Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Teneema Kuriakose"'
Autor:
Teneema Kuriakose
Publikováno v:
Journal of Veterinary and Animal Sciences, Vol 48, Iss 2, Pp 1-5 (2017)
Annual influenza epidemic cause subatantial morbidity, mortality and socio economic tolls. According to WHO estimtes , about three ti five million infections and 250000-500000 deaths occur annually. Influenza pandemic , aglobal outbreak caused by a n
Externí odkaz:
https://doaj.org/article/d7bac303b7a240f8bb32d1e29f3b430c
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005038 (2015)
Mitogen-activated protein kinase (MAP) cascades are important in antiviral immunity through their regulation of interferon (IFN) production as well as virus replication. Although the serine-threonine MAP kinase tumor progression locus 2 (Tpl2/MAP3K8)
Externí odkaz:
https://doaj.org/article/7f5c9a3c36224051a406cd22fce64eb1
Autor:
Jia Xie, Teneema Kuriakose, Brandon Bianski, Nathaniel Twarog, Evan Savage, Ke Xu, Xiaoyan Zhu, Chen He, Baranda Hansen, Hong Wang, Anthony High, Yuxin Li, Jerold E Rehg, Heather S Tillman, Burgess B Freeman, Zoran Rankovic, Arzu Onar-Thomas, Yiping Fan, Gang Wu, Junmin Peng, Shondra Miller, Suzanne J Baker, Anang A Shelat, Christopher L Tinkle
Publikováno v:
Neuro-Oncology.
Background Pediatric high-grade glioma (pHGG) is largely incurable and accounts for most brain tumor-related deaths in children. Radiation is a standard therapy, yet the benefit from this treatment modality is transient, and most children succumb to
Publikováno v:
Circulation. 138:2662-2665
Publikováno v:
Trends in Immunology. 39:123-134
Z-DNA-binding protein 1 (ZBP1), initially reported as an interferon (IFN)-inducible tumor-associated protein, harbors nucleic acid-binding domains for left-handed helix (Z-form) and receptor-interacting protein homotypic interaction motif (RHIM) doma
Autor:
Sannula Kesavardhana, Ashutosh Mishra, Thirumala-Devi Kanneganti, Teneema Kuriakose, Clifford S. Guy, Parimal Samir, R. K. Subbarao Malireddi
Publikováno v:
The Journal of Experimental Medicine
The activation mechanism of ZBP1/DAI to regulate virus-induced programmed cell death is not known. Kesavardhana et al. show that ZBP1 senses viral ribonucleoproteins to induce cell death upon influenza A virus infection. Apical activation of RIG-I–
Publikováno v:
Curr Top Microbiol Immunol
Pyroptosis is a form of lytic, programmed cell death that functions as an innate immune effector mechanism to facilitate host defense against pathogenic microorganisms, including viruses. This type of proinflammatory cell death is orchestrated by pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87063e156ed8985753eca31dfc96f5de
https://europepmc.org/articles/PMC7314647/
https://europepmc.org/articles/PMC7314647/
Publikováno v:
Cell Host & Microbe. 22:7-9
Interferon effector functions and autophagy are evolutionarily conserved arms of cell-autonomous immunity that restrict replication of intracellular pathogens. In this issue of Cell Host and Microbe, Biering et al., (2017) demonstrate how host cells
Publikováno v:
Immunity. 48(1)
The Interleukin-1 (IL-1) family cytokines are cytosolic proteins that exhibit inflammatory activity upon release into the extracellular space. These factors are released following various cell death processes, with pyroptosis being a common mechanism
Publikováno v:
The Journal of Experimental Medicine
ResearcherID
ResearcherID
IFN-I signaling and inflammasome activation are two innate pathways important for combatting a variety of pathogens. Swanson et al. show that cGAMP activates the inflammasome in addition to IFN-I, and that the activation of both is needed to control