Zobrazeno 1 - 10
of 392
pro vyhledávání: '"Telomeric heterochromatin"'
Publikováno v:
Caryologia, Vol 72, Iss 2 (2019)
Centromeres are generally embedded in heterochromatin, which is assumed to have a negative impact on meiotic recombination in adjacent regions, a condition required for the correct segregation of chromosomes at anaphase I. At difference, telomeric an
Externí odkaz:
https://doaj.org/article/5c9453d9eab444fc8c2ff7dbc0d1c21f
Akademický článek
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Publikováno v:
Biochemistry (Moscow). 86:1526-1539
The telomere theory tries to explain cellular mechanisms of aging as mainly caused by telomere shortening at each duplication. The subtelomere–telomere theory overcomes various shortcomings of telomere theory by highlighting the essential role of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778afdd1947c6052ff1da38b5ff9ec49
https://doi.org/10.1134/s0006297921120026
https://doi.org/10.1134/s0006297921120026
Publikováno v:
Chromosoma. 129:201-214
Heterochromatin protein 1a (HP1a) is a well-known component of pericentromeric and telomeric heterochromatin in Drosophila. However, its role and the mechanisms of its binding in the chromosome arms (ChAs) remain largely unclear. Here, we identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7828bf7dd0270eb811f8cd453dfb37b
https://doi.org/10.1007/s00412-020-00738-5
https://doi.org/10.1007/s00412-020-00738-5
Autor:
Amparo Serna, Corrado Caslini
Telomere transcription into telomeric repeat-containing RNA (TERRA) is an integral component of all aspects of chromosome end protection consisting of telomerase- or recombination-dependent telomere elongation, telomere capping, and preservation of (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::678363f11b4698e405254bed25eece2e
https://doi.org/10.1101/2021.06.18.449032
https://doi.org/10.1101/2021.06.18.449032
Publikováno v:
Life science alliance. 4(11)
Telomeres, highly ordered DNA-protein complexes at eukaryotic linear chromosome ends, are specialized heterochromatin loci conserved among eukaryotes. In Schizosaccharomyces pombe, the shelterin complex is important for subtelomeric heterochromatin e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8023c9c722c1f6868c0c3680910262f
https://pubmed.ncbi.nlm.nih.gov/34493579
https://pubmed.ncbi.nlm.nih.gov/34493579
Autor:
Timothy Hoggard, Catherine A. Fox, Conrad A. Nieduszynski, Michael Weinreich, Carolin A. Müller
Publikováno v:
Proc Natl Acad Sci U S A
A eukaryotic chromosome relies on the function of multiple spatially distributed DNA replication origins for its stable inheritance. The location of an origin is determined by the chromosomal position of an MCM complex, the inactive form of the DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a71fccc451b5232cff6ee04d923302
Autor:
Ying Jie Lock, Anqi Dai, Himabindu Gali, Adam Labadorf, Rachel Litman Flynn, Jess Floro, Adeline Matschulat, Matthew Reiss, Emily Mason-Osann
Publikováno v:
Oncotarget
The Alternative Lengthening of Telomeres (ALT) pathway stimulates telomere elongation and prevents cellular senescence in approximately 60% of osteosarcoma. While the precise mechanism underlying activation of the ALT pathway is unclear, mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb6af2a430194cb2d55b8441bffa3f7
https://doi.org/10.18632/oncotarget.26029
https://doi.org/10.18632/oncotarget.26029
Autor:
Hong-Liang Bao, Yan Xu
Publikováno v:
Nature Protocols. 13:652-665
Growing evidence indicates that RNA G-quadruplexes have important roles in various processes such as transcription, translation, regulation of telomere length, and formation of telomeric heterochromatin. Investigation of RNA G-quadruplex structures a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aaccf98500546cdc96d8a6bb2850165
https://doi.org/10.1038/nprot.2017.156
https://doi.org/10.1038/nprot.2017.156
Autor:
Diego Megías, Alvaro Castells-Garcia, Isabel López-Silanes, Maria A. Blasco, Mario F. Fraga, Juan J Montero
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Recercat. Dipósit de la Recerca de Catalunya
instname
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
Digital.CSIC. Repositorio Institucional del CSIC
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Instituto de Salud Carlos III (ISCIII)
Recercat. Dipósit de la Recerca de Catalunya
instname
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
Digital.CSIC. Repositorio Institucional del CSIC
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
TERRAs are long non-coding RNAs generated from the telomeres. Lack of TERRA knockout models has hampered understanding TERRAs' functions. We recently identified chromosome 20q as one of the main origins of human TERRAs, allowing us to generate the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9545028123902ab51e2c48d3e7d576c9
https://hdl.handle.net/20.500.12105/6508
https://hdl.handle.net/20.500.12105/6508