Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Tejeshwar Jain"'
Autor:
Prateek Sharma, MBBS, Tejeshwar Jain, MBBS, Vrishketan Sethi, MBBS, Srikanth Iyer, PhD, Vikas Dudeja, MD
Publikováno v:
Journal of Pancreatology, Vol 3, Iss 4, Pp 181-187 (2020)
Abstract. The fascinating hypothesis that microbes lead to cancer has long been dwelled upon but has only been recently investigated in cancers other than those of stomach and colon. Microbes can affect cancer cells directly through toxins or metabol
Externí odkaz:
https://doaj.org/article/ed5fdd21ecd848acb64bad5aeb43431d
Autor:
Ejas Palathingal Bava, John George, Mohammad Tarique, Srikanth Iyer, Preeti Sahay, Beatriz Gomez Aguilar, Dujon B. Edwards, Bhuwan Giri, Vrishketan Sethi, Tejeshwar Jain, Prateek Sharma, Utpreksha Vaish, Harrys K. C. Jacob, Anthony Ferrantella, Craig L. Maynard, Ashok K. Saluja, Rajinder K. Dawra, Vikas Dudeja
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Despite decades of research, there is no specific therapy for acute pancreatitis (AP). In the current study, we have evaluated the efficacy of pirfenidone, an antiinflammatory and antifibrotic agent that is approved by the FDA for treatment of idiopa
Externí odkaz:
https://doaj.org/article/5a67edc6225d42e6a846bf7637ca2d15
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The past decade has witnessed groundbreaking advances in the field of microbiome research. An area where immense implications of the microbiome have been demonstrated is tumor biology. The microbiome affects tumor initiation and progression through d
Externí odkaz:
https://doaj.org/article/fc4e91da779f46ceafe9e889352d0c61
Autor:
Bhuwan Giri, Prateek Sharma, Tejeshwar Jain, Anthony Ferrantella, Utpreksha Vaish, Siddharth Mehra, Bharti Garg, Srikanth Iyer, Vrishketan Sethi, Zoe Malchiodi, Rossana Signorelli, Harrys K.C Jacob, John George, Preeti Sahay, Ejas P. Bava, Rajinder Dawra, Sundaram Ramakrishnan, Ashok Saluja, Vikas Dudeja
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Heat shock protein 70 (Hsp70), a protein chaperone, is known to promote cell survival and tumor progression. However, its role in the tumor microenvironment (TME) is largely unknown. We specifically evaluated Hsp70 in the TME by implanting tumors in
Externí odkaz:
https://doaj.org/article/786c93290f6148c7ab4cff987558f4d1
Publikováno v:
EBioMedicine, Vol 56, Iss , Pp 102787- (2020)
Externí odkaz:
https://doaj.org/article/43d00f6044bc4a5f991c8a1722b44951
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13408 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related morbidity and mortality in the western world, with limited therapeutic strategies and dismal long-term survival. Cancer-associated fibroblasts (CAFs) are key components of t
Externí odkaz:
https://doaj.org/article/bfdf0bdd58f343588b375e71b00d3c34
Autor:
Tejeshwar Jain, Prateek Sharma, Bhuwan Giri, Srikanth Iyer, Vrishketan Sethi, Ejas P. Bava, Utpreksha Vaish, Preeti Sahay, Jashodeep Datta, Sushanth Reddy, John Bart Rose, Anam Khan, Nipun Merchant, Suresh T. Chari, Vikas Dudeja
Publikováno v:
HPB. 24:1729-1737
Exocrine pancreatic insufficiency (EPI) is frequently seen in patients with pancreatic cancer (PDAC) and is thought to contribute to nutritional complications. While EPI can be pharmacologically temporized with pancreatic enzyme replacement therapy (
Autor:
Ejas Palathingal Bava, John George, Srikanth Iyer, Preeti Sahay, Mohammad Tarique, Tejeshwar Jain, Utpreksha Vaish, Bhuwan Giri, Prateek Sharma, Ashok K. Saluja, Rajinder K. Dawra, Vikas Dudeja
Publikováno v:
Pancreatology. 22:553-563
Chronic pancreatitis (CP) is an irreversible fibro-inflammatory disease of the pancreas with no current targeted therapy. Pirfenidone, an anti-fibrotic and anti-inflammatory drug, is FDA approved for treatment of Idiopathic Pulmonary Fibrosis (IPF).
Autor:
Tejeshwar Jain, Vikas Dudeja
Publikováno v:
Cancer Discov
Defining the complex role of the microbiome in colorectal cancer (CRC) and the discovery of novel, pro-tumorigenic microbes are areas of active investigation. In the present study, culturing and reassociation experiments revealed that toxigenic strai
Publikováno v:
Journal of Pancreatology, Vol 3, Iss 4, Pp 181-187 (2020)
The fascinating hypothesis that microbes lead to cancer has long been dwelled upon but has only been recently investigated in cancers other than those of stomach and colon. Microbes can affect cancer cells directly through toxins or metabolites. They