DNA damage Evaluation in a Nursing Team Occupationally Exposed to Ionizing Radiation

Autor: Iranez Bortolotto, Ana Paula S. Brum, Larissa M. de Souza, Cristiano Trindade, Temenouga N. Guecheva, Fabiano M Luiz, Ana Ligia L de Paula-Ramos, Angelica R. Consiglio

Publikováno v: Brazilian Journal of Radiation Sciences, Vol 3, Iss 1 (2015)

Purpose: To evaluate DNA damage in lymphocytes and cognitive deficits in a nursing team occupationally exposed to ionizing radiation in a university hospital in southern Brazil. Method: Cross-sectional study, case-control design, included 79 women wo

Externí odkaz: https://doaj.org/article/ade6fdbdb93b43d1801e94213288aa0c

Diphenyl Ditelluride: Redox-Modulating and Antiproliferative Properties

Autor: João Antonio Pêgas Henriques, Priscila dos Santos Silveira, José Eduardo Vargas, Renato David Puga, Iuri Marques de Oliveira, Temenouga N. Guecheva, Cristiano Trindade, André Luiz Mendes Juchem, Cláudia Pessoa

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Volume 2019
Repositorio Digital USB
Universidad Simón Bolívar
instacron:Universidad Simón Bolívar

Tellurium is a rare element that has been regarded as a toxic, nonessential element, and its biological role is not clearly established. In addition, the biological effects of elemental tellurium and some of its organic and inorganic derivatives have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3b8d4e3708ddf98c7c372cfc4f7ba4
https://doi.org/10.1155/2019/2510936

Saccharomyces cerevisiae DNA repair pathways involved in repair of lesions induced by mixed ternary mononuclear Cu(II) complexes based on valproic acid with 1,10-phenanthroline or 2,2’- bipyridine ligands

Autor: João Antonio Pêgas Henriques, Gabriel Berbigier Rodrigues, Miriana da Silva Machado, Sidnei Moura, Claus Tröger Pich, Priscila dos Santos Silveira, Temenouga N. Guecheva, Iuri Marques de Oliveira, Mariana Roesch-Ely, Françoise Dumas

Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :503390

The sodium valproate has been largely used as an anti-epilepsy drug and, recently, as a putative drug in cancer therapy. However, the treatment with sodium valproate has some adverse effects. In this sense, more effective and secure complexes than so

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670551e151298dfeda91fd8e27a977d9
https://doi.org/10.1016/j.mrgentox.2021.503390

Role of nucleotide excision repair proteins in response to DNA damage induced by topoisomerase II inhibitors

Autor: Jaqueline Cesar Rocha, Franciele Faccio Busatto, Temenouga N. Guecheva, Jenifer Saffi

Publikováno v: Mutation Research/Reviews in Mutation Research. 768:68-77

In cancer treatment, chemotherapy is one of the main strategies used. The knowledge of the cellular and molecular characteristics of tumors allows the use of more specific drugs, making the removal of tumors more efficient. Among the drugs of choice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adb575ca6c92d033de6a231945ce5f7
https://doi.org/10.1016/j.mrrev.2016.04.004

Antigenotoxic and antimutagenic effects of diphenyl ditelluride against several known mutagens in Chinese hamster lung fibroblasts

Autor: Nathalia Rammé Medeiros de Albuquerque, João Antonio Pêgas Henriques, Iuri Marques de Oliveira, André Luiz Mendes Juchem, Temenouga N. Guecheva, Renato Moreira Rosa, Cristiano Trindade, Jenifer Saffi

Publikováno v: Mutagenesis. 30:799-809

The present study evaluates antigenotoxic and antimutagenic properties of diphenyl ditelluride (DPDT) against several known mutagens in Chinese hamster lung fibroblasts (V79 cells). DPDT was not cytotoxic and genotoxic at concentrations ranging from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8e3f047320f0c64221e0b4e7818082
https://doi.org/10.1093/mutage/gev037