Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Teemu J Murtola"'
Autor:
Reetta Nätkin, Pasi Pennanen, Heimo Syvälä, Merja Bläuer, Juha Kesseli, Teuvo L J Tammela, Matti Nykter, Teemu J Murtola
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281645 (2023)
Androgen deprivation therapy is the cornerstone treatment of advanced prostate cancer. Eventually prostate cancer cells overcome androgen deprivation therapy, giving rise to castration resistant prostate cancer (CRPC) characterized by increased andro
Externí odkaz:
https://doaj.org/article/9203e67f881845b9a88f84cbfa676d4a
Autor:
Terho Lehtimäki, Antti Rannikko, Mikkel Fode, Michael Borre, Teuvo Tammela, Aino Siltari, Peter Østergren, Mika Helminen, Timo Marttila, Otto Ettala, Heikki Seikkula, Peter Boström, Jarno Riikonen, Juha Koskimäki, Tomi Pakarainen, Andres Kotsar, Paavo V Raittinen, Arto Salonen, Hanna Ronkainen, Sven Löffeler, Teemu J Murtola
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Introduction Blood cholesterol is likely a risk factor for prostate cancer prognosis and use of statins is associated with lowered risk of prostate cancer recurrence and progression. Furthermore, use of statins has been associated with prolonged time
Externí odkaz:
https://doaj.org/article/e505fd6f8e7d4cd2a0760857e0947b59
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234269 (2020)
The aim of this study was to investigate pre- and post-diagnostic use of antihypertensive drugs on prostate cancer (PCa)-specific survival and the initiation of androgen deprivation therapy (ADT). The cohort investigated 8,253 PCa patients with 837 P
Externí odkaz:
https://doaj.org/article/55d41b56ab1e495d91a225b5ad9d3f0d
Autor:
Teemu J. Murtola, Aino Siltari, Paavo Raittinen, Teuvo L.J. Tammela, Stig Linder, Anita Csizmarik, Gero Kramer, Tibor Szarvas
Publikováno v:
European Urology Open Science, Vol 70, Iss , Pp 135-141 (2024)
Background and objective: Prostate-specific antigen (PSA) is of limited value as a surrogate marker for overall survival (OS) in prostate cancer (PC). Serum thymidine kinase 1 (sTK1) is an enzyme expressed by actively dividing cells. Our aim was to e
Externí odkaz:
https://doaj.org/article/f5f7b70d5e4c48bf8a57e54d730f0797
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153413 (2016)
Non-steroidal anti-inflammatory drugs (NSAIDs), especially aspirin, have been associated with lowered cancer incidence and mortality. We examined overall cancer mortality and mortality from specific cancer sites among the 80,144 men in the Finnish Pr
Externí odkaz:
https://doaj.org/article/bbc234c3d8e34eb0a2c6656c81796b71
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110231 (2014)
Recent studies have suggested that statins, an established drug group in the prevention of cardiovascular mortality, could delay or prevent breast cancer recurrence but the effect on disease-specific mortality remains unclear. We evaluated risk of br
Externí odkaz:
https://doaj.org/article/8d18e3be7b97452b995199c644cf34ad
Autor:
Teemu J Murtola, Heimo Syvälä, Pasi Pennanen, Merja Bläuer, Tiina Solakivi, Timo Ylikomi, Teuvo L J Tammela
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39445 (2012)
Cholesterol-lowering treatment has been suggested to delay progression of prostate cancer by decreasing serum LDL. We studied in vitro the effect of extracellular LDL-cholesterol on the number of prostate epithelial cells and on the expression of key
Externí odkaz:
https://doaj.org/article/a8729a04aba042b29caa24e45271cc4e
Autor:
Mina Sattari, Annika Kohvakka, Elaheh Moradi, Hanna Rauhala, Henna Urhonen, William B Isaacs, Matti Nykter, Teemu J Murtola, Teuvo L. J. Tammela, Leena Latonen, G. Steven Bova, Juha Kesseli, Tapio Visakorpi
Publikováno v:
Endocrine-Related Cancer.
Prostate cancer (PCa) is the second-most common cause of male cancer-related death in western industrialized countries, and the emergence of metastases is a key challenge in the treatment of PCa. Accumulating studies have shown that long noncoding RN
Autor:
Teemu J Murtola, Kaisa M Skantsi, Kirsi Talala, Kimmo Taari, Teuvo LJ Tammela, Johanna Schleutker, Anssi Auvinen, Csilla Sipeky
Although platelets and thrombosis play a role in cancer progression, anticoagulant drug warfarin has not been independently associated with prostate cancer (PCa) survival. SNPs altering warfarin metabolism may in theory affect the association. We inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96ef24fd49bdbd29d16c7ef0e9983e9b
https://doi.org/10.21203/rs.3.rs-2353582/v1
https://doi.org/10.21203/rs.3.rs-2353582/v1
Autor:
Lotta H. Nygård, Kirsi Talala, Kimmo Taari, Teuvo L. J. Tammela, Anssi Auvinen, Teemu J. Murtola
Publikováno v:
The ProstateREFERENCES.
Diabetes has been associated with an increased risk of benign prostatic hyperplasia (BPH). However, the role of antidiabetic drugs as a BPH risk factor is unclear. The objective of our study was to examine the risk of BPH by antidiabetic drug use and