Výsledky vyhledávání - "Teddy Happillon"

Diagnosis approach of chronic lymphocytic leukemia on unstained blood smears using Raman microspectroscopy and supervised classification

Autor: Teddy Happillon, Valérie Untereiner, Michel Manfait, Jacques Klossa, Abdelilah Beljebbar, Cyril Gobinet, Alain Delmer, Sylvie Daliphard, Pascale Cornillet-Lefebvre, Xavier Troussard, Anne Quinquenel

Publikováno v: The Analyst. 140:4465-4472

We have investigated the potential of Raman microspectroscopy combined with supervised classification algorithms to diagnose a blood lymphoproliferative disease, namely chronic lymphocytic leukemia (CLL). This study was conducted directly on human bl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfae53d039f914bff97bd7c0eba316d
https://doi.org/10.1039/c4an02085e

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Raman comparison of skin dermis of different ages: focus on spectral markers of collagen hydration

Autor: The Thuong Nguyen, Teddy Happillon, Jezabel Feru, Sylvie Brassart-Passco, Jean-François Angiboust, Michel Manfait, Olivier Piot

Publikováno v: Journal of Raman Spectroscopy. 44:1230-1237

Skin aging is the most visible sign of aging of the body. This complex process involves molecular and structural alterations of the main skin constituents. The major cutaneous constituent is type I collagen that gives strength and resilience to the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a22eb938f4f965c3be5fd87b451e5968
https://doi.org/10.1002/jrs.4355

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La biophotonique au service de l’identification de marqueurs pronostiques intracellulaires

Autor: R. Dagiral, Abdelilah Beljebbar, Georges Flandrin, P. Rideau, Jacques Klossa, S. Daliphard, Véronique Saada, A. Vievard, Teddy Happillon, V. Coomans, X. Troussard, P. Vielh, Valérie Untereiner, Michel Manfait, E. Froigneux, Jesús Angulo, Cyril Gobinet, Santiago Velasco-Forero, S. Roux

Publikováno v: Innovation and Research in BioMedical engineering
Innovation and Research in BioMedical engineering, Elsevier Masson, 2011, 32 (2), pp.72-75. ⟨10.1016/j.irbm.2011.01.039⟩

International audience; Using biophotonics techniques to retrieve prognostic intracellular signatures : IHMO project aims at developing a multimodal microscopy platform that includes in a single machine Raman micro spectroscopy and multispectral imag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48e330439d38ea47b4cadae0448ae10
https://doi.org/10.1016/j.irbm.2011.01.039

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Investigating the relationship between changes in collagen fiber orientation during skin aging and collagen/water interactions by polarized-FTIR microimaging

Autor: Jean-François Angiboust, Michel Manfait, Marie-Danièle Diebold, Teddy Happillon, Christophe Eklouh-Molinier, Nicole Bouland, Sylvie Brassart-Pasco, Olivier Piot, Caroline Fichel

Publikováno v: Analyst
Analyst, Royal Society of Chemistry, 2015, 140, pp.6260-6268. ⟨10.1039/c5an00278h⟩

International audience; Upon chronological aging, human skin undergoes structural and molecular modifications, especially at the level of type I collagen. This macromolecule is one of the main dermal structural proteins and presents several age-relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f6515f0d156ee4bb5dfbaa59dbadec
https://hal.inrae.fr/hal-03170580

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Probing non-enzymatic glycation of type I collagen: A novel approach using Raman and infrared biophotonic methods

Autor: Teddy Happillon, Valérie Untereiner, Ganesh D. Sockalingum, Georges Said, Marie Guilbert, Pierre Jeannesson, Roselyne Garnotel

Publikováno v: BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2013, 1830 (6), pp.3525-3531

Background Non-enzymatic glycation is the main post-translational modification of long-life proteins observed during aging and physiopathological processes such as diabetes and atherosclerosis. Type I collagen, the major component in matrices and tis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9612f4d039a348d6ee44c7bd6301b289
https://hal.archives-ouvertes.fr/hal-00832941

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Raman microspectroscopy detects epigenetic modifications in living Jurkat leukemic cells

Autor: Teddy Happillon, Aurelie Trussardi-Regnier, Philippe Bernard, Michel Manfait, Olivier Piot, Frank Antonicelli, Mathilde Poplineau, Jean Dufer

Publikováno v: Epigenomics
Epigenomics, Future Medicine, 2011, 6 (6), pp.785-794
Epigenomics, Future Medicine, 2011, 3, pp.785-794

Aims: Classical biochemical and molecular methods for discerning cells with epigenetic modifications are often biologically perturbing or even destructive. We wondered whether the noninvasive laser tweezer Raman spectroscopy technique allowed the dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96830bdb9ee2c7391fb755108185daae
https://pubmed.ncbi.nlm.nih.gov/22126296

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Détection automatique de bouffées d'activité contractile sur l'EHG par utilisation du critère d'information bayésien

Autor: Teddy Happillon, Charles Muszynski, Dan Istrate, Catherine Marque

Publikováno v: HAL
Journées d'Etude sur la TéléSANté, 6ème edition
Journées d'Etude sur la TéléSANté, 6ème edition, Pôle Capteurs, Université d'Orléans, May 2017, Bourges, France

International audience; La détection automatique de contractions à partir de l’électrohystérogramme (EHG), est de grand intérêt dans l’optique d’une surveillance de grossesse à domicile. Dans cette étude préliminaire, nous tentons de r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2deb42fc89ddfbeb81f735d2405c15c1
https://hal.archives-ouvertes.fr/hal-01565012

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Quantitative phase imaging and Raman micro-spectroscopy applied to Malaria

Autor: Pierre Bon, Benoit Wattelier, Teddy Happillon, Lucie de Laulanie, Valérie Untereiner, D. Toubas, Jacques Klossa, Michel Manfait

Publikováno v: Diagnostic Pathology

Background Malaria is due to parasitism of red blood cells (RBC) by protozoan parasites of the genus Plasmodium. Three main parameters have to be determined for patient treatment: parasite species, the rate of infected blood cells (parasitemia), and

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Label free technologies: Raman micro-spectroscopy and multi-spectral imaging for lymphocyte classification

Autor: Teddy Happillon, Sylvie Daliphard, Xavier Troussard, Michel Manfait, Véronique Saada, Abdelilah Beljebbar, Georges Flandrin, Cyril Gobinet, Jacques Klossa, Valérie Untereiner, Santiago Velasco-Forero, Jesús Angulo, Pascale Cornillet-Lefebvre

Publikováno v: Diagnostic Pathology

Background Current diagnostic and prognostic approaches in oncology use morphological and molecular techniques which lead to patient personalized therapies. However, they are still complex and hard to standardize. This is also true for Chronic Lympho

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