Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ted Wong"'
Autor:
Helen M. Gunter, Scott E. Youlten, Andre L. M. Reis, Tim McCubbin, Bindu Swapna Madala, Ted Wong, Igor Stevanovski, Arcadi Cipponi, Ira W. Deveson, Nadia S. Santini, Sarah Kummerfeld, Peter I. Croucher, Esteban Marcellin, Tim R. Mercer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The expression of genes encompasses their transcription into mRNA followed by translation into protein. In recent years, next-generation sequencing and mass spectrometry methods have profiled DNA, RNA and protein abundance in cells. However,
Externí odkaz:
https://doaj.org/article/9596d107d6324684931ffa09eb32bdd9
Autor:
Helen M. Gunter, Senel Idrisoglu, Swati Singh, Dae Jong Han, Emily Ariens, Jonathan R. Peters, Ted Wong, Seth W. Cheetham, Jun Xu, Subash Kumar Rai, Robert Feldman, Andy Herbert, Esteban Marcellin, Romain Tropee, Trent Munro, Tim R. Mercer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The success of mRNA vaccines has been realised, in part, by advances in manufacturing that enabled billions of doses to be produced at sufficient quality and safety. However, mRNA vaccines must be rigorously analysed to measure their integri
Externí odkaz:
https://doaj.org/article/8388e058a320472e9d9b36af0a5c254f
Autor:
Helen M. Gunter, Scott E. Youlten, Bindu Swapna Madala, Andre L. M. Reis, Igor Stevanovski, Ted Wong, Sarah K. Kummerfield, Ira W. Deveson, Nadia S. Santini, Esteban Marcellin, Tim R. Mercer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Adding library adaptors to DNA samples is an essential step in preparing samples for next-generation sequencing. Here, Gunter et al. describe the development of Control Library Adaptors (CAPTORs), that correct sequencing errors and normalise quantita
Externí odkaz:
https://doaj.org/article/c95ea1cb19834527b5286ab08b1dfd4d
Autor:
Andre L. M. Reis, Ira W. Deveson, Bindu Swapna Madala, Ted Wong, Chris Barker, Joshua Xu, Niall Lennon, Weida Tong, Tim R. Mercer, on behalf of the SEQC2 Consortium
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-24 (2022)
Abstract Background Next-generation sequencing (NGS) can identify mutations in the human genome that cause disease and has been widely adopted in clinical diagnosis. However, the human genome contains many polymorphic, low-complexity, and repetitive
Externí odkaz:
https://doaj.org/article/6671d1a5ecf947e5acd6de1c74fe8b9b
Autor:
Andre L. M. Reis, Ira W. Deveson, Ted Wong, Bindu Swapna Madala, Chris Barker, James Blackburn, Esteban Marcellin, Tim R. Mercer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Standard units of measurement are required for a quantitative description of the genome. Here, the authors present a universal synthetic DNA ladder that can measure genetic abundance in next-generation sequencing libraries.
Externí odkaz:
https://doaj.org/article/0b59cd1d8fef4ad1a20fa96cf583dfcb
Autor:
Ira W. Deveson, Bindu Swapna Madala, James Blackburn, Chris Barker, Ted Wong, Kirston M. Barton, Martin A. Smith, D. Neil Watkins, Tim R. Mercer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Any DNA sequence can be represented by a chiral partner sequence – an exact copy arranged in reverse nucleotide order. Here, the authors show that chiral DNA sequence pairs share important properties and show the utility of synthetic chiral sequenc
Externí odkaz:
https://doaj.org/article/eff97fe0e26c48849a3f468dba362eb7
Autor:
Simon A. Hardwick, Wendy Y. Chen, Ted Wong, Bindu S. Kanakamedala, Ira W. Deveson, Sarah E. Ongley, Nadia S. Santini, Esteban Marcellin, Martin A. Smith, Lars K. Nielsen, Catherine E. Lovelock, Brett A. Neilan, Tim R. Mercer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Complex microbial communities pose a challenge to metagenomic analysis. Here the authors develop ‘sequins’, internal DNA standards that represent a synthetic community of artificial genomes.
Externí odkaz:
https://doaj.org/article/db9f1c1f4bb54a1cb1792bb0e5f72ff5
Publikováno v:
International Journal of Food Studies, Vol 1, Iss 1 (2012)
A response study and the effects of different parameters (pH, temperature and enzyme dose) on kinetics of isolated soy protein hydrolysis by a trypsin-like endopeptidase (TL1) were conducted. Degree of hydrolysis (%DH) data varied at different times
Externí odkaz:
https://doaj.org/article/d6fe1821ba3044f29830ec6f95f861ef
Autor:
Milan Fernando, Scott Lee, Jesse R. Wark, Di Xiao, Benjamin Y. Lim, Michelle O’Hara-Wright, Hani J. Kim, Grady C. Smith, Ted Wong, Erdahl T. Teber, Robin R. Ali, Pengyi Yang, Mark E. Graham, Anai Gonzalez-Cordero
Publikováno v:
Stem Cell Reports. 17:1476-1492
Advances in the study of neurological conditions have been possible because of pluripotent stem cell technologies and organoids. Studies have described the generation of neural ectoderm-derived retinal and brain structures from pluripotent stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c89b49c6deb532647f40ad398e1fc06d
https://doi.org/10.1016/j.stemcr.2022.04.003
https://doi.org/10.1016/j.stemcr.2022.04.003
Autor:
Esteban Marcellin, Bindu Swapna Madala, Christopher M. Barker, James Blackburn, Andre L. M. Reis, Ira W. Deveson, Ted Wong, Tim R. Mercer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Standard units of measurement are required for the quantitative description of nature; however, few standard units have been established for genomics to date. Here, we have developed a synthetic DNA ladder that defines a quantitative standard unit th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5847b70f75a2043ce5131e417234fb78
http://link.springer.com/article/10.1038/s41467-020-17445-5
http://link.springer.com/article/10.1038/s41467-020-17445-5