Solubility Enhancement and Inhalation Delivery of Cyclodextrin-Based Inclusion Complex of Delamanid for Pulmonary Tuberculosis Treatment

Autor: Suyash M. Patil, Druva Sarika Barji, Tejashri Chavan, Kinjal Patel, Andrew J. Collazo, Vasudha Prithipaul, Aaron Muth, Nitesh K. Kunda

Publikováno v: AAPS PharmSciTech. 24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61cd71e021ab5c1b087f283022868cf9
https://doi.org/10.1208/s12249-023-02510-1

Effect of Spray Drying on Amorphization of Indomethacin Nicotinamide Cocrystals; Optimization, Characterization, and Stability Study

Autor: Hesham M. Tawfeek, Tejashri Chavan, Nitesh K. Kunda

Publikováno v: AAPS PharmSciTech. 21

Cocrystals have gained a lot of consideration regarding its superior role in enhancement of solubility and dissolution of the included API. Cocrystals could be converted to coamorphous systems via different techniques like milling and quench cooling;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc81b9b73b38b5b7cbae8af0655358ea
https://doi.org/10.1208/s12249-020-01732-x

Introduction to Nanomedicine in Drug Delivery

Autor: Pavan Muttil, Tejashri Chavan, Nitesh K. Kunda

Publikováno v: Mucosal Delivery of Drugs and Biologics in Nanoparticles ISBN: 9783030359096

Recent advances in the field of nanotechnology have given a boost to the academic researchers, the pharmaceutical and biomedical industry, allowing its use in drug delivery and medical diagnosis. Nanotechnology allows the formulation of drug delivery

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3170060b90fcc4da15ea5923fcea6d65
https://doi.org/10.1007/978-3-030-35910-2_1

Repurposing Bedaquiline for Effective Non-Small Cell Lung Cancer (NSCLC) Therapy as Inhalable Cyclodextrin-Based Molecular Inclusion Complexes

Autor: Aaron Muth, Mimansa Goyal, Rasha Elbatanony, Srikanth Kolluru, Tejashri Chavan, Vineela Parvathaneni, Nathan Vega, Vivek Gupta, Nitesh K. Kunda

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 4783, p 4783 (2021)
Volume 22
Issue 9

There is growing evidence that repurposed drugs demonstrate excellent efficacy against many cancers, while facilitating accelerated drug development process. In this study, bedaquiline (BDQ), an FDA approved anti-mycobacterial agent, was repurposed a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5296ff9f975fc95dc3018463b6788b
https://doi.org/10.3390/ijms22094783