Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Telomerase/*metabolism"'
Autor:
Martin J. Humphries, Paul N. Bishop, Nadhim Bayatti, Maja Søberg Udsen, Rawshan Choudhury, Viranga Tilakaratna, Selina McHarg, Richard Scharff, Ewa Szula, Simon J. Clark, Janet A. Askari
Publikováno v:
Scientific Reports
Choudhury, R, Bayatti, N, Scharff, R, Szula, E, Tilakaratna, V, Udsen, M, Mcharg, S, Askari, J, Humphries, M J, Bishop, P & Clark, S 2021, ' FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress ', Scientific Reports, vol. 11, no. 1, 14175 . https://doi.org/10.1038/s41598-021-93708-5
Choudhury, R, Bayatti, N, Scharff, R, Szula, E, Tilakaratna, V, Udsen, M S, McHarg, S, Askari, J A, Humphries, M J, Bishop, P N & Clark, S J 2021, ' FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress ', Scientific Reports, vol. 11, 14175 . https://doi.org/10.1038/s41598-021-93708-5
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Choudhury, R, Bayatti, N, Scharff, R, Szula, E, Tilakaratna, V, Udsen, M, Mcharg, S, Askari, J, Humphries, M J, Bishop, P & Clark, S 2021, ' FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress ', Scientific Reports, vol. 11, no. 1, 14175 . https://doi.org/10.1038/s41598-021-93708-5
Choudhury, R, Bayatti, N, Scharff, R, Szula, E, Tilakaratna, V, Udsen, M S, McHarg, S, Askari, J A, Humphries, M J, Bishop, P N & Clark, S J 2021, ' FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress ', Scientific Reports, vol. 11, 14175 . https://doi.org/10.1038/s41598-021-93708-5
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Retinal pigment epithelial (RPE) cells that underlie the neurosensory retina are essential for the maintenance of photoreceptor cells and hence vision. Interactions between the RPE and their basement membrane, i.e. the inner layer of Bruch’s membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd44c6c515f5cf3e410767874f2acb8
https://pubmed.ncbi.nlm.nih.gov/34239032
https://pubmed.ncbi.nlm.nih.gov/34239032
Publikováno v:
Genes and Development, Vol. 21, No 3 (2007) pp. 292-302
Eukaryotic cells distinguish their chromosome ends from accidental DNA double-strand breaks by packaging them in a protective structure referred to as the telomere “cap.” Here we investigate the nature of the telomere cap by examining events at D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d35cf8d1e33b01bc6bc68548f7f8a1
https://doi.org/10.1101/gad.400907
https://doi.org/10.1101/gad.400907
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0132977 (2015)
Plos One, vol. 10, no. 7, pp. e0132977
PLoS ONE, Vol 10, Iss 7, p e0132977 (2015)
Plos One, vol. 10, no. 7, pp. e0132977
Cancer stem cells are cancer cells characterized by stem cell properties and represent a small population of tumor cells that drives tumor development, progression, metastasis and drug resistance. To date, the molecular mechanisms that generate and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9aa14861e46190093ecad6aac38b12
http://europepmc.org/articles/PMC4506091
http://europepmc.org/articles/PMC4506091
Autor:
Dimitrios Loutradis, N. Kanakas, G. Makrydimas, Nikolaos Sofikitis, Ikuo Miyagawa, K. Tsoukanelis, Dimitrios Baltogiannis, Dimitrios Giannakis
Publikováno v:
Andrologia. 36:111-122
We evaluated the reproductive potential of frozen/thawed testicular spermatozoa of azoospermic men with left varicocele. The role of testicular tissue telomerase assay (TTA) in the prediction of the presence of testicular spermatozoa pre- and post-va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff8978abe232ddd2ea458866c1b15a9
https://doi.org/10.1111/j.1439-0272.2004.00615.x
https://doi.org/10.1111/j.1439-0272.2004.00615.x
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
instname
The presence of telomerase activity has been analyzed in almost all tumor types and tumor-derived cell lines. However, there are very few studies that focus on the presence of telomerase activity in bone tumors, and most of them report analysis on ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2516e2c161d2ac8a564e0e51d55d27e8
https://doi.org/10.1203/01.pdr.0000102455.36737.3c
https://doi.org/10.1203/01.pdr.0000102455.36737.3c
Autor:
Takahiro Taira, Taro Kanaya, Masahiro Takakura, Masaki Inoue, Masuo Yutsudo, Hiroyoshi Ariga, Hideaki Itoh, Satoru Kyo
Publikováno v:
Nucleic Acids Research. 28:669-677
Telomerase activation is thought to be a critical step in cellular immortalization and carcinogenesis. The human telomerase catalytic subunit (hTERT) is a rate limiting determinant of the enzymatic activity of human telomerase. In the previous study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d10baa0badf2bd8c3fd707167dcb549
https://doi.org/10.1093/nar/28.3.669
https://doi.org/10.1093/nar/28.3.669
Autor:
Neal F. Lue, Chantal Autexier
This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase.
