Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Tendon formation"'
Autor:
Dan Luo, Yu Wang, Yan Liu, Lisha Zhu, Bo Guan, Cun-Yu Wang, Danqing He, Shanshan Jin, Ting Zhang, Yanheng Zhou, Chunyan Shi, Zixin Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
Tendon injuries disrupt the balance between stability and mobility, causing compromised functions and disabilities. The regeneration of mature, functional tendons remains a clinical challenge. Here, we perform transcriptional profiling of tendon deve
Publikováno v:
Acta Biomedica Scientifica, Vol 5, Iss 6, Pp 66-76 (2021)
Acta Biomedica Scientifica, Vol 6, Iss 2, Pp 166-175 (2021)
Acta Biomedica Scientifica, Vol 6, Iss 2, Pp 166-175 (2021)
Injuries and degenerative changes of tendons are common damages of the musculoskeletal system. Due to its hypovascular character the tendon has a limited natural ability to recover. For typical surgical treatment, the tendon integrity is restored, bu
Autor:
Naoya Kozono, Yoshitaka Nakanishi, Yasuharu Nakashima, Takahiro Senju, Koichi Nakayama, Naohide Takeuchi, Takamitsu Okada
Publikováno v:
Regenerative Therapy, Vol 11, Iss, Pp 47-55 (2019)
Regenerative Therapy
Regenerative Therapy
Introduction Tendon tissue engineering requires scaffold-free techniques for safe and long-term clinical applications and to explore alternative cell sources to tenocytes. Therefore, we histologically assessed tendon formation in a scaffold-free Bio-
Autor:
Pernilla Eliasson, Franciele Dietrich-Zagonel, Andreas Herchenhan, Peter Schjerling, Michael Kjaer
Publikováno v:
Journal of Orthopaedic Research. 38:173-181
Tendon cells exist in a dense extracellular matrix and mechanical loading is important for the strength development of this matrix. We therefore use a three-dimensional (3D) culture system for tendon formation in vitro. The objectives of this study w
Publikováno v:
J Orthop Res
Extracellular matrix (ECM) determines the physiological function of all tissues, including musculoskeletal tissues. In tendon, ECM provides overall tissue architecture, which is tailored to match the biomechanical requirements of their physiological
Autor:
Abigail R. Raveling, Alleyna C Martes, Nicholas M. Pancheri, Jeffrey M. Courtright, Michele R. Brumley, Nathan R. Schiele, Sophia K. Theodossiou, Aimee L. Bozeman
Publikováno v:
J Biomech Eng
Mechanical loading may be required for proper tendon formation. However, it is not well understood how tendon formation is impacted by the development of weight-bearing locomotor activity in the neonate. This study assessed tendon mechanical properti
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620175
Bioreactors can offer an advanced platform to provide conditions that mimic the native microenvironment, which can also provide stretching environment for mechanobiology research. Tendon-derived stem cells (TDSCs) are a type of mechanosensitive and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99997ab91b8ca6eadfcf616d6b2b9ca6
https://doi.org/10.1007/7651_2021_432
https://doi.org/10.1007/7651_2021_432
Publikováno v:
BMC musculoskeletal disorders, vol 21, iss 1
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders, Vol 21, Iss 1, Pp 1-11 (2020)
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders, Vol 21, Iss 1, Pp 1-11 (2020)
Background Tendon injuries amount to one of the leading causes of career-ending injuries in horses due to the inability for tendon to completely repair and the high reinjury potential. As a result, novel therapeutics are necessary to improve repair w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278903d8809431671acad6e3883738da
https://escholarship.org/uc/item/6fp5r1nt
https://escholarship.org/uc/item/6fp5r1nt
Autor:
Stephanie N. Weiss, Nathaniel A. Dyment, Louis J. Soslowsky, Snehal S. Shetye, Ryan J. Leiphart
Publikováno v:
J Biomech Eng
Tendon injuries increase with age, yet the age-associated changes in tendon properties remain unexplained. Decorin and biglycan are two matrix proteoglycans that play complex roles in regulating tendon formation, maturation, and aging, most notably i
Publikováno v:
Connective Tissue Research. 59:495-508
Tendon is a specialized connective tissue that connects muscle to bone, thereby enabling musculoskeletal movement. Tendon injury leads to formation of tissue with aberrant functional properties. Current approaches to treat tendon injuries, including