Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Telma S. Martins"'
Autor:
Telma S. Martins, Miguel Correia, Denise Pinheiro, Carolina Lemos, Marta Vaz Mendes, Clara Pereira, Vítor Costa
Publikováno v:
Cells, Vol 13, Iss 8, p 655 (2024)
The Sit4 protein phosphatase plays a key role in orchestrating various cellular processes essential for maintaining cell viability during aging. We have previously shown that SIT4 deletion promotes vacuolar acidification, mitochondrial derepression,
Externí odkaz:
https://doaj.org/article/61fe05bfd68e4f5db6a4daf7bbe62a24
Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann–Pick Type C1
Autor:
Telma S. Martins, Rafaela S. Costa, Rita Vilaça, Carolina Lemos, Vitor Teixeira, Clara Pereira, Vítor Costa
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6221 (2023)
Niemann–Pick type C1 (NPC1) is an endolysosomal transmembrane protein involved in the export of cholesterol and sphingolipids to other cellular compartments such as the endoplasmic reticulum and plasma membrane. NPC1 loss of function is the major c
Externí odkaz:
https://doaj.org/article/b1b6c00091414908a26407bcb7105b09
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9017 (2021)
Lipid droplets (LDs) are ubiquitous organelles that fulfill essential roles in response to metabolic cues. The identification of several neutral lipid synthesizing and regulatory protein complexes have propelled significant advance on the mechanisms
Externí odkaz:
https://doaj.org/article/ba5b01138d9042dd86e21b2bf34361cf
Autor:
Ana Cláudia Leite, Telma S. Martins, Rute R. Cesário, Vitor Teixeira, Vítor Costa, Clara Pereira
Publikováno v:
Journal of cell science. 136(1)
Cdc28, the homolog of mammalian Cdk1, is a conserved key regulatory kinase for all major cell cycle transitions in yeast. We have found that defects in mitochondrial respiration (including deletion of ATP2, an ATP synthase subunit) inhibit growth of
Autor:
Ana Cláudia Leite, Rute R. Cesário, Telma S. Martins, Vitor Teixeira, Vítor Costa, Clara Pereira
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Molecular Microbiology. 109:422-432
Iron is an essential element for eukaryotes as it participates as a redox-active co-factor in many biological processes. Since iron is also potentially toxic, iron levels are carefully regulated. In the yeast Saccharomyces cerevisiae, iron homeostasi
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9017, p 9017 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 9017, p 9017 (2021)
Volume 22
Issue 16
Lipid droplets (LDs) are ubiquitous organelles that fulfill essential roles in response to metabolic cues. The identification of several neutral lipid synthesizing and regulatory protein complexes have propelled significant advance on the mechanisms
Autor:
Clara Pereira, Francesc Posas, Pedro Moradas-Ferreira, Telma S. Martins, Vítor Costa, Vitor Hugo Teixeira, Rita Vilaça, Eulàlia de Nadal, David Canadell
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
instname
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Iron acquisition systems have to be tightly regulated to assure a continuous supply of iron, since it is essential for survival, but simultaneously to prevent iron overload that is toxic to the cells. In budding yeast, the low‑iron sensing transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72e47305a58ebad68be6d69197e3c91
https://hdl.handle.net/10216/109383
https://hdl.handle.net/10216/109383