Endoplasmic reticulum stress in pancreatic β-cell dysfunction: The potential therapeutic role of dietary flavonoids.

Autor: Mbara KC; Nanomedicines Manufacturing, Biopharmaceutics and Diagnostics Research Laboratory, Department of Pharmaceutical Sciences, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa., Fotsing MCD; Drug Discovery and Smart Molecules Research Laboratory, Centre for Natural Products Research (CNPR), Department of Chemical Sciences, University of Johannesburg, Doornfontein, Johannesburg, 2028, South Africa., Ndinteh DT; Drug Discovery and Smart Molecules Research Laboratory, Centre for Natural Products Research (CNPR), Department of Chemical Sciences, University of Johannesburg, Doornfontein, Johannesburg, 2028, South Africa., Mbeb CN; Nanomedicines Manufacturing, Biopharmaceutics and Diagnostics Research Laboratory, Department of Pharmaceutical Sciences, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa., Nwagwu CS; Drug Delivery and Nanomedicines Research Laboratory, Department of Pharmaceutics, University of Nigeria, Nsukka, Enugu State, Nigeria., Khan R; Discipline of Medical Biochemistry, School of Laboratory Medicine and Medical Science, University of KwaZulu-Natal, Durban, South Africa., Mokhetho KC; Nanomedicines Manufacturing, Biopharmaceutics and Diagnostics Research Laboratory, Department of Pharmaceutical Sciences, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa., Baijnath H; Ward Herbarium, School of Life Sciences, University of KwaZulu-Natal, Durban, 4000, KwaZulu-Natal, South Africa., Nlooto M; Department of Pharmaceutical Sciences, Healthcare Sciences, University of Limpopo, South Africa., Mokhele S; Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, 0208, South Africa., Leonard CM; Nanomedicines Manufacturing, Biopharmaceutics and Diagnostics Research Laboratory, Department of Pharmaceutical Sciences, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa., Tembu VJ; Natural Products Chemistry Research Laboratory, Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa., Tarirai C; Nanomedicines Manufacturing, Biopharmaceutics and Diagnostics Research Laboratory, Department of Pharmaceutical Sciences, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa.

Publikováno v: Current research in pharmacology and drug discovery [Curr Res Pharmacol Drug Discov] 2024 May 24; Vol. 6, pp. 100184. Date of Electronic Publication: 2024 May 24 (Print Publication: 2024).

Phytochemicals from Pterocarpus angolensis DC and Their Cytotoxic Activities against Breast Cancer Cells.

Autor: Teclegeorgish ZW; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0083, South Africa., Mokgalaka NS; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0083, South Africa., Kemboi D; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0083, South Africa.; Department of Chemistry, University of Kabianga, Kericho 2030-20200, Kenya., Krause RWM; Department of Chemistry, Rhodes University, Makhanda 6140, South Africa., Siwe-Noundou X; Department of Pharmaceutical Science, Sefako Makgatho Health Science University, P.O. Box 60, Medunsa, Pretoria 0204, South Africa., Nyemba GR; Department of Biochemistry and Microbiology, Female Cancers Research at Rhodes University (FemCR2U), Makhanda 6140, South Africa., Davison C; Department of Biochemistry and Microbiology, Female Cancers Research at Rhodes University (FemCR2U), Makhanda 6140, South Africa., de la Mare JA; Department of Biochemistry and Microbiology, Female Cancers Research at Rhodes University (FemCR2U), Makhanda 6140, South Africa., Tembu VJ; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0083, South Africa.

Publikováno v: Plants (Basel, Switzerland) [Plants (Basel)] 2024 Jan 19; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 19.

Ethnomedicinal Uses, Phytochemistry and Pharmacological Properties of Suregada Genus: A Review.

Autor: Mangisa M; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa., Kemboi D; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa.; Department of Chemistry, University of Kabianga, Kericho 2030, Kenya., Fouche G; Department of Chemistry, University of Pretoria, Private Bag X20, Pretoria 0001, South Africa., Nthambeleni R; Biosciences, Council for Scientific and Industrial Research, Pretoria 0001, South Africa., Langat MK; Science Department, Royal Botanic Gardens, Kew TW9 3DS, UK., Tarirai C; Department of Pharmaceutical Sciences, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa., Cheek M; Science Department, Royal Botanic Gardens, Kew TW9 3DS, UK., Gonyela O; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa., Tembu VJ; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria 0001, South Africa.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Sep 30; Vol. 16 (10). Date of Electronic Publication: 2023 Sep 30.

In vitro cytotoxic effect of stigmasterol derivatives against breast cancer cells.

Autor: Dube NP; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa., Tembu VJ; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa., Nyemba GR; Department of Biochemistry and Microbiology, Female Cancers Research at Rhodes University (FemCR2U), Makhanda/Grahamstown, 6140, South Africa., Davison C; Department of Biochemistry and Microbiology, Female Cancers Research at Rhodes University (FemCR2U), Makhanda/Grahamstown, 6140, South Africa., Rakodi GH; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa., Kemboi D; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa.; Department of Physical Sciences, University of Kabianga, Kericho, 2030, Kenya., de la Mare JA; Department of Biochemistry and Microbiology, Female Cancers Research at Rhodes University (FemCR2U), Makhanda/Grahamstown, 6140, South Africa., Siwe-Noundou X; Department of Pharmaceutical Sciences, Sefako Makgatho Health Sciences University, Pretoria, 0204, South Africa., Manicum AE; Department of Chemistry, Tshwane University of Technology, Private Bag X680, Pretoria, 0001, South Africa. dubendumi@gmail.com.

Publikováno v: BMC complementary medicine and therapies [BMC Complement Med Ther] 2023 Sep 11; Vol. 23 (1), pp. 316. Date of Electronic Publication: 2023 Sep 11.

Exploring the in vitro anticancer activities of Re(I) picolinic acid and its fluorinated complex derivatives on lung cancer cells: a structural study.

Autor: Matlou ML; Department of Chemistry, Tshwane University of Technology, P.O. Box X680, Pretoria, 0001, South Africa., Malan FP; Department of Chemistry, University of Pretoria, 02 Lynnwood Road, Hatfield, Pretoria, 0001, South Africa., Nkadimeng S; Department of Life and Consumer Sciences, University of South Africa, Private Bag X6, Florida Campus, Florida, 1710, South Africa., McGaw L; Phytomedicine Programme, Department of Paraclinical Sciences, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa., Tembu VJ; Department of Chemistry, Tshwane University of Technology, P.O. Box X680, Pretoria, 0001, South Africa., Manicum AE; Department of Chemistry, Tshwane University of Technology, P.O. Box X680, Pretoria, 0001, South Africa. ManicumAE@tut.ac.za.

Publikováno v: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry [J Biol Inorg Chem] 2023 Feb; Vol. 28 (1), pp. 29-41. Date of Electronic Publication: 2022 Dec 04.