Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Teki S. Hegwood"'
Publikováno v:
Neurochemical Research. 17:125-128
Using synaptosomes prepared from whole rat brain, the spontaneous, calcium-independent, and calcium-dependent release of glutamate and GABA was assessed. Time intervals of 1-30 seconds were studied. Spontaneous release of glutamate (but not GABA) was
Publikováno v:
Biological Psychiatry. 30:1191-1198
Previous studies from our laboratory indicated that the veratridine-induced release of glutamate and GABA from synaptosomes derived from brains of schizophrenics was decreased. In the present study, synaptosomes were prepared from frozen brain sample
Publikováno v:
Psychiatry Research. 37:261-270
In several previous studies, we reported significantly higher plasma serine concentrations in psychotic (and schizophrenic) subjects compared with nonpsychotic and control subjects. In those studies, we used a gas chromatopgraphy technique to assay t
Publikováno v:
Neuroscience Letters. 121:77-80
Studies of amino acid release were carried out using frozen sections from brains of schizophrenics and controls. Synaptosomes were prepared via differential centrifugation in Ficoll allowing the veratridine-induced release of aspartate, glutamate, gl
Publikováno v:
Neuroscience Letters. 120:237-240
We studied the kinetics of the enzyme serine hydroxymethyl transferase (SHMT) and the concentration of its metabolic substrates serine and glycine, in the postmortem brains of controls and schizophrenics. The Km of SHMT, and the concentration of seri