Lack of impact of protease inhibitor resistance-associated mutations on the outcome of HIV-1-infected patients switching to darunavir-based dual therapy

Autor: Vizcarra, P, Blanco, JL, Montejano, R, Negredo, E, Espinosa, N, Casado, JL, Monsalvo, M, Bernardino, JI, Puig, J, Montero, M, Castro, I, Mena, A, Castro, A, Palacios, R, de Quiros, JCLB, Tejerina, F, Latorre, LP, Ramirez, M, Vergas, J, Tellez, MJ, Galindo, P, Vilalta, RF, Cabello, A, Deltoro, MG, Cuevas, PR, de Santiago, AD, Moral, SD, BIRDi Study Grp

Publikováno v: Infectious Diseases
r-IGTP: Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Institut de Recerca Germans Trias i Pujol (IGTP)

Background: Little is known about the impact of baseline resistance-associated mutations (RAMs) on the outcomes of alternative therapeutic strategies such as dual regimens. We assessed the efficacy of boosted darunavir plus raltegravir (DRV + RAL) du

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::12e8cd5b03c163dc9b0e4d68ef4e5a9c
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=1329

Executive summary of the GeSIDA consensus document on control and monitoring of HIV-infected patients

Autor: Crespo, M, Lozano, F, Buzon, MJ, Curran, A, Estrada, V, Garcia, F, Imaz, A, Cortes, LL, Losa, JE, Masia, M, Merchante, N, Marino, A, Ocampo, A, Perez-Molina, JA, Poveda, E, Riera, M, Santin, M, Santos, J, Valencia, E, Arazo, P, de la Torre, J, Aldeguer, JL, Palacios, R, Rivero, A, Rubio, R, Sanz, J, Tellez, MJ

Publikováno v: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

The continuous increase in our knowledge of HIV medicine and antiretroviral treatment has led us to draft specific consensus documents focused on topics other than antiretroviral therapy, such as treatment of opportunistic diseases, pre- and post-exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::1cd724edd8e85f540ba4ad40e276186a
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=11282

Dual Therapy With Darunavir and Ritonavir Plus Lamivudine vs Triple Therapy With Darunavir and Ritonavir Plus Tenofovir Disoproxil Fumarate and Emtricitabine or Abacavir and Lamivudine for Maintenance of Human Immunodeficiency Virus Type 1 Viral Suppression: Randomized, Open-Label, Noninferiority DUAL-GESIDA 8014-RIS-EST45 Trial

Autor: Pulido, F, Ribera, E, Lagarde, M, Perez-Valero, I, Palacios, R, Iribarren, JA, Payeras, A, Domingo, P, Sanz, J, Cervero, M, Curran, A, Rodriguez-Gomez, FJ, Tellez, MJ, Ryan, P, Barrufet, P, Knobel, H, Rivero, A, Alejos, B, Yllescas, M, Arribas, JR

Publikováno v: CLINICAL INFECTIOUS DISEASES
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Background. Our objective was to assess the therapeutic noninferiority of dual therapy with darunavir/ritonavir and lamivudine compared to triple therapy with darunavir/ritonavir plus 2 nucleos(t)ides for maintenance of human immunodeficiency virus t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::865fff55d901455a872238034a71d45c
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4122

Human Immunodeficiency Virus/Hepatitis C Virus Coinfection in Spain: Prevalence and Patient Characteristics

Autor: Berenguer, J, Rivero, A, Jarrin, I, Nunez, MJ, Vivancos, MJ, Crespo, M, Tellez, MJ, Domingo, P, Iribarren, JA, Artero, A, Marquez, M, Santos, I, Moreno, J, Montero, M, Gonzalez-Garcia, J

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Open Forum Infectious Diseases
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau

Background. The purpose of this study was to assess the prevalence of anti-hepatitis C virus (HCV) antibodies (Abs) and active HCV infection in human immunodeficiency virus (HIV)-infected (HIV+) patients in Spain in 2015. This was a cross-sectional s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8036c88693738525a285279bcb16cd2c
https://hdl.handle.net/20.500.12530/26501

Bone mineral density and inflammatory and bone biomarkers after darunavir-ritonavir combined with either raltegravir or tenofovir-emtricitabine in antiretroviral-naive adults with HIV-1: a substudy of the NEAT001/ANRS143 randomised trial

