Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Teffs"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Reactive oxygen species (ROS) are produced both enzymatically and non-enzymatically in vivo. Physiological concentrations of ROS act as signaling molecules that participate in various physiological and pathophysiological activities and play an import
Externí odkaz:
https://doaj.org/article/c4234dff31f74799aec82a91678d8fdb
Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders
Autor:
Jatin Machhi, Bhavesh D. Kevadiya, Ijaz Khan Muhammad, Jonathan Herskovitz, Katherine E. Olson, R. Lee Mosley, Howard E. Gendelman
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-26 (2020)
Abstract Emerging evidence demonstrates that adaptive immunity influences the pathobiology of neurodegenerative disorders. Misfolded aggregated self-proteins can break immune tolerance leading to the induction of autoreactive effector T cells (Teffs)
Externí odkaz:
https://doaj.org/article/6642148324e04928a77740aef34287ab
Autor:
Aaron D. Schwab, Mackenzie J. Thurston, Jatin Machhi, Katherine E. Olson, Krista L. Namminga, Howard E. Gendelman, R. Lee Mosley
Publikováno v:
Neurobiology of Disease, Vol 137, Iss , Pp 104760- (2020)
With the increasing prevalence of Parkinson’s disease (PD), there is an immediate need to interdict disease signs and symptoms. In recent years this need was met through therapeutic approaches focused on regenerative stem cell replacement and alpha
Externí odkaz:
https://doaj.org/article/1a60a14d3adc4ab8b54e43fc1314dc84
Autor:
Mackenzie J. Thurston, Krista L. Namminga, Aaron D. Schwab, R. Lee Mosley, Howard E. Gendelman, Katherine E. Olson, Jatin Machhi
Publikováno v:
Neurobiology of Disease, Vol 137, Iss, Pp 104760-(2020)
Neurobiology of disease
Neurobiology of disease
With the increasing prevalence of Parkinson’s disease (PD), there is an immediate need to interdict disease signs and symptoms. In recent years this need was met through therapeutic approaches focused on regenerative stem cell replacement and alpha
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 61-78 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 61-78 (2020)
Solute carrier (SLC) transporters meditate many essential physiological functions, including nutrient uptake, ion influx/efflux, and waste disposal. In its protective role against tumors and infections, the mammalian immune system coordinates complex
Autor:
Régnier, Paul
Publikováno v:
Immunologie. Université Sorbonne Paris Cité, 2018. Français. ⟨NNT : 2018USPCB133⟩
The cancer, one of the main causes of death in the world, can appear in almost any type of tissue, and is characterized by an anarchic proliferation of cells and the establishment of a tolerogenic immune response favouring the tumour growth, leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b275e8a37194b5b5eb7b1d3518ea3c04
https://tel.archives-ouvertes.fr/tel-03411100
https://tel.archives-ouvertes.fr/tel-03411100
Autor:
Régnier, Paul
Publikováno v:
Immunologie. Université Sorbonne Paris Cité, 2018. Français. ⟨NNT : 2018USPCB133⟩
The cancer, one of the main causes of death in the world, can appear in almost any type of tissue, and is characterized by an anarchic proliferation of cells and the establishment of a tolerogenic immune response favouring the tumour growth, leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::b275e8a37194b5b5eb7b1d3518ea3c04
https://theses.hal.science/tel-03411100/file/va_Regnier_Paul.pdf
https://theses.hal.science/tel-03411100/file/va_Regnier_Paul.pdf
Akademický článek
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Autor:
Götlind, Yu-Yuan Chiu
The two major forms of inflammatory bowel disease (IBD), Crohn's disease (CD) and ulcerative colitis (UC) are gastrointestinal disorders characterized by chronic and relapsing inflammation. Mice deficient in the inhibitory G protein subunit Gαi2 spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1149::ce6be604b2d719fd809c27d61f1b8b27
Akademický článek
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