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pro vyhledávání: '"Teena M Varghese"'
Autor:
Teena M Varghese, Michael F.A. Finley, Samantha J Allen, Paul L. Dudas, Jonathan E Schneeweis
Publikováno v:
SLAS discovery : advancing life sciences RD. 26(1)
Interleukin-23 (IL-23) is a key cytokine implicated in the pathogenesis of autoimmune disorders, including psoriasis and ulcerative colitis. Although targeted IL-23 antibody therapeutics are used clinically, there are no small-molecule therapeutics t
Autor:
Arjun Saha, Annie X. Liu, Samantha J Allen, Teena M Varghese, Michael D. Hack, Taraneh Mirzadegan
Publikováno v:
Journal of chemical information and modeling. 58(10)
Since many projects at pharmaceutical organizations get their start from a high-throughput screening (HTS) campaign, improving the quality of the HTS deck can improve the likelihood of discovering a high-quality lead molecule that can be progressed t