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pro vyhledávání: '"Ten-Yuan Chang"'
Autor:
Ya-Feng Shih, Po-Huang Liang, Yu-Sheng Chao, Shin-Ru Shih, Ten-Yuan Chang, Jiun-Jie Shie, Jim-Min Fang, Jin-Ching Lee, Wei-Chun Chen, Kuei-Jung Yen, Huan-Yi Tseng, John T.A. Hsu
Publikováno v:
Analytical Biochemistry. 375:115-123
Although several cell-based reporter assays have been developed for screening of viral protease inhibitors, most of these assays have a significant limitation in that numerous false positives can be generated for the compounds that are interfering wi
Publikováno v:
Analytical Biochemistry. 316:162-170
The hepatitis C virus (HCV) contains a positive-sense RNA genome that encodes a unique polyprotein precursor, which must be processed by proteases to enable viral maturation. Virally encoded NS3/4A protease has thus become an attractive target for th