Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Teiji Wada"'
Autor:
Yukie Kashima, Yosuke Togashi, Shota Fukuoka, Takahiro Kamada, Takuma Irie, Ayako Suzuki, Yoshiaki Nakamura, Kohei Shitara, Tatsunori Minamide, Taku Yoshida, Naofumi Taoka, Tatsuya Kawase, Teiji Wada, Koichiro Inaki, Masataka Chihara, Yukihiko Ebisuno, Sakiyo Tsukamoto, Ryo Fujii, Akihiro Ohashi, Yutaka Suzuki, Katsuya Tsuchihara, Hiroyoshi Nishikawa, Toshihiko Doi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Single-cell level analysis is powerful tool to assess the heterogeneity of cellular components in tumor microenvironments (TME). In this study, we investigated immune-profiles using the single-cell analyses of endoscopically- or surgically-r
Externí odkaz:
https://doaj.org/article/ed447e8d5e6c46eab303d092243a0a34
Autor:
Anri Aki, Kento Tanaka, Nobumi Nagaoka, Takako Kimura, Daichi Baba, Yoshikuni Onodera, Teiji Wada, Hiroaki Maeda, Toshiyuki Nakanishi, Toshinori Agatsuma, Tomoaki Komai
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 8, Pp 478-488 (2020)
Abstract ORAI1 constitutes the pore‐forming subunit of the calcium release‐activated calcium (CRAC) channel, which is responsible for store‐operated calcium entry into lymphocytes. It is known that ORAI1 is essential for the activation of T cel
Externí odkaz:
https://doaj.org/article/052ac0ac4d254d4e9eaa0cf0d935e02f
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0222280 (2019)
[Fam-] trastuzumab deruxtecan (DS-8201a) is a HER2 (ERBB2)-targeting antibody-drug conjugate, composed of a HER2-targeting antibody and a topoisomerase I inhibitor, exatecan derivative, that has antitumor effects in preclinical xenograft models and c
Externí odkaz:
https://doaj.org/article/53172c713f324278a89fb65d32d77e54
Autor:
Daniel Andritschke, Sabrina Dilling, Mario Emmenlauer, Tobias Welz, Fabian Schmich, Benjamin Misselwitz, Pauli Rämö, Klemens Rottner, Eugen Kerkhoff, Teiji Wada, Josef M Penninger, Niko Beerenwinkel, Peter Horvath, Christoph Dehio, Wolf-Dietrich Hardt
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161965 (2016)
Salmonella Typhimurium (S. Tm) is a leading cause of diarrhea. The disease is triggered by pathogen invasion into the gut epithelium. Invasion is attributed to the SPI-1 type 3 secretion system (T1). T1 injects effector proteins into epithelial cells
Externí odkaz:
https://doaj.org/article/5babca2e466f425b919d9eb22da76f5c
Autor:
Toshinori Agatsuma, Teiji Wada, Yusuke Ogitani, Saori Ishida, Chiaki Ishii, Tomomi Nakayama Iwata
Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate with a topoisomerase I inhibitor exatecan derivative (DX-8951 derivative, DXd), has been reported to exert potent antitumor effects in xenograft mouse models and clinical t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cc4bfc82e1325057b53049f71fa4423
https://doi.org/10.1158/1535-7163.c.6537951.v1
https://doi.org/10.1158/1535-7163.c.6537951.v1
Autor:
Toshinori Agatsuma, Teiji Wada, Yusuke Ogitani, Saori Ishida, Chiaki Ishii, Tomomi Nakayama Iwata
Supplementary Figure S1. The chemical structure of DS-8201a. Supplementary Figure S2. Importance of targeted delivery by the ADC. Supplementary Figure S3. Reduced antitumor effect of DS-8201a in an immunocompromised mouse model. Supplementary Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdc4816ae834f9b0be89e3a7b902f11
https://doi.org/10.1158/1535-7163.22505103
https://doi.org/10.1158/1535-7163.22505103
Autor:
Mayumi Sue, Takuya Tsubaki, Yoko Ishimoto, Shinko Hayashi, Saori Ishida, Yoshitaka Isumi, Jun Ishiguro, Reimi Kawaida, Toshiaki Ohtsuka, Teiji Wada, Toshinori Agatsuma, Norihito Kawasaki
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e37a9939ce76bc03610db0aae6e667e
https://doi.org/10.1136/jitc-2022-sitc2022.0808
https://doi.org/10.1136/jitc-2022-sitc2022.0808
Autor:
Shoichi Maruyama, Shinko Hayashi, Teiji Wada, Daisuke Sugiyama, Michinori Kadokura, Atsushi Tanemura, Kazuki Hirahara, Masato Amano, Ichiro Watanabe, Shiho Kozuma, Megumi Miyamoto, Kenichi Wakita, Atsushi Okamoto, Masato Hata, Kazuki Satoh, Takahiko Sato, Saori Ishida, Hiroyoshi Nishikawa, Helmut Jonuleit, Toshinori Agatsuma, Yoichi Kobayashi, Andrea Tuettenberg, Kyungtaek Lim, Kaori Fujimaki
Publikováno v:
International Immunology. 33:435-446
Regulatory T (Treg) cells, which are essential for maintaining self-tolerance, inhibit anti-tumor immunity, consequently hindering protective cancer immunosurveillance, and hampering effective anti-tumor immune responses in tumor-bearing hosts. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b04ab7e4554f7ec7fdf5b2a76565a27
https://doi.org/10.1093/intimm/dxab027
https://doi.org/10.1093/intimm/dxab027
Autor:
Daniel Schramek, Athanassios Kotsinas, Arabella Meixner, Teiji Wada, Ulrich Elling, J. Andrew Pospisilik, G. Gregory Neely, Ralf-Harun Zwick, Verena Sigl, Guido Forni, Manuel Serrano, Vassilis G. Gorgoulis, Josef M. Penninger
Publikováno v:
Nature Genetics. 55:891-891
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49c353ebb50857cf744acdbd05552eee
https://doi.org/10.1038/s41588-023-01387-x
https://doi.org/10.1038/s41588-023-01387-x
Autor:
Teiji Wada, Masataka Chihara, Shota Fukuoka, Hiroyoshi Nishikawa, Toshihiko Doi, Taku Yoshida, Koichiro Inaki, Katsuya Tsuchihara, Tatsuya Kawase, Akihiro Ohashi, Takahiro Kamada, Kohei Shitara, Yukie Kashima, Yukihiko Ebisuno, Yoshiaki Nakamura, Takuma Irie, Naofumi Taoka, Ayako Suzuki, Sakiyo Tsukamoto, Ryo Fujii, Yutaka Suzuki, Tatsunori Minamide, Yosuke Togashi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Single-cell level analysis is powerful tool to assess the heterogeneity of cellular components in tumor microenvironments (TME). In this study, we investigated immune-profiles using the single-cell analyses of endoscopically- or surgically-resected t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2523c4c31b32899eb46a72a94348b92e
https://doi.org/10.1038/s41598-020-79385-w
https://doi.org/10.1038/s41598-020-79385-w