Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines

Autor: Temburnikar, Kartik W., Zimmermann, Sarah C., Kim, Nathaniel T., Ross, Christina R., Gelbmann, Christopher, Salomon, Christine E., Wilson, Gerald M., Balzarini, Jan, Seley-Radtke, Katherine L.

Publikováno v: In Bioorganic & Medicinal Chemistry 1 April 2014 22(7):2113-2122

Evaluating TNA stability under simulated physiological conditions

Autor: Culbertson, Michelle C, Temburnikar, Kartik W, Sau, Sujay P, Liao, Jen-Yu, Bala, Saikat, Chaput, John C

Publikováno v: Culbertson, MC; Temburnikar, KW; Sau, SP; Liao, J-Y; Bala, S; & Chaput, JC. (2016). Evaluating TNA stability under simulated physiological conditions. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 26(10), 2418-2421. doi: 10.1016/j.bmcl.2016.03.118. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2wg133f5
Bioorganic & medicinal chemistry letters, vol 26, iss 10

Chemically modified oligonucleotides are routinely used as diagnostic and therapeutic agents due to their enhanced biological stability relative to natural DNA and RNA. Here, we examine the biological stability of α-l-threofuranosyl nucleic acid (TN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6d26499e827f922dfa1a6936b690e412
http://www.escholarship.org/uc/item/2wg133f5

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