell [Cell] 2023 Jan 05; Vol. 186 (1), pp. 63-79.e21.

Stellaria media tea protects against diabetes-induced cardiac dysfunction in rats without affecting glucose tolerance.

Autor: Demján V; University of Szeged Albert Szent-Györgyi Medical School, Department of Biochemistry, Metabolic Diseases and Cell Signaling Group (MEDICS), 6720, Szeged, Dóm tér 9, Hungary.; University of Szeged, Interdisciplinary Centre for Natural Products, 6720, Szeged, Eötvös utca 6, Hungary.; University of Szeged, Interdisciplinary Centre of Excellence, 6720, Szeged, Dugonics tér 13, Hungary., Sója A; University of Szeged Albert Szent-Györgyi Medical School, Department of Biochemistry, Metabolic Diseases and Cell Signaling Group (MEDICS), 6720, Szeged, Dóm tér 9, Hungary.; University of Szeged, Interdisciplinary Centre for Natural Products, 6720, Szeged, Eötvös utca 6, Hungary.; University of Szeged, Interdisciplinary Centre of Excellence, 6720, Szeged, Dugonics tér 13, Hungary., Kiss T; University of Szeged, Interdisciplinary Centre for Natural Products, 6720, Szeged, Eötvös utca 6, Hungary.; University of Szeged, Faculty of Pharmacy, Department of Pharmacognosy, 6720, Szeged, Eötvös utca 6, Hungary., Fejes A; University of Szeged Albert Szent-Györgyi Medical School, Department of Biochemistry, Metabolic Diseases and Cell Signaling Group (MEDICS), 6720, Szeged, Dóm tér 9, Hungary.; University of Szeged, Interdisciplinary Centre for Natural Products, 6720, Szeged, Eötvös utca 6, Hungary.; University of Szeged, Interdisciplinary Centre of Excellence, 6720, Szeged, Dugonics tér 13, Hungary., Gausz FD; University of Szeged Albert Szent-Györgyi Medical School, Department of Biochemistry, Metabolic Diseases and Cell Signaling Group (MEDICS), 6720, Szeged, Dóm tér 9, Hungary.; University of Szeged, Interdisciplinary Centre for Natural Products, 6720, Szeged, Eötvös utca 6, Hungary.; University of Szeged, Interdisciplinary Centre of Excellence, 6720, Szeged, Dugonics tér 13, Hungary., Szűcs G; University of Szeged Albert Szent-Györgyi Medical School, Department of Biochemistry, Metabolic Diseases and Cell Signaling Group (MEDICS), 6720, Szeged, Dóm tér 9, Hungary.; University of Szeged, Interdisciplinary Centre for Natural Products, 6720, Szeged, Eötvös utca 6, Hungary.; University of Szeged, Interdisciplinary Centre of Excellence, 6720, Szeged, Dugonics tér 13, Hungary., Siska A; University of Szeged Albert Szent-Györgyi Medical School, Department of Laboratory Medicine, 6725, Szeged, Semmelweis utca 6, Hungary., Földesi I; University of Szeged Albert Szent-Györgyi Medical School, Department of Laboratory Medicine, 6725, Szeged, Semmelweis utca 6, Hungary., Tengölics R; Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Eötvös Loránd Research Network (ELKH), 6726, Temesvári krt. 62, Szeged, Hungary.; Hungarian Centre of Excellence for Molecular Medicine - Metabolic Systems Biology Lab, 6726, Temesvári krt. 62., Szeged, Hungary., Darula Z; Single Cell Omics Advanced Core Facility, Hungarian Centre of Excellence for Molecular Medicine (HCEMM), Szeged, Hungary.; Proteomics Research Group, Biological Research Centre, 6726, Szeged, Temesvári krt. 62, Hungary., Csupor D; University of Szeged, Interdisciplinary Centre for Natural Products, 6720, Szeged, Eötvös utca 6, Hungary.; University of Szeged, Faculty of Pharmacy, Department of Pharmacognosy, 6720, Szeged, Eötvös utca 6, Hungary.; University of Pécs, Faculty of Medicine, Institute for Translational Medicine, 7624, Pécs, Szigeti út 12, Hungary.; University of Szeged, Faculty of Pharmacy, Department of Clinical Pharmacy, 6725, Szeged, Szikra utca 8, Hungary., Pipicz M; University of Szeged Albert Szent-Györgyi Medical School, Department of Biochemistry, Metabolic Diseases and Cell Signaling Group (MEDICS), 6720, Szeged, Dóm tér 9, Hungary.; University of Szeged, Interdisciplinary Centre for Natural Products, 6720, Szeged, Eötvös utca 6, Hungary.; University of Szeged, Interdisciplinary Centre of Excellence, 6720, Szeged, Dugonics tér 13, Hungary., Csont T; University of Szeged Albert Szent-Györgyi Medical School, Department of Biochemistry, Metabolic Diseases and Cell Signaling Group (MEDICS), 6720, Szeged, Dóm tér 9, Hungary.; University of Szeged, Interdisciplinary Centre for Natural Products, 6720, Szeged, Eötvös utca 6, Hungary.; University of Szeged, Interdisciplinary Centre of Excellence, 6720, Szeged, Dugonics tér 13, Hungary.

Publikováno v: Journal of traditional and complementary medicine [J Tradit Complement Med] 2021 Aug 10; Vol. 12 (3), pp. 250-259. Date of Electronic Publication: 2021 Aug 10 (Print Publication: 2022).