Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Teklu Egnuni"'
Autor:
Chiara Galloni, Teklu Egnuni, Safoura Zahed Mohajerani, Jiaqi Ye, Sibylle Mittnacht, Valerie Speirs, Mihaela Lorger, Georgia Mavria
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The role of endothelial cells in promoting cancer cell extravasation to the brain during the interaction of cancer cells with the vasculature is not well characterised. We show that brain endothelial cells activate EGFR signalling in triple-
Externí odkaz:
https://doaj.org/article/cd26aee6a2a548fb9ca20940a8ec9c7a
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1651 (2021)
Gold nanoparticles have been indicated for use in a diagnostic and/or therapeutic role in several cancer types. The use of gold nanorods (AuNRs) with a surface plasmon resonance (SPR) in the second near-infrared II (NIR-II) optical window promises de
Externí odkaz:
https://doaj.org/article/f1c248e9916e45148bab3337cc0dc368
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1651, p 1651 (2021)
Volume 13
Issue 10
Pharmaceutics, Vol 13, Iss 1651, p 1651 (2021)
Volume 13
Issue 10
Gold nanoparticles have been indicated for use in a diagnostic and/or therapeutic role in several cancer types. The use of gold nanorods (AuNRs) with a surface plasmon resonance (SPR) in the second near-infrared II (NIR-II) optical window promises de
Publikováno v:
The Journal of the Acoustical Society of America. 152:A224-A224
The use of plasmonic gold nanoparticles (AuNP) that have been actively targeted to a specific tumour region is a highly active area of research for both drug delivery and hypothermia applications. One application is providing in situ cavitation nucle
Hematopoietic Stem Cell Gene Therapy for Brain Metastases Using Myeloid Cell–Specific Gene Promoters
Autor:
Ryan K. Mathew, Ashley Sunderland, Alastair Droop, Christopher Fife, Jennifer Williams, Nora Rippaus, Stephanie Cherqui, Tereza Andreou, Teklu Egnuni, Yolanda D Kartika, David Taggart, Sheri L. Holmen, Krzysztof Wronski, Mihaela Lorger, Rebecca J Brownlie
Publikováno v:
Journal of the National Cancer Institute, vol 112, iss 6
JNCI Journal of the National Cancer Institute
JNCI Journal of the National Cancer Institute
Background Brain metastases (BrM) develop in 20–40% of cancer patients and represent an unmet clinical need. Limited access of drugs into the brain because of the blood-brain barrier is at least partially responsible for therapeutic failure, necess
Publikováno v:
The Journal of the Acoustical Society of America. 145:1810-1811
High intensity focused ultrasound (HIFU) is a non-invasive and non-ionising approach used primarily for the thermal ablation of cancerous tumours. Even though it has been in clinical use for over 30 years, it has yet to achieve widespread use. Two ke
Autor:
Harry O, King, Tim, Brend, Helen L, Payne, Alexander, Wright, Thomas A, Ward, Karan, Patel, Teklu, Egnuni, Lucy F, Stead, Anjana, Patel, Heiko, Wurdak, Susan C, Short
Publikováno v:
Stem Cell Reports
Summary Patients with glioblastoma die from local relapse despite surgery and high-dose radiotherapy. Resistance to radiotherapy is thought to be due to efficient DNA double-strand break (DSB) repair in stem-like cells able to survive DNA damage and
Autor:
Susan C Short, Teklu Egnuni
Publikováno v:
Neuro-Oncology. 19:iii25-iii25
Introduction: Invasion and growth of brain tumours require cooperation of the tumour cell and endothelial cell compartments. Limited efficacy of anti-angiogenic therapy in glioblastoma is associated with activation of VEGF independent mechanisms, and
Autor:
Annika Kyburz, Bruno Oesch, Mitchell V. Palmer, Ray Waters, Martin Vordermeier, Teklu Egnuni, Alex Raeber, Irene Schiller, R. Hardegger
Publikováno v:
Veterinary Immunology and Immunopathology. 128:230-231