Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tek N Lamichhane"'
Autor:
Aneeshkumar G Arimbasseri, Nathan H Blewett, James R Iben, Tek N Lamichhane, Vera Cherkasova, Markus Hafner, Richard J Maraia
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005671 (2015)
Control of the differential abundance or activity of tRNAs can be important determinants of gene regulation. RNA polymerase (RNAP) III synthesizes all tRNAs in eukaryotes and it derepression is associated with cancer. Maf1 is a conserved general repr
Externí odkaz:
https://doaj.org/article/01de7100725b45bfaa58d81518ea2af8
Autor:
John W Yarham, Tek N Lamichhane, Angela Pyle, Sandy Mattijssen, Enrico Baruffini, Francesco Bruni, Claudia Donnini, Alex Vassilev, Langping He, Emma L Blakely, Helen Griffin, Mauro Santibanez-Koref, Laurence A Bindoff, Ileana Ferrero, Patrick F Chinnery, Robert McFarland, Richard J Maraia, Robert W Taylor
Publikováno v:
PLoS Genetics, Vol 10, Iss 6, p e1004424 (2014)
Identifying the genetic basis for mitochondrial diseases is technically challenging given the size of the mitochondrial proteome and the heterogeneity of disease presentations. Using next-generation exome sequencing, we identified in a patient with s
Externí odkaz:
https://doaj.org/article/1dc0aee73401425cac39fb13446d4bfd
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Extracellular vesicles (EVs), such as exosomes, have been identified as regulators of vascular remodeling and have promise as therapeutics for vascularization applications. Towards development of EVs as therapeutics, it has been demonstrated
Externí odkaz:
https://doaj.org/article/b0e1adb5d70d429f8324fe85298d360b
Autor:
H. William S. Lawrence, Kenneth S. Plante, Divya Mirchandani, Alexander Tibbens, Eryu Wang, Jason E. Comer, Igor S. Lukashevich, Jennifer E. Peel, Tek N. Lamichhane, Irina Tretyakova, Peter Pushko, Shannan L. Rossi, Scott C. Weaver, Sif Gudjohnsen
Publikováno v:
Vaccine. 38:3378-3386
Live-attenuated V4020 vaccine for Venezuelan equine encephalitis virus (VEEV) containing attenuating rearrangement of the virus structural genes was evaluated in a non-human primate model for immunogenicity and protective efficacy against aerosol cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce46193d6cfda274e97143cc74a3232
https://doi.org/10.1016/j.vaccine.2020.02.007
https://doi.org/10.1016/j.vaccine.2020.02.007
Autor:
Wei Chao, Eshan Dahal, Stephanie M. Kronstadt, Daniel Levy, Lin Zou, Daphne R Knudsen, Steven M. Jay, Sheng Wang, Babita Parajuli, Anjana Jeyaram, Tek N. Lamichhane
Publikováno v:
Mol Ther
Based on their identification as physiological nucleic acid carriers in humans and other organisms, extracellular vesicles (EVs) have been explored as therapeutic delivery vehicles for DNA, RNA, and other cargo. However, efficient loading and functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415fe6ea3857f6912d7afaba398f5c41
https://doi.org/10.1016/j.ymthe.2019.12.007
https://doi.org/10.1016/j.ymthe.2019.12.007
Publikováno v:
Journal of Molecular Biology. 428:3615-3631
Interactions between ribosomal proteins (rproteins) and ribosomal RNA (rRNA) facilitate the formation of functional ribosomes. S15 is a central domain primary binding protein that has been shown to trigger a cascade of conformational changes in 16S r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f012fade2b9c29468915b085bb38f08
https://doi.org/10.1016/j.jmb.2016.05.010
https://doi.org/10.1016/j.jmb.2016.05.010
Autor:
Navein Arumugasaamy, Tek N. Lamichhane, John S. Schardt, Anjana Jeyaram, Babita Parajuli, Steven M. Jay, Natalie K. Livingston, Divya Patel
Publikováno v:
Cellular and Molecular Bioengineering. 9:315-324
Extracellular vesicles (EVs), including exosomes and microvesicles, have emerged as promising drug delivery vehicles for small RNAs (siRNA and miRNA) due to their natural role in intercellular RNA transport. However, the application of EVs for therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350483e9736f4b798820ea6f94a4b52a
https://doi.org/10.1007/s12195-016-0457-4
https://doi.org/10.1007/s12195-016-0457-4
Autor:
Tek N. Lamichhane, Steven M. Jay
Publikováno v:
Targeted Drug Delivery ISBN: 9781493986590
Extracellular vesicles (EVs) are biological nanoparticles comprising exosomes, microvesicles, and other heterogeneous nanoscopic vesicle populations that are produced by most cell types. In addition to their putative roles as critical mediators of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae648fe12fb105cec5fe150fa299667d
https://doi.org/10.1007/978-1-4939-8661-3_4
https://doi.org/10.1007/978-1-4939-8661-3_4
Autor:
Steven M. Jay, Sonja Sokic, Rahul S. Raiker, Tek N. Lamichhane, Jennifer W. Lin, John S. Schardt
Publikováno v:
Tissue Engineering Part B: Reviews. 21:45-54
Extracellular vesicles (EVs)—comprising a heterogeneous population of cell-derived lipid vesicles including exosomes, microvesicles, and others—have recently emerged as both mediators of intercellular information transfer in numerous biological s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1005612db516247f5883b2a2a634c1fb
https://doi.org/10.1089/ten.teb.2014.0300
https://doi.org/10.1089/ten.teb.2014.0300
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Extracellular vesicles (EVs), such as exosomes, have been identified as regulators of vascular remodeling and have promise as therapeutics for vascularization applications. Towards development of EVs as therapeutics, it has been demonstrated that phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1336d0a52824de7057a8130577eedef2
http://europepmc.org/articles/PMC5653762
http://europepmc.org/articles/PMC5653762