Mechano-dependent sorbitol accumulation supports biomolecular condensate.

Autor: Torrino S; Université Côte d'Azur, CNRS, INSERM, IPMC, IHU RespirERA, Valbonne, France. Electronic address: stephanie.torrino@univ-cotedazur.fr., Oldham WM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Tejedor AR; Department of Chemical Physics, Faculty of Chemical Sciences, Universidad Complutense de Madrid, 28040 Madrid, Spain; Cavendish Laboratory, Department of Physics, Maxwell Centre, University of Cambridge, J Thomson Avenue, Cambridge CB3 0HE, UK., Burgos IS; Department of Chemical Physics, Faculty of Chemical Sciences, Universidad Complutense de Madrid, 28040 Madrid, Spain; Cavendish Laboratory, Department of Physics, Maxwell Centre, University of Cambridge, J Thomson Avenue, Cambridge CB3 0HE, UK., Nasr L; Université Côte d'Azur, CNRS, INSERM, IPMC, IHU RespirERA, Valbonne, France., Rachedi N; Université Côte d'Azur, CNRS, INSERM, IPMC, IHU RespirERA, Valbonne, France., Fraissard K; Université Côte d'Azur, CNRS, INSERM, IPMC, IHU RespirERA, Valbonne, France., Chauvet C; Université Côte d'Azur, CNRS, INSERM, IPMC, IHU RespirERA, Valbonne, France., Sbai C; Université Côte d'Azur, CNRS, INSERM, IPMC, IHU RespirERA, Valbonne, France., O'Hara BP; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA., Abélanet S; Université Côte d'Azur, CNRS, INSERM, IPMC, Valbonne, France., Brau F; Université Côte d'Azur, CNRS, INSERM, IPMC, Valbonne, France., Favard C; Institut de Recherche en Infectiologie de Montpellier, CNRS UMR 9004, University of Montpellier, Montpellier, France., Clavel S; Université Côte d'Azur, CNRS, INSERM, IPMC, IHU RespirERA, Valbonne, France., Collepardo-Guevara R; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK; Department of Genetics, University of Cambridge, Downing Site, Cambridge CB2 3EH, UK., Espinosa JR; Department of Chemical Physics, Faculty of Chemical Sciences, Universidad Complutense de Madrid, 28040 Madrid, Spain; Cavendish Laboratory, Department of Physics, Maxwell Centre, University of Cambridge, J Thomson Avenue, Cambridge CB3 0HE, UK., Ben-Sahra I; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA., Bertero T; Université Côte d'Azur, CNRS, INSERM, IPMC, IHU RespirERA, Valbonne, France. Electronic address: thomas.bertero@univ-cotedazur.fr.

Publikováno v: Cell [Cell] 2024 Nov 16. Date of Electronic Publication: 2024 Nov 16.

Mechano-dependent sorbitol accumulation supports biomolecular condensate.

Autor: Torrino S, Oldham WM, Tejedor AR, Burgos IS, Rachedi N, Fraissard K, Chauvet C, Sbai C, O'Hara BP, Abélanet S, Brau F, Clavel S, Collepardo-Guevara R, Espinosa JR, Ben-Sahra I, Bertero T

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 25. Date of Electronic Publication: 2023 Jul 25.

Detailed dynamics of discrete Gaussian semiflexible chains with arbitrary stiffness along the contour.

Autor: Tejedor AR; Department of Chemical Engineering, Universidad Politécnica de Madrid, José Gutiérrez Abascal 2, 28006, Madrid, Spain., Tejedor JR; Faculty of Physics, Department of Theoretical Physics, Universidad Complutense de Madrid, Plaza de las Ciencias, Ciudad Universitaria, Madrid, 28040 Madrid, Spain., Ramírez J; Department of Chemical Engineering, Universidad Politécnica de Madrid, José Gutiérrez Abascal 2, 28006, Madrid, Spain.

Publikováno v: The Journal of chemical physics [J Chem Phys] 2022 Oct 28; Vol. 157 (16), pp. 164904.

Protein structural transitions critically transform the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it.

Autor: Tejedor AR; Department of Chemical Engineering, Universidad Politécnica de Madrid, José Gutiérrez Abascal 2, 28006, Madrid, Spain.; Maxwell Centre, Cavendish Laboratory, Department of Physics, University of Cambridge, J J Thomson Avenue, Cambridge, CB3 0HE, UK., Sanchez-Burgos I; Maxwell Centre, Cavendish Laboratory, Department of Physics, University of Cambridge, J J Thomson Avenue, Cambridge, CB3 0HE, UK., Estevez-Espinosa M; Maxwell Centre, Cavendish Laboratory, Department of Physics, University of Cambridge, J J Thomson Avenue, Cambridge, CB3 0HE, UK.; Department of Biochemistry, University College London, Gower Street, London, WC1E 6BT, UK., Garaizar A; Maxwell Centre, Cavendish Laboratory, Department of Physics, University of Cambridge, J J Thomson Avenue, Cambridge, CB3 0HE, UK., Collepardo-Guevara R; Maxwell Centre, Cavendish Laboratory, Department of Physics, University of Cambridge, J J Thomson Avenue, Cambridge, CB3 0HE, UK.; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.; Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, UK., Ramirez J; Department of Chemical Engineering, Universidad Politécnica de Madrid, José Gutiérrez Abascal 2, 28006, Madrid, Spain. jorge.ramirez@upm.es., Espinosa JR; Maxwell Centre, Cavendish Laboratory, Department of Physics, University of Cambridge, J J Thomson Avenue, Cambridge, CB3 0HE, UK. jr752@cam.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2022 Sep 29; Vol. 13 (1), pp. 5717. Date of Electronic Publication: 2022 Sep 29.

'RNA modulation of transport properties and stability in phase-separated condensates.

Autor: Tejedor AR; Department of Chemical Engineering, Universidad Politécnica de Madrid, Madrid, Spain., Garaizar A; Cavendish Laboratory, Maxwell Centre, Department of Physics, University of Cambridge, Cambridge, United Kingdom., Ramírez J; Department of Chemical Engineering, Universidad Politécnica de Madrid, Madrid, Spain. Electronic address: jorge.ramirez@upm.es., Espinosa JR; Cavendish Laboratory, Maxwell Centre, Department of Physics, University of Cambridge, Cambridge, United Kingdom. Electronic address: jr752@cam.ac.uk.

Publikováno v: Biophysical journal [Biophys J] 2021 Dec 07; Vol. 120 (23), pp. 5169-5186. Date of Electronic Publication: 2021 Nov 09.