Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Teneille Walker"'
Autor:
Laura Dishaw, Erin Yost, Xabier Arzuaga, April Luke, Andrew Kraft, Teneille Walker, Kris Thayer
Publikováno v:
Environment International, Vol 141, Iss , Pp 105736- (2020)
A key aspect of the systematic review process is study evaluation to understand the strengths and weaknesses of individual studies included in the review. The present manuscript describes the process currently being used by the Environmental Protecti
Externí odkaz:
https://doaj.org/article/715441712c1248c2a057f53e059bf4ac
Autor:
Paul Dent, Steven Grant, Paul B. Fisher, Christina Voelkel-Johnson, Roland Reinehr, Dieter Häussinger, Mohamed Rahmani, Adly Yacoub, Margaret A. Park, Clint Mitchell, Teneille Walker
Supplementary Data from 17-Allylamino-17-Demethoxygeldanamycin and MEK1/2 Inhibitors Kill GI Tumor Cells via Ca2+-Dependent Suppression of GRP78/BiP and Induction of Ceramide and Reactive Oxygen Species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339bda2c37c9ffeb804512ea476f32c1
https://doi.org/10.1158/1535-7163.22486049
https://doi.org/10.1158/1535-7163.22486049
Autor:
Paul Dent, Paul B. Fisher, Steven Grant, Christina Voelkel-Johnson, David T. Curiel, Sarah Spiegel, Costas Koumenis, Adly Yacoub, Martin Graf, Mohammed Rahmani, Devanand Sarkar, Luni Emdad, Nicollaq Vozhilla, Jeremy Allegood, Aditi Pandya Martin, Teneille Walker, Margaret A. Park
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) is a novel cytokine displaying selective apoptosis-inducing activity in transformed cells without harming normal cells. The present studies focused on clarifying the mechanism(s)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0839fc5d0a27b43570c7a53f7f8ba0c1
https://doi.org/10.1158/1535-7163.c.6531534
https://doi.org/10.1158/1535-7163.c.6531534
Autor:
Paul Dent, Steven Grant, Paul B. Fisher, Christina Voelkel-Johnson, Roland Reinehr, Dieter Häussinger, Mohamed Rahmani, Adly Yacoub, Margaret A. Park, Clint Mitchell, Teneille Walker
The present studies determine in greater detail the molecular mechanisms upstream of the CD95 death receptor by which geldanamycin heat shock protein 90 inhibitors and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e00dc06b0245a0530c2cf53e3f9c9e
https://doi.org/10.1158/1535-7163.c.6532214
https://doi.org/10.1158/1535-7163.c.6532214
Autor:
Paul Dent, Paul B. Fisher, Steven Grant, Christina Voelkel-Johnson, David T. Curiel, Sarah Spiegel, Costas Koumenis, Adly Yacoub, Martin Graf, Mohammed Rahmani, Devanand Sarkar, Luni Emdad, Nicollaq Vozhilla, Jeremy Allegood, Aditi Pandya Martin, Teneille Walker, Margaret A. Park
Supplementary Fig. from MDA-7/IL-24–induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK–dependent mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe590ad39381563a19f0b136e640ac1
https://doi.org/10.1158/1535-7163.22484691
https://doi.org/10.1158/1535-7163.22484691
Publikováno v:
Reprod Toxicol
Dibutyl phthalate (DBP) is a phthalate ester used as a plasticizer, and solvent. Studies using rats consistently report that DBP exposure disrupts normal development of the male reproductive system in part via inhibition of androgen synthesis. Howeve
Autor:
Rebecca L. Morgan, Juleen Lam, Glinda S. Cooper, Andrew D. Kraft, Jennifer M. Ratcliffe, Kristina A. Thayer, Andrew A. Rooney, Holger J. Schünemann, Gloria D. Jahnke, Abee L. Boyles, Teneille Walker, Pamela J. Schwingl, Ruth M. Lunn
Publikováno v:
Environment International, Vol 92, Iss, Pp 617-629 (2016)
Environmental health hazard assessments are routinely relied upon for public health decision-making. The evidence base used in these assessments is typically developed from a collection of diverse sources of information of varying quality. It is crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5adf0ddc5e39c0911f372263cb8fbb3
https://europepmc.org/articles/PMC4902751/
https://europepmc.org/articles/PMC4902751/
Autor:
Michael P. Hagan, Paul B. Fisher, Clint Mitchell, Adly Yacoub, Mohammed Rahmani, Anna Miller, Margaret A. Park, Teneille Walker, Paul Dent, Aditi Pandya Martin, Steven Grant, Luni Emad
Publikováno v:
Molecular Pharmacology. 74:807-822
We have defined some of the mechanisms by which the kinase inhibitor lapatinib kills HCT116 cells. Lapatinib inhibited radiation-induced activation of ERBB1/2, extracellular signal-regulated kinases 1/2, and AKT, and radiosensitized HCT116 cells. Pro
Publikováno v:
Clinical Cancer Research. 12:2232-2238
Purpose: Erythropoietin (EPO) therapy is widely used for the prevention and treatment of anemia resulting from cancer chemotherapy. Native EPO regulates erythropoiesis, at least in part, by protecting erythroid progenitor cells from apoptotic cell de
Autor:
Roland Reinehr, Andrew Thorburn, Dieter Häussinger, Clint Mitchell, Mohamed Rahmani, Margaret A. Park, Aditi Pandya Martin, Steven Grant, Paul Dent, Teneille Walker
Publikováno v:
Molecular pharmacology. 76(2)
We examined whether the multikinase inhibitor sorafenib and histone deacetylase inhibitors (HDACI) interact to kill pancreatic carcinoma cells and determined the impact of inhibiting BCL-2 family function on sorafenib and HDACI lethality. The lethali