Autor:
Martin J. S. Dyer, Douglas E. Horsman, Monika Szczepanowski, Ole Ammerpohl, Wolfram Klapper, Randy D. Gascoyne, Jose A. Martinez-Climent, Stephan Stilgenbauer, José I. Martín-Subero, Takashi Akasaka, Aneela Majid, Evelyne Callet-Bauchu, Lana Harder, Reiner Siebert, Holger Tönnies, Stefan Gesk, Inga Nagel
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
instname
Sequence variants at the TERT-CLPTM1L locus in chromosome 5p have been recently associated with disposition for various cancers. Here we show that this locus including the gene encoding the telomerase reverse-transcriptase TERT at 5p13.33 is rarely b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056b691d521a3a66bafc32545cc46c81
https://pubmed.ncbi.nlm.nih.gov/20460502
https://pubmed.ncbi.nlm.nih.gov/20460502
Autor:
Sabine Tejpar, Fred T. Bosman, Pu Yan, Roberto Fiocca, Arnaud Roth, Richard D. Kennedy, Daniel Dietrich, Eric Van Cutsem
Publikováno v:
Clinical Cancer Research, Vol. 15, No 17 (2009) pp. 5528-33
Purpose: We evaluated the feasibility of biomarker development in the context of multicenter clinical trials. Experimental Design: Formalin-fixed, paraffin-embedded (FFPE) tissue samples were collected from a prospective adjuvant colon cancer trial (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c86d32d135007454af2b7690a10635
http://hdl.handle.net/11567/217712
http://hdl.handle.net/11567/217712
Autor:
Michael A. Grotzer, Christoph Oehler-Jänne, Tarek Shalaby, Martin Pruschy, Alexandre Arcaro, Duncan Stearns, Charles G. Eberhart, Lucia Arnold, André O. von Bueren
Publikováno v:
BMC Cancer
BMC cancer, Vol. 9 (2009) P. 10
von Bueren, André O; Shalaby, Tarek; Oehler-Jänne, Christoph; Arnold, Lucia; Stearns, Duncan; Eberhart, Charles G; Arcaro, Alexandre; Pruschy, Martin; Grotzer, Michael A (2009). RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio-and chemotherapy in childhood medulloblastoma cells. BMC cancer, 9, p. 10. London: BioMed Central 10.1186/1471-2407-9-10
BMC Cancer, Vol 9, Iss 1, p 10 (2009)
BMC cancer, Vol. 9 (2009) P. 10
von Bueren, André O; Shalaby, Tarek; Oehler-Jänne, Christoph; Arnold, Lucia; Stearns, Duncan; Eberhart, Charles G; Arcaro, Alexandre; Pruschy, Martin; Grotzer, Michael A (2009). RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio-and chemotherapy in childhood medulloblastoma cells. BMC cancer, 9, p. 10. London: BioMed Central 10.1186/1471-2407-9-10
BMC Cancer, Vol 9, Iss 1, p 10 (2009)
BackgroundWith current treatment strategies, nearly half of all medulloblastoma (MB) patients die from progressive tumors. Accordingly, the identification of novel therapeutic strategies remains a major goal. Deregulation of c-MYC is evident in numer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6876b3be6926450ad1dd12ea1060409
https://doi.org/10.5167/uzh-28400
https://doi.org/10.5167/uzh-28400