Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tena G. Goodwin"'
Article Commentary: First Human Myoblast Transfer Therapy Continues to Show Dystrophin after 6 Years
Autor:
Peter K. Law Ph.D., Tena G. Goodwin, Qiuwen Fang, Terry L. Hall, Tom Quinley, George Vastagh, Vijaya Duggirala, Charles Larkin, Jerry Ann Florendo, Lawrence Li, Tunja Jackson, T. J. Yoo, Nancy Chase, Michael Neel, Tim Krahn, Randall Holcomb
Publikováno v:
Cell Transplantation, Vol 6 (1997)
Externí odkaz:
https://doaj.org/article/e2223f2a77d74952886020e65dfa916d
Autor:
Peter K. Law, Tena G. Goodwin, Qiuwen Fang, Mary Beth Deering, Vijaya Duggirala, Charles Larkin, J. Ann Florendo, Dana S. Kirby, H.J. Li, Ming Chen, Jennifer Cornett, Lawrence M. Li, Afshin Shirzad, Thomas Quinley, T.J. Yoo, Randall Holcomb
Publikováno v:
Cell Transplantation, Vol 2 (1993)
The feasibility, safety, and efficacy of myoblast transfer therapy (MTT) were assessed in an experimental lower body treatment (LBT) involving 32 Duchenne muscular dystrophy (DMD) boys aged 6-14 yr, half of whom were nonambulatory. Through 48 injecti
Externí odkaz:
https://doaj.org/article/13b265b44e9a4dfb8771fdd6949a5781
Autor:
Peter K. Law, Tena G. Goodwin, Qiuwen Fang, Vijaya Duggirala, Charles Larkin, J. Ann Florendo, Dana S. Kirby, Mary Beth Deering, H.J. Li, Ming Chen, T.J. Yoo, Jennifer Cornett, Lawrence M. Li, Afshin Shirzad, Thomas Quinley, Randall L. Holcomb
Publikováno v:
Cell Transplantation, Vol 1 (1992)
Five billion normal myoblasts were injected into each of 21 Duchenne muscular dystrophy (DMD) boys aged 6–14 yr to assess the feasibility, safety, and efficacy of the Phase II myoblast transfer therapy (MTT). The Phase II study was designed to stre
Externí odkaz:
https://doaj.org/article/4eb6f5ee12fc45f4b9a128dee472a4eb
Publikováno v:
Cell Transplantation, Vol 1 (1992)
A new technique enables correlation of dystrophin expression with the location of donor versus host nuclei in the same sections of mdx mouse muscle injected with normal myoblasts. Myoblasts from C57BL/6J mice or from humans were labeled with 0.01% fl
Externí odkaz:
https://doaj.org/article/577d510c040742459db7a89f8b6debf0
Autor:
L.M. Li, T. Quinley, M. Neel, Tena G. Goodwin, Peter K. Law, T. Jackson, Q. Fang, T. Hall, C. Larkin, T. Krahn, Duggirala, G. Vastagh, R. Holcomb, T.J. Yoo, N. Chase, J.A. Florendo
Publikováno v:
Cell Transplantation. 6:95-100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5c0d2586bfcb94ccbc08e6a4f6e5c74
https://doi.org/10.1016/s0963-6897(96)00138-8
https://doi.org/10.1016/s0963-6897(96)00138-8
Autor:
Q. Fang, Ming Chen, Peter K. Law, B.S. Kirby, Tena G. Goodwin, Hua-ju Li, S Dana, J. Ann Florendo
Publikováno v:
Acta paediatrica Japonica : Overseas edition. 33(2)
A randomly selected extensor digitorum brevis (EDB) muscle in each of three Duchenne muscular dystrophy (DMD) boys aged 9 to 10 was injected with approximately 8 x 10(6) myoblasts. The contralateral EDBs were sham-injected with carrier solution. Dono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c94e0768aa167973d6533a6d3abc5ff
https://pubmed.ncbi.nlm.nih.gov/1957647
https://pubmed.ncbi.nlm.nih.gov/1957647
Publikováno v:
Canadian journal of physiology and pharmacology. 69(1)
A new method is developed using Fluoro-Gold (FG) as a vital stain to label the nuclei of donor myoblasts in myoblast transfer studies. In vitro incubation with 0.01% FG for 16 h resulted in 100% nuclei labelling. Intensive fluorescence persisted foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a593aed44dc79794630b46c96bce3416
https://pubmed.ncbi.nlm.nih.gov/2036600
https://pubmed.ncbi.nlm.nih.gov/2036600
Publikováno v:
Myoblast Transfer Therapy ISBN: 9781468458671
Dystrophic cells degenerate because they lack the normal genome. In our laboratory, transplant techniques have been developed to facilitate cell survival and cell fusion, such that the normal genome can be incorporated back into the dystrophic muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e8016b96e58e425c88bb3bd8f8544bb
https://doi.org/10.1007/978-1-4684-5865-7_10
https://doi.org/10.1007/978-1-4684-5865-7_10
Publikováno v:
Myoblast Transfer Therapy ISBN: 9781468458671
As of April 7, the Institutional Review Board has approved our proposal on human trial with myoblast transfer therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be177ff30a191dc6c34de619eefa262c
https://doi.org/10.1007/978-1-4684-5865-7_28
https://doi.org/10.1007/978-1-4684-5865-7_28
Autor:
Ming Chen, Henry G. Herrod, Hua Ju Li, Dana S. Kirby, Peter K. Law, Gerald S. Golden, Q. Fang, J. Ann Florendo, Tena G. Goodwin, Tulio E. Bertorini
Publikováno v:
The Lancet. 336:114-115
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8409e19e5ad84861281ac7ca8126846c
https://doi.org/10.1016/0140-6736(90)91628-n
https://doi.org/10.1016/0140-6736(90)91628-n