Autor: Bernardino, J. I., Mocroft, A., Mallon, P. W., Wallet, C., Gerstoft, J., Russell, C., Reiss, P., Katlama, C., De Wit, S., Richert, L., Babiker, A., Buno, A., Castagna, A., Girard, P. -M., Chene, G., Raffi, F., Arribas, J. R., Dedes, N, Chene, G, Richert, L, Allavena, C, Raffi, F, Autran, B, Antinori, A, Bucciardini, R, Vella, S, Horban, A, Arribas, J, Babiker, Ag, Boffito, M, Pillay, D, Pozniak, A, Franquet, X, Schwarze, S, Grarup, J, Fischer, A, Wallet, C, Diallo, A, Molina, Jm, Saillard, J, Moecklinghoff, C, Stellbrink, Hj, Van Leeuwen, R, Gatell, J, Sandstrom, E, Flepp, M, Ewings, F, George, Ec, Hudson, F, Pearce, G, Quercia, R, Rogatto, F, Leavitt, R, Nguyen, By, Goebel, F, Marcotullio, S, Babiker, A, Kaur, N, Sasieni, P, Spencer-Drake, C, Peto, T, Miller, V, Chêne, G, Arnault, F, Boucherie, C, Jean, D, Paniego, V, Paraina, F, Rouch, E, Schwimmer, C, Soussi, M, Taieb, A, Termote, M, Touzeau, G, Cursley, A, Dodds, W, Hoppe, A, Kummeling, I, Pacciarini, F, Paton, N, Russell, C, Taylor, K, Ward, D, Aagaard, B, Eid, M, Gey, D, Jensen, Bg, Jakobsen, Ml, Jansson, Po, Jensen, K, Joensen, Zm, Larsen, Em, Pahl, C, Pearson, M, Nielsen, Br, Reilev, Ss, Christ, I, Lathouwers, D, Mendy, By, Metro, A, Couffin-Cadiergues, S, Knellwolf, Al, Palmisiano, L, Aznar, E, Barea, C, Cotarelo, M, Esteban, H, Girbau, I, Moyano, B, Ramirez, M, Saiz, C, Sanchez, I, Yllescas, M, Binelli, A, Colasanti, V, Massella, M, Anagnostou, O, Gioukari, V, Touloumi, G, Schmied, B, Rieger, A, Vetter, N, De Wit, S, Florence, E, Vandekerckhove, L, Gerstoft, J, Mathiesen, L, Katlama, C, Cabie, A, Cheret, A, Dupon, M, Ghosn, J, Girard, Pm, Goujard, C, Lévy, Y, Morlat, P, Neau, D, Obadia, M, Perre, P, Piroth, L, Reynes, J, Tattevin, P, Ragnaud, Jm, Weiss, L, Yazdan, Y, Yeni, P, Zucman, D, Behrens, G, Esser, S, Fätkenheuer, G, Hoffmann, C, Jessen, H, Rockstroh, J, Schmidt, R, Stephan, C, Unger, S, Hatzakis, A, Daikos, Gl, Papadopoulos, A, Skoutelis, A, Banhegyi, D, Mallon, P, Mulcahy, F, Andreoni, M, Bonora, S, Castelli, F, Monforte, Ad, Di Perri, G, Galli, M, Lazzarin, A, Mazzotta, F, Carlo, T, Vullo, V, Prins, J, Richter, C, Verhagen, D, Van Eeden, A, Doroana, M, Antunes, F, Maltez, F, Sarmento-Castro, R, Gonzalez Garcia, J, López Aldeguer, J, Clotet, B, Domingo, P, Gatell, Jm, Knobel, H, Marquez, M, Pilar Miralles, M, Portilla, J, Soriano, V, Tellez, Mj, Thalme, A, Blaxhult, A, Gisslen, M, Winston, A, Fox, J, Gompels, M, Herieka, E, Johnson, M, Leen, C, Teague, A, Williams, I, Boyd, Ma, Møller, Nf, Frøsig, E, Larsen, M, Le Moing, V, Wit, Fw, Kowalska, J, Berenguer, J, Moreno, S, Müller, Nj, Török, E, Post, F, Angus, B, Calvez, V, Boucher, C, Collins, S, Dunn, D, Lambert, S, Marcelin, Ag, Perno, Cf, White, E, Ammassari, A, Stoehr, W, Schmidt, Re, Odermarsky, M, Smith, C, Thiébaut, R, De La Serna JI, Castagna, A, Furrer, Hj, Mocroft, A, Reiss, P, Fragola, V, Lauriola, M, Murri, R, Nieuwkerk, P, Spire, B, Volny-Anne, A, West, B, Amieva, H, Codina, Jm, Braggion, Marco, Focà, E

Publikováno v: Lancet HIV, 2(11), e464-e473. Elsevier Limited

Osteopenia, osteoporosis, and low bone mineral density are frequent in patients with HIV. We assessed the 96 week loss of bone mineral density associated with a nucleoside or nucleotide reverse transcriptase inhibitor (NtRTI)-sparing regimen. Antiret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5e9b84f981ecb6a9c35467e85af3e9