Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Tegy J. Vadakkan"'
Autor:
Jonathan M. Kurie, Mitsuo Yamauchi, Samir M. Hanash, K. Jane Grande-Allen, Jennifer L. West, Mary E. Dickinson, John M. Hicks, Don L. Gibbons, Chad J. Creighton, Ignacio I. Wistuba, Jaime Rodriguez, Edwin Roger Parra Cuentas, Xin Liu, Jonathon D. Roybal, Young-Ho Ahn, Min P. Kim, Tegy J. Vadakkan, Bartley J. Gill, Li Sun, Monica Fahrenholtz, Brandi N. Baird, Mark J. Schliekelman, Masahiko Terajima, Yulong Chen, Daniela Pankova
A Matrigel surface was seeded first with GFP-tagged aggregates followed 24 h later by a CAF single-cell suspension. Time-lapse microscopy was immediately after CAF seeding. Scale bar, 200 μm. Movie compiled at 8 frames per second.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6adc06feb8a0e90434ce55a27f9c815
https://doi.org/10.1158/1541-7786.22512120
https://doi.org/10.1158/1541-7786.22512120
Autor:
Jonathan M. Kurie, Mitsuo Yamauchi, Samir M. Hanash, K. Jane Grande-Allen, Jennifer L. West, Mary E. Dickinson, John M. Hicks, Don L. Gibbons, Chad J. Creighton, Ignacio I. Wistuba, Jaime Rodriguez, Edwin Roger Parra Cuentas, Xin Liu, Jonathon D. Roybal, Young-Ho Ahn, Min P. Kim, Tegy J. Vadakkan, Bartley J. Gill, Li Sun, Monica Fahrenholtz, Brandi N. Baird, Mark J. Schliekelman, Masahiko Terajima, Yulong Chen, Daniela Pankova
A Matrigel surface was seeded first with GFP-tagged aggregates followed 24 h later by a CAF single-cell suspension. Time-lapse microscopy was initiated 24 hours after CAF seeding. Dissociating tumor aggregates migrate toward each other (arrow). Scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f683823f0756c14a4609cd2607c0368
https://doi.org/10.1158/1541-7786.22512117
https://doi.org/10.1158/1541-7786.22512117
Autor:
Jonathan M. Kurie, Mitsuo Yamauchi, Samir M. Hanash, K. Jane Grande-Allen, Jennifer L. West, Mary E. Dickinson, John M. Hicks, Don L. Gibbons, Chad J. Creighton, Ignacio I. Wistuba, Jaime Rodriguez, Edwin Roger Parra Cuentas, Xin Liu, Jonathon D. Roybal, Young-Ho Ahn, Min P. Kim, Tegy J. Vadakkan, Bartley J. Gill, Li Sun, Monica Fahrenholtz, Brandi N. Baird, Mark J. Schliekelman, Masahiko Terajima, Yulong Chen, Daniela Pankova
Intratumoral collagen cross-links heighten stromal stiffness and stimulate tumor cell invasion, but it is unclear how collagen cross-linking is regulated in epithelial tumors. To address this question, we used KrasLA1 mice, which develop lung adenoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbe9b0c7bbf014e842f399f6eca511c
https://doi.org/10.1158/1541-7786.c.6540138.v1
https://doi.org/10.1158/1541-7786.c.6540138.v1
Autor:
Chih-Wei Hsu, Ross A Poché, Jennifer E Saik, Saniya Ali, Shang Wang, Nejla Yosef, Gisele A Calderon, Larry Scott, Tegy J Vadakkan, Irina V Larina, Jennifer L West, Mary E Dickinson
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131643 (2015)
Successful engineering of complex organs requires improved methods to promote rapid and stable vascularization of artificial tissue scaffolds. Toward this goal, tissue engineering strategies utilize the release of pro-angiogenic growth factors, alone
Externí odkaz:
https://doaj.org/article/b810f1094e454f12a9af261f3c2cb050
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53546 (2013)
