Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Teneale A Stewart"'
Autor:
Pieter A Roelofs, Chai Yeen Goh, Boon Haow Chua, Matthew C Jarvis, Teneale A Stewart, Jennifer L McCann, Rebecca M McDougle, Michael A Carpenter, John WM Martens, Paul N Span, Dennis Kappei, Reuben S Harris
Publikováno v:
eLife, Vol 9 (2020)
APOBEC3B (A3B)-catalyzed DNA cytosine deamination contributes to the overall mutational landscape in breast cancer. Molecular mechanisms responsible for A3B upregulation in cancer are poorly understood. Here we show that a single E2F cis-element medi
Externí odkaz:
https://doaj.org/article/562661be3bbb4115a4d955575847fc12
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213751 (2019)
Voltage-gated sodium channels (NaVs) are key therapeutic targets for pain, epilepsy and cardiac arrhythmias. Here we describe the development of a no-wash fluorescent sodium influx assay suitable for high-throughput screening and characterization of
Externí odkaz:
https://doaj.org/article/6ddbba487796479f89231caf45349caa
Autor:
Teneale A. Stewart, Felicity M. Davis
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Mechanical forces play important roles in shaping mammalian development. In the embryo, cells experience force both during the formation of the mammalian body plan and in the ensuing phase of organogenesis. Physical forces – including fluid flow, c
Externí odkaz:
https://doaj.org/article/525efd986aaf4cbe817f7ef32ad355ef
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Mammary gland development begins in the embryo and continues throughout the reproductive life of female mammals. Tissue macrophages (Mϕs), dependent on signals from the Mϕ colony stimulating factor 1 receptor (CSF1R), have been shown to regulate th
Externí odkaz:
https://doaj.org/article/87379b517ea847749aaceb1eaad8a330
Autor:
Jason S. Lee, Frank Gannon, Nicola Waddell, Paula M. Vertino, Nicholas K. Hayward, Felicity M. Davis, Dorim Kim, Mariska Miranda, Stephen H. Kazakoff, Pamela Mukhopadhyay, Teneale A. Stewart, Nabilah Kamal, Priya Ramarao-Milne, Gregory M. Kelly, Francesco Casciello
G9a and EZH2 are two histone methyltransferases commonly upregulated in several cancer types, yet the precise roles that these enzymes play cooperatively in cancer is unclear. We demonstrate here that frequent concurrent upregulation of both G9a and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76ef525d0abe326283a0446da9b7dcb0
https://doi.org/10.1158/0008-5472.c.6513936.v1
https://doi.org/10.1158/0008-5472.c.6513936.v1
Autor:
Jason S. Lee, Frank Gannon, Nicola Waddell, Paula M. Vertino, Nicholas K. Hayward, Felicity M. Davis, Dorim Kim, Mariska Miranda, Stephen H. Kazakoff, Pamela Mukhopadhyay, Teneale A. Stewart, Nabilah Kamal, Priya Ramarao-Milne, Gregory M. Kelly, Francesco Casciello
Supplementary Data from Combined Inhibition of G9a and EZH2 Suppresses Tumor Growth via Synergistic Induction of IL24-Mediated Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b04b592fecd2dd060667581d926e43
https://doi.org/10.1158/0008-5472.22431540.v1
https://doi.org/10.1158/0008-5472.22431540.v1
Autor:
Francesco Casciello, Gregory M. Kelly, Priya Ramarao-Milne, Nabilah Kamal, Teneale A. Stewart, Pamela Mukhopadhyay, Stephen H. Kazakoff, Mariska Miranda, Dorim Kim, Felicity M. Davis, Nicholas K. Hayward, Paula M. Vertino, Nicola Waddell, Frank Gannon, Jason S. Lee
Publikováno v:
Cancer Research. 82:1208-1221
G9a and EZH2 are two histone methyltransferases commonly upregulated in several cancer types, yet the precise roles that these enzymes play cooperatively in cancer is unclear. We demonstrate here that frequent concurrent upregulation of both G9a and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3434303eda1b08a06c33e42ff992ec37
https://doi.org/10.1158/0008-5472.can-21-2218
https://doi.org/10.1158/0008-5472.can-21-2218
Autor:
Sarah J. Roberts-Thomson, Amelia A. Peters, Gregory R. Monteith, Erik W. Thompson, Daneth L. Marcial, Iman Azimi, Silke B. Chalmers, Teneale A. Stewart, Kunsala T. D. S. Yapa
Publikováno v:
Laboratory Investigation. 100:224-233
The Ca2+ signal is essential in both hypoxia- and epidermal growth factor (EGF)-mediated epithelial to mesenchymal transition (EMT) in MDA-MB-468 breast cancer cells. This finding suggests that Ca2+-permeable ion channels participate in the induction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d3a71187b77bb88a5e6dc4aec7b3b5
https://doi.org/10.1038/s41374-019-0280-3
https://doi.org/10.1038/s41374-019-0280-3
Autor:
Sunil R. Lakhani, Jodi M. Saunus, Priyakshi Kalita-de Croft, Mélanie Robitaille, Sarah J. Roberts-Thomson, Patsy S. Soon, Gregory R. Monteith, Teneale A. Stewart, Francisco Sadras, Amelia A. Peters
Publikováno v:
Biomedicines
Volume 9
Issue 6
Biomedicines, Vol 9, Iss 680, p 680 (2021)
Volume 9
Issue 6
Biomedicines, Vol 9, Iss 680, p 680 (2021)
Cancer-associated fibroblasts (CAFs) represent an important component of the tumour microenvironment and are implicated in disease progression. Two outstanding questions in cancer biology are how CAFs arise and how they might be targeted therapeutica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e674118920d1425a9de8edd088c099b
http://europepmc.org/articles/PMC8234491
http://europepmc.org/articles/PMC8234491
Autor:
Felicity M. Davis, Teneale A. Stewart
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:1230-1238
Life begins with calcium. It is the language that a sperm cell uses to respond to instructions from the female reproductive tract to alter its swimming pattern and gain the force required to penetrate the outer layers of the oocyte. The first heartbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e879430bf9f86c2c30a62ca95a1ade
https://doi.org/10.1016/j.bbamcr.2019.02.016
https://doi.org/10.1016/j.bbamcr.2019.02.016