Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Teisha J. Rowland"'
Autor:
Mary Quansah, Lisa Fetter, Autumn Fineran, Haley V. Colling, Keaton Silver, Teisha J. Rowland, Andrew J. Bonham
Publikováno v:
Biosensors, Vol 13, Iss 7, p 675 (2023)
To overcome early cancer detection challenges, diagnostic tools enabling more sensitive, rapid, and noninvasive detection are necessary. An attractive cancer target for diagnostic blood tests is human Ecto-NOX disulfide–thiol exchanger 2 (ENOX2), e
Externí odkaz:
https://doaj.org/article/ef37152d808c4c4d9efd3220fbe78c58
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2358-2374 (2020)
Telomerase reverse transcriptase (TERT) is pathologically expressed in the vast majority of human cancers, but the epigenetic regulation of its expression is only beginning to be understood. In particular, the active TERT gene in cancer cells has bee
Externí odkaz:
https://doaj.org/article/4c23442add58420e9abb7ec63386e033
Publikováno v:
Bioengineering, Vol 9, Iss 12, p 720 (2022)
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) can be differentiated into cardiomyocytes (hESC-CMs and iPSC-CMs, respectively), which hold great promise for cardiac regenerative medicine and disease modeling efforts. Ho
Externí odkaz:
https://doaj.org/article/3cedb041bdf7428eb0a0ed92f4ce2057
Autor:
Anna B. N. Nguyen, Marcos Maldonado, Dylan Poch, Tyler Sodia, Andrew Smith, Teisha J. Rowland, Andrew J. Bonham
Publikováno v:
Sensors, Vol 21, Iss 8, p 2671 (2021)
Although it is estimated that more than one million Americans have celiac disease (CD), it remains challenging to diagnose. CD, an autoimmune and inflammatory response following the ingestion of gluten-containing foods, has symptoms overlapping with
Externí odkaz:
https://doaj.org/article/0ad504842b594d26823e2b862e37ed98
Autor:
Rene L. Begay, BS, Charles A. Tharp, MD, August Martin, Sharon L. Graw, PhD, Gianfranco Sinagra, MD, Daniela Miani, MD, Mary E. Sweet, BA, Dobromir B. Slavov, PhD, Neil Stafford, MD, Molly J. Zeller, Rasha Alnefaie, Teisha J. Rowland, PhD, Francesca Brun, MD, Kenneth L. Jones, PhD, Katherine Gowan, Luisa Mestroni, MD, Deborah M. Garrity, PhD, Matthew R.G. Taylor, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 5, Pp 344-359 (2016)
A genetic etiology has been identified in 30% to 40% of dilated cardiomyopathy (DCM) patients, yet only 50% of these cases are associated with a known causative gene variant. Thus, in order to understand the pathophysiology of DCM, it is necessary to
Externí odkaz:
https://doaj.org/article/234247b2b5784c6fbf2ceca86cc593b3
Autor:
Ilaria Puggia, Marco Merlo, Giulia Barbati, Teisha J. Rowland, Davide Stolfo, Marta Gigli, Federica Ramani, Andrea Di Lenarda, Luisa Mestroni, Gianfranco Sinagra
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)
BackgroundThe long‐term progression of idiopathic dilated cardiomyopathy (DCM) in pediatric patients compared with adult patients has not been previously characterized. In this study, we compared outcome and long‐term progression of pediatric and
Externí odkaz:
https://doaj.org/article/b7515f9d276a414591932fee6a5918f5
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0972452f69a19ae9b2361418f9ae43d3
https://doi.org/10.1096/fasebj.2022.36.s1.r3570
https://doi.org/10.1096/fasebj.2022.36.s1.r3570
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 14, Iss 10, Pp 2358-2374 (2020)
Molecular Oncology, Vol 14, Iss 10, Pp 2358-2374 (2020)
In cancer, active expression of the TERT gene paradoxically correlates with a hypermethylated CpG island. Here, we show that in 833 cancer cell lines representing 23 tissue types, the proximal promoter contains conserved hypomethylation. In lines wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebef51aa8bbd67273941d86450810c5
http://europepmc.org/articles/PMC7530785
http://europepmc.org/articles/PMC7530785
Autor:
Dobromir Slavov, William J. McKenna, Marco Merlo, Marta Gigli, Matthew R.G. Taylor, Francesca Brun, Teisha J. Rowland, Gianfranco Sinagra, Giulia Barbati, Andrea Cocciolo, Sharon L. Graw, Mary E. Haywood, Davide Stolfo, Francisco G. La Rosa, Gaetano Morea, Alessandro Altinier, Federica Ramani, Matteo Dal Ferro, Ilaria Puggia, Luisa Mestroni
Publikováno v:
Journal of the American College of Cardiology. 74:1480-1490
Background Genotype-phenotype correlations in dilated cardiomyopathy (DCM) and, in particular, the effects of gene variants on clinical outcomes remain poorly understood. Objectives The purpose of this study was to investigate the prognostic role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f56884bc5647ba8a2ecdf3598a5f74
https://doi.org/10.1016/j.jacc.2019.06.072
https://doi.org/10.1016/j.jacc.2019.06.072
Publikováno v:
Proceedings of the National Academy of Sciences. 116:18488-18497
Telomerase is pathologically reactivated in most human cancers, where it maintains chromosomal telomeres and allows immortalization. Because telomerase reverse transcriptase (TERT) is usually the limiting component for telomerase activation, numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921e1428e7780e62308e07f1fd237203
https://doi.org/10.1073/pnas.1908275116
https://doi.org/10.1073/pnas.1908275116