The microenvironment of the subependymal zone (SEZ) neural stem cell niche is necessary for regulating adult neurogenesis. In particular, signaling from the microvasculature is essential for adult neural stem cell maintenance, but microvascular struc
Externí odkaz:
https://doaj.org/article/63de774e0ae9467780e4ee6a9734f559
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1750 (2008)
Merkel cell-neurite complexes are highly sensitive touch receptors comprising epidermal Merkel cells and sensory afferents. Based on morphological and molecular studies, Merkel cells are proposed to be mechanosensory cells that signal afferents via n
Externí odkaz:
https://doaj.org/article/583e6f1267b045f39be4311a698f0fdd
Autor:
Rende Gu, Tegy J. Vadakkan, Andrew K. Groves, Tiantian Cai, Mary E. Dickinson, Alyssa L. Crowder, Victor G. Piazza, Rogers M. Brown, Chih-Wei Hsu
Publikováno v:
Developmental Biology. 414:72-84
The transcription factor Sox2 is both necessary and sufficient for the generation of sensory regions of the inner ear. It regulates expression of the Notch ligand Jag1 in prosensory progenitors, which signal to neighboring cells to up-regulate Sox2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b6fcd461c4b71b9c42bf5a3df50280
https://doi.org/10.1016/j.ydbio.2016.03.027
https://doi.org/10.1016/j.ydbio.2016.03.027
Autor:
Bartley J. Gill, Jonathon D. Roybal, Samir M. Hanash, Brandi N. Baird, Yulong Chen, Li Sun, Young Ho Ahn, Ignacio I. Wistuba, Edwin Roger Parra Cuentas, Xin Liu, Chad J. Creighton, Mary E. Dickinson, Jennifer L. West, K. Jane Grande-Allen, Min P. Kim, Masahiko Terajima, John Hicks, Jaime Rodriguez, Mark J. Schliekelman, Tegy J. Vadakkan, Jonathan M. Kurie, Monica M. Fahrenholtz, Mitsuo Yamauchi, Daniela Pankova, Don L. Gibbons
Publikováno v:
Molecular Cancer Research. 14:287-295
Intratumoral collagen cross-links heighten stromal stiffness and stimulate tumor cell invasion, but it is unclear how collagen cross-linking is regulated in epithelial tumors. To address this question, we used KrasLA1 mice, which develop lung adenoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ee3c809eccf2b37084dd7bf931184f
https://doi.org/10.1158/1541-7786.mcr-15-0307
https://doi.org/10.1158/1541-7786.mcr-15-0307
Autor:
Jean-Leon Thomas, Tegy J. Vadakkan, Ross A. Poché, Mary E. Dickinson, Nejla Yosef, June-Hee Park
Macrophages are well characterized as immune cells. However, in recent years, a multitude of non-immune functions have emerged many of which play essential roles in a variety of developmental processes (Wynn, Chawla and J. W. Pollard, 2013; DeFalco e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f3fc83321fe2b9b90f513c709f4c69
https://europepmc.org/articles/PMC6190604/
https://europepmc.org/articles/PMC6190604/
Autor:
Stephen T. C. Wong, Wen Bu, John D. Landua, Jeffrey M. Rosen, Tegy J. Vadakkan, Michael T. Lewis, Mei Zhang, Mary E. Dickinson, Wei Wei, Fuhai Li
Publikováno v:
Stem Cells Translational Medicine. 3:857-866
Cancer stem cells (CSCs, or tumor-initiating cells) may be responsible for tumor formation in many types of cancer, including breast cancer. Using high-resolution imaging techniques, we analyzed the relationship between a Wnt-responsive, CSC-enriched
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7346c019f4b207ad4f530620b9c4f6aa
https://doi.org/10.5966/sctm.2013-0088
https://doi.org/10.5966/sctm.2013-0088