Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tejashree Mahaddalkar"'
Publikováno v:
Cancer Letters. 490:44-53
Glioblastoma (GBM) is the most common primary brain tumor and is highly aggressive with a median survival of 15 months. We have previously shown that residual cells of GBM form multinucleated giant cells (MNGCs) showing a senescent phenotype, but eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeca22eb86690282f479a82ef5ad1bae
https://doi.org/10.1016/j.canlet.2020.06.023
https://doi.org/10.1016/j.canlet.2020.06.023
Autor:
Madhura Ketkar, Shilpee Dutt, Rahul Thorat, Jayant Sastri Goda, Jyothi Nair, Tejashree Mahaddalkar, Safiulla Basha Syed
Publikováno v:
Journal of cell science. 134(24)
Glioblastoma (GBM) has poor median survival due to its resistance to chemoradiotherapy, which results in tumor recurrence. Recurrent GBMs currently lack effective treatments. DUSP6 is known to be pro-tumorigenic and is upregulated in GBM. We show tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f117f36493f14d3cb3d96fd52eabdc2
https://pubmed.ncbi.nlm.nih.gov/34792128
https://pubmed.ncbi.nlm.nih.gov/34792128
Autor:
Ramakrishna V. Hosur, Sanith Cheriyamundath, Manu Lopus, Tejashree Mahaddalkar, Shreyada N. Save, Sinjan Choudhary
Publikováno v:
Biomedicine & Pharmacotherapy. 98:76-81
Triphala (Trl) is an ayurvedic formulation used for treating disorders of the digestive, respiratory, and nervous systems. Its anticancer properties have also been documented. We studied effects of Trl on tubulin, a target protein for several antican
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d544a256db6cdb45ec61d2ae2cb7799
https://doi.org/10.1016/j.biopha.2017.12.022
https://doi.org/10.1016/j.biopha.2017.12.022
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 353:368-375
Mono/di-heteroaryl-bora-diazaindacene (1–6) were synthesized and their photophysical, electrochemical properties and cytotoxicity of 6 against pancreatic cancer (PANC-1) cells were studied. A comparison of some of the properties with their position
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9186af44629599d043d53486d1e1e2d
https://doi.org/10.1016/j.jphotochem.2017.11.019
https://doi.org/10.1016/j.jphotochem.2017.11.019
Publikováno v:
Experimental Cell Research. 360:163-170
Gold nanoparticles have been investigated extensively for their molecular mechanisms of action and anticancer potential. We report a novel, tubulin-targeted antiproliferative mechanism of action of tryptone-stabilized gold nanoparticles (TsAuNPs). Ts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fe6161fd782379f89daaed143826aa
https://doi.org/10.1016/j.yexcr.2017.09.002
https://doi.org/10.1016/j.yexcr.2017.09.002
Publikováno v:
Biomedicine & Pharmacotherapy. 86:74-80
Noscapine is an alkaloid present in the latex of Papaver somniferum. It has been known for its anticancer efficacy and lack of severe toxicities to normal tissues. Structural alterations in noscapine core architecture have produced a number of potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e625807ac2cd6c7750119c05e3b4c3
https://doi.org/10.1016/j.biopha.2016.11.143
https://doi.org/10.1016/j.biopha.2016.11.143
Publikováno v:
International Journal of Neurooncology. 4:38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b101be0d5b3b91ffbdd4130dc261bfb
https://doi.org/10.4103/ijno.ijno_20_21
https://doi.org/10.4103/ijno.ijno_20_21
Autor:
Srinivas Kantevari, Naresh Kumar Manchukonda, Neha Mohanpuria, Tejashree Mahaddalkar, Sanith Cheriyamundath, Sinjan Choudhary, Manu Lopus
Publikováno v:
ChemistrySelect. 1:4313-4319
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1b3cd3ec1a55b716b85a86b2c242d1e
https://doi.org/10.1002/slct.201600959
https://doi.org/10.1002/slct.201600959
Insights into the structure and tubulin-targeted anticancer potential of N-(3-bromobenzyl) noscapine
Autor:
Balasubramanian Sridhar, Tejashree Mahaddalkar, Srinivas Kantevari, Sanith Cheriyamundath, Praveen Kumar Reddy Nagireddy, Manu Lopus
Publikováno v:
Pharmacological reports : PR. 71(1)
Background Noscapine is a non-narcotic, antitussive alkaloid isolated from plants of Papaveraceae family. This benzylisoquinoline alkaloid and its synthetic derivatives, called noscapinoids, are being evaluated for their anticancer potential. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08669c8393ce13ee6d8d6c0737b274f0
https://pubmed.ncbi.nlm.nih.gov/30465924
https://pubmed.ncbi.nlm.nih.gov/30465924
Publikováno v:
European Journal of Pharmacology. 760:154-162
Βeta-sitosterol (β-SITO), a phytosterol present in pomegranate, peanut, corn oil, almond, and avocado, has been recognized to offer health benefits and potential clinical uses. β-SITO is orally bioavailable and, as a constituent of edible natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d632226c9e37596607cfb537b4bae34e
https://doi.org/10.1016/j.ejphar.2015.04.014
https://doi.org/10.1016/j.ejphar.2015.04.014