Zobrazeno 1 - 10
of 391
pro vyhledávání: '"Telomeric heterochromatin"'
Publikováno v:
Caryologia, Vol 72, Iss 2 (2019)
Centromeres are generally embedded in heterochromatin, which is assumed to have a negative impact on meiotic recombination in adjacent regions, a condition required for the correct segregation of chromosomes at anaphase I. At difference, telomeric an
Externí odkaz:
https://doaj.org/article/5c9453d9eab444fc8c2ff7dbc0d1c21f
Publikováno v:
Biochemistry (Moscow). 86:1526-1539
The telomere theory tries to explain cellular mechanisms of aging as mainly caused by telomere shortening at each duplication. The subtelomere–telomere theory overcomes various shortcomings of telomere theory by highlighting the essential role of s
Publikováno v:
Chromosoma. 129:201-214
Heterochromatin protein 1a (HP1a) is a well-known component of pericentromeric and telomeric heterochromatin in Drosophila. However, its role and the mechanisms of its binding in the chromosome arms (ChAs) remain largely unclear. Here, we identified
Autor:
Amparo Serna, Corrado Caslini
Telomere transcription into telomeric repeat-containing RNA (TERRA) is an integral component of all aspects of chromosome end protection consisting of telomerase- or recombination-dependent telomere elongation, telomere capping, and preservation of (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::678363f11b4698e405254bed25eece2e
https://doi.org/10.1101/2021.06.18.449032
https://doi.org/10.1101/2021.06.18.449032
Publikováno v:
Life science alliance. 4(11)
Telomeres, highly ordered DNA-protein complexes at eukaryotic linear chromosome ends, are specialized heterochromatin loci conserved among eukaryotes. In Schizosaccharomyces pombe, the shelterin complex is important for subtelomeric heterochromatin e
Autor:
Timothy Hoggard, Catherine A. Fox, Conrad A. Nieduszynski, Michael Weinreich, Carolin A. Müller
Publikováno v:
Proc Natl Acad Sci U S A
A eukaryotic chromosome relies on the function of multiple spatially distributed DNA replication origins for its stable inheritance. The location of an origin is determined by the chromosomal position of an MCM complex, the inactive form of the DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a71fccc451b5232cff6ee04d923302
Publikováno v:
Caryologia, Vol 72, Iss 2 (2019)
Caryologia
Caryologia, Firenze University Press, 2019, 72 (2), pp.63-68. ⟨10.13128/cayologia-194⟩
Caryologia
Caryologia, Firenze University Press, 2019, 72 (2), pp.63-68. ⟨10.13128/cayologia-194⟩
Centromeres are generally embedded in heterochromatin, which is assumed to have a negative impact on meiotic recombination in adjacent regions, a condition required for the correct segregation of chromosomes at anaphase I. At difference, telomeric an
Autor:
Ying Jie Lock, Anqi Dai, Himabindu Gali, Adam Labadorf, Rachel Litman Flynn, Jess Floro, Adeline Matschulat, Matthew Reiss, Emily Mason-Osann
Publikováno v:
Oncotarget
The Alternative Lengthening of Telomeres (ALT) pathway stimulates telomere elongation and prevents cellular senescence in approximately 60% of osteosarcoma. While the precise mechanism underlying activation of the ALT pathway is unclear, mutations in
Autor:
William J. Belden, Emily T. Mirek, Qiaoqiao Zhu, Tracy G. Anthony, Li Na, Hamidah Raduwan, Jinhee Park
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 10, p e0223803 (2019)
PLoS ONE, Vol 14, Iss 10, p e0223803 (2019)
The circadian clock and aging are intertwined. Disruption to the normal diurnal rhythm accelerates aging and corresponds with telomere shortening. Telomere attrition also correlates with increase cellular senescence and incidence of chronic disease.
Autor:
Hong-Liang Bao, Yan Xu
Publikováno v:
Nature Protocols. 13:652-665
Growing evidence indicates that RNA G-quadruplexes have important roles in various processes such as transcription, translation, regulation of telomere length, and formation of telomeric heterochromatin. Investigation of RNA G-quadruplex structures a