Výsledky vyhledávání - "Ted T Ashburn"

Akademický článek

Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

The development of neutralizing antibodies can limit the therapeutic effectiveness of systemically administered oncolytic viruses (OV). Here, to enable repeated intravenous administration, the authors report the development of synthetic RNA viruses f

Externí odkaz: https://doaj.org/article/e35ea397d9ba41b5b30d0dfa85eb8713

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Structural model for the β-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide

Autor: Hendsch Zs, Peter T. Lansbury, Simon Ej, Richard G. Spencer, Kocisko Da, Ted T. Ashburn, Michèle Auger, Janet M. Griffiths, Kurt J. Halverson, Philip R. Costa

Publikováno v: Nature Structural & Molecular Biology. 2:990-998

Amyloids are a class of noncrystalline, yet ordered, protein aggregates. A new approach was used to provide the initial structural data on an amyloid fibril--comprising a peptide (beta 34-42) from the C-terminus of the beta-amyloid protein--based on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7ecafb446a343bae534de569ae05aa
https://doi.org/10.1038/nsb1195-990

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Drug repositioning: identifying and developing new uses for existing drugs

Autor: Ted T. Ashburn, Karl B. Thor

Publikováno v: Nature reviews. Drug discovery. 3(8)

Biopharmaceutical companies attempting to increase productivity through novel discovery technologies have fallen short of achieving the desired results. Repositioning existing drugs for new indications could deliver the productivity increases that th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820e4089a66bc6a714e01b252e7e944e
https://pubmed.ncbi.nlm.nih.gov/15286734

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Human tissue research in the genomic era of medicine: balancing individual and societal interests

Autor: Ted T. Ashburn, Barry I. Eisenstein, Sharon K. Wilson

Publikováno v: Archives of internal medicine. 160(22)

Advances in DNA sequencing technology and in our understanding of the human genome are ushering in a new era of genomic medicine, one with dramatic potential to not only benefit society through research involving human tissue, but also to cause econo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd9148699e978ac8708188aa3bb2f5d
https://pubmed.ncbi.nlm.nih.gov/11493153

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