The aconitate decarboxylase 1/itaconate pathway modulates immune dysregulation and associates with cardiovascular disease markers in SLE.

Autor: Patiño-Martinez E; Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA., Nakabo S; Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA., Jiang K; Biodata Mining and Discovery Section, NIAMS/NIH., Carmona-Rivera C; Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA., Tsai WL; Translational Immunology Section, NIAMS/NIH., Claybaugh D; Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA., Yu ZX; National Heart, Lung, and Blood Institute (NHLBI), NIH., Romero A; Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA., Bohrnsen E; Protein & Chemistry Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Hamilton, MT, USA., Schwarz B; Protein & Chemistry Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Hamilton, MT, USA., Solís-Barbosa MA; Department of Molecular Biomedicine, Centro de Investigación y de Estudios Avanzados del I.P.N, 07360 Mexico City, Mexico., Blanco LP; Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA., Naqi M; Lupus Clinical Trials Unit, NIAMS/NIH., Temesgen-Oyelakim Y; Lupus Clinical Trials Unit, NIAMS/NIH., Davis M; Lupus Clinical Trials Unit, NIAMS/NIH., Manna Z; Lupus Clinical Trials Unit, NIAMS/NIH., Mehta N; National Heart, Lung, and Blood Institute (NHLBI), NIH., Naz F; Office of Science and Technology, NIAMS/NIH., Brooks S; Office of Science and Technology, NIAMS/NIH., dell'Orso S; Office of Science and Technology, NIAMS/NIH., Hasni S; Lupus Clinical Trials Unit, NIAMS/NIH., Kaplan MJ; Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Feb 22. Date of Electronic Publication: 2024 Feb 22.