Výsledky vyhledávání - "Telomerase RNA component"

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Telomerase RNA component lncRNA as potential diagnostic biomarker promotes CRC cellular migration and apoptosis evasion via modulation of β-catenin protein level

Autor: Bakr, Mohamed, Abd-Elmawla, Mai A., Elimam, Hanan, Gamal El-Din, Hebatallah, Fawzy, Amal, Abulsoud, Ahmed I., Rizk, Sherine M.

Publikováno v: In Non-coding RNA Research September 2023 8(3):302-314

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Dyskerin and telomerase RNA component are sex-differentially associated with outcomes and Sunitinib response in patients with clear cell renal cell carcinoma.

Autor: Yuan, Huiyang¹ (AUTHOR), Qin, Xin¹ (AUTHOR), Yang, Qingya¹ (AUTHOR), Liu, Li² (AUTHOR), Fang, Zhiqing¹ (AUTHOR) doctor_fangzq@sdu.edu.cn, Fan, Yidong¹ (AUTHOR) fanyd@sdu.edu.cn, Xu, Dawei³ (AUTHOR) Dawei.Xu@ki.se

Publikováno v: Biology of Sex Differences. 7/11/2023, Vol. 14 Issue 1, p1-16. 16p.

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Telomerase RNA component lncRNA as potential diagnostic biomarker promotes CRC cellular migration and apoptosis evasion via modulation of β-catenin protein level

Autor: Mohamed Bakr, Mai A. Abd-Elmawla, Hanan Elimam, Hebatallah Gamal El-Din, Amal Fawzy, Ahmed I. Abulsoud, Sherine M. Rizk

Publikováno v: Non-coding RNA Research, Vol 8, Iss 3, Pp 302-314 (2023)

Aim: Long non-coding RNA (LncRNA) telomerase RNA component (TERC) has telomerase-dependent and independent activity in numerous cancer types. The present study purposes to demonstrate the role of lncRNA TERC as a diagnostic serum biomarker in colorec

Externí odkaz: https://doaj.org/article/32971c03c80f463da5ef881e8d098a04

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Dyskerin and telomerase RNA component are sex-differentially associated with outcomes and Sunitinib response in patients with clear cell renal cell carcinoma

Autor: Huiyang Yuan, Xin Qin, Qingya Yang, Li Liu, Zhiqing Fang, Yidong Fan, Dawei Xu

Publikováno v: Biology of Sex Differences, Vol 14, Iss 1, Pp 1-16 (2023)

Abstract Background Clear cell renal cell carcinoma (ccRCC) displays sex-biased incidence, outcomes, molecular alterations and treatment efficacy; however, clinical managements are largely identical in male and female patients. Moreover, many biomark

Externí odkaz: https://doaj.org/article/4778c05e533a47f4b32da7b57de2b53b

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Human telomerase RNA component (hTERC) gene expression and chromosome 7 ploidy correlate positively with histological grade of cervical intraepithelial neoplasia.

Autor: Aggarwal, Divya¹ (AUTHOR), Wadhwa, Neelam¹ (AUTHOR) drneelam428@yahoo.co.in, Arora, Tanvi¹ (AUTHOR), Rajaram, Shalini² (AUTHOR), Diwaker, Preeti¹ (AUTHOR), Halder, Ashutosh³ (AUTHOR), Jain, Manish³ (AUTHOR), Mishra, Kiran¹ (AUTHOR)

Publikováno v: Cytopathology. Sep2021, Vol. 32 Issue 5, p631-639. 9p.

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Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence.

Autor: Lekva, Tove¹ (AUTHOR) tove.lekva@ous-research.no, Roland, Marie Cecilie Paasche^2,3 (AUTHOR), Estensen, Mette E.⁴ (AUTHOR), Norwitz, Errol R.⁵ (AUTHOR), Tilburgs, Tamara^6,7 (AUTHOR), Henriksen, Tore^2,8 (AUTHOR), Bollerslev, Jens^8,9 (AUTHOR), Normann, Kjersti R.^8,9 (AUTHOR), Magnus, Per¹⁰ (AUTHOR), Olstad, Ole Kristoffer¹¹ (AUTHOR), Aukrust, Pål^1,8,12,13,14 (AUTHOR), Ueland, Thor^1,8,13,14 (AUTHOR)

Publikováno v: Scientific Reports. 11/15/2021, Vol. 11 Issue 1, p1-9. 9p.

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Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence

Autor: T. Lekva, M. C. P. Roland, M. E. Estensen, E. R. Norwitz, T. Tilburgs, T. Henriksen, J. Bollerslev, K. R. Normann, P. Magnus, O. K. Olstad, P. Aukrust, T. Ueland

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract Senescence in placenta/fetal membranes is a normal phenomenon linked to term parturition. However, excessive senescence which may be induced by telomere attrition, has been associated with preeclampsia (PE). We hypothesized that the telomera

Externí odkaz: https://doaj.org/article/71ebd5ffe5f54d9cbc9e34dbe0b359d1

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Cytotoxic effect of combining two antisense oligonucleotides against telomerase rna component (hTR and mRNA of centromere protein B (CENP-B) in hepatocellular carcinoma cells

Autor: AHMED M. EL-DESOKY, YASSER B.M. ALI, ROBA M. TALAAT

Publikováno v: Anais da Academia Brasileira de Ciências, Vol 94, Iss 2 (2022)

Abstract Telomerase is a ribonucleoprotein enzyme that plays a crucial role in maintaining the malignancy and is responsible for cellular immortality and tumorigenesis. On another hand, Centromere protein B (CENP-B) plays an important role in cell cy

Externí odkaz: https://doaj.org/article/7f2f939dc5534dd1a0a225058abcc69